Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Tassanee Lerksuthirat"'
Publikováno v:
Healthcare Informatics Research, Vol 29, Iss 3, Pp 269-279 (2023)
Objectives Twitter has been used to express a diverse range of public opinions about cannabis legalization in Thailand. The purpose of this study was to observe changes in sentiments after cannabis legalization and to investigate health-related topic
Externí odkaz:
https://doaj.org/article/cda9b0cf0545435395882ba988e03b73
PARP1pred: a web server for screening the bioactivity of inhibitors against DNA repair enzyme PARP-1
Autor:
Tassanee Lerksuthirat, Sermsiri Chitphuk, Wasana Stitchantrakul, Donniphat Dejsuphong, Aijaz Ahmad Malik, Chanin Nantasenamat
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 22, Pp 84-107 (2023)
Cancer is the leading cause of death worldwide, resulting in the mortality of more than 10 million people in 2020, according to Global Cancer Statistics 2020. A potential cancer therapy involves targeting the DNA repair process by inhibiting PARP-1.
Externí odkaz:
https://doaj.org/article/5a7513611529407db49b6202f3926303
Autor:
Tassanee Lerksuthirat, Pasinee On‐yam, Sermsiri Chitphuk, Wasana Stitchantrakul, David S. Newburg, Ardythe L. Morrow, Suradej Hongeng, Wararat Chiangjong, Somchai Chutipongtanate
Publikováno v:
Global Challenges, Vol 7, Iss 3, Pp n/a-n/a (2023)
Abstract Anticancer peptides (ACPs) are rising as a new strategy for cancer therapy. However, traditional laboratory screening to find and identify novel ACPs from hundreds to thousands of peptides is costly and time consuming. Here, a sequential pro
Externí odkaz:
https://doaj.org/article/18ae5a0382bb4d9a89f3fd160df78fda
Autor:
Thipwimol Tim-Aroon, Khunton Wichajarn, Kamornwan Katanyuwong, Pranoot Tanpaiboon, Nithiwat Vatanavicharn, Kullasate Sakpichaisakul, Arthaporn Kongkrapan, Jakris Eu-ahsunthornwattana, Supranee Thongpradit, Kanya Moolsuwan, Nusara Satproedprai, Surakameth Mahasirimongkol, Tassanee Lerksuthirat, Bhoom Suktitipat, Natini Jinawath, Duangrurdee Wattanasirichaigoon
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Sandhoff disease (SD) is an autosomal recessive lysosomal storage disorder, resulting in accumulation of GM2 ganglioside, particular in neuronal cells. The disorder is caused by deficiency of β-hexosaminidase B (HEX-B), due to pa
Externí odkaz:
https://doaj.org/article/5793a6bb9459425ea999df2f70d8699e
Autor:
Rakkreat Wikiniyadhanee, Tassanee Lerksuthirat, Wasana Stitchantrakul, Sermsiri Chitphuk, Thanyachai Sura, Donniphat Dejsuphong
Publikováno v:
FEBS Open Bio, Vol 10, Iss 10, Pp 2055-2071 (2020)
Tripartite motif‐containing protein 29 (TRIM29) is involved in DNA double‐strand break (DSB) repair. However, the specific roles of TRIM29 in DNA repair are not clearly understood. To investigate the involvement of TRIM29 in DNA DSB repair, we di
Externí odkaz:
https://doaj.org/article/780932cbbbd44c02bf790b37d879fc90
Autor:
Wararat Chiangjong, Jirawan Panachan, Thitinee Vanichapol, Nutkridta Pongsakul, Pongpak Pongphitcha, Teerapong Siriboonpiputtana, Tassanee Lerksuthirat, Pracha Nuntnarumit, Sarayut Supapannachart, Chantragan Srisomsap, Jisnuson Svasti, Suradej Hongeng, Somchai Chutipongtanate
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 981 (2021)
Chemotherapy in childhood leukemia is associated with late morbidity in leukemic survivors, while certain patient subsets are relatively resistant to standard chemotherapy. It is therefore important to identify new agents with sensitivity and selecti
Externí odkaz:
https://doaj.org/article/a7c657feb9f448a78970e966cad35a2a
Autor:
Tassanee Lerksuthirat, Rakkreat Wikiniyadhanee, Sermsiri Chitphuk, Wasana Stitchantrakul, Somponnat Sampattavanich, Siwanon Jirawatnotai, Juangjun Jumpathong, Donniphat Dejsuphong
Publikováno v:
Biomolecules, Vol 10, Iss 12, p 1680 (2020)
Recent developments in chemotherapy focus on target-specific mechanisms, which occur only in cancer cells and minimize the effects on normal cells. DNA damage and repair pathways are a promising target in the treatment of cancer. In order to identify
Externí odkaz:
https://doaj.org/article/3930ab349b5c4d70b5950e5856eaf543
Autor:
Huafeng Wang, Mengyi Li, Chiung Yu Hung, Meenal Sinha, Linda M Lee, Darin L Wiesner, Vanessa LeBert, Tassanee Lerksuthirat, Kevin Galles, Marulasiddappa Suresh, Anthony L DeFranco, Clifford A Lowell, Bruce S Klein, Marcel Wüthrich
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005787 (2016)
Soaring rates of systemic fungal infections worldwide underscore the need for vaccine prevention. An understanding of the elements that promote vaccine immunity is essential. We previously reported that Th17 cells are required for vaccine immunity to
Externí odkaz:
https://doaj.org/article/39786d3e904b4e06849cf346410a9e6d
Autor:
Tassanee Lerksuthirat, Tassanee Lohnoo, Ruchuros Inkomlue, Thidarat Rujirawat, Wanta Yingyong, Rommanee Khositnithikul, Narumon Phaonakrop, Sittiruk Roytrakul, Thomas D Sullivan, Theerapong Krajaejun
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0118547 (2015)
Pythium insidiosum is a unique oomycete that can infect humans and animals. Patients with a P. insidiosum infection (pythiosis) have high rates of morbidity and mortality. The pathogen resists conventional antifungal drugs. Information on the biology
Externí odkaz:
https://doaj.org/article/ff0ef0cb4a54443480649a63ef7de624
Autor:
Rakkreat Wikiniyadhanee, Tassanee Lerksuthirat, Wasana Stitchantrakul, Sermsiri Chitphuk, Shunichi Takeda, Donniphat Dejsuphong
Publikováno v:
BioMed Research International. 2023:1-12
The inhibition of poly(ADP-ribose) polymerases (PARPs) and ataxia telangiectasia and Rad3-related (ATR) would be an alternative approach for cancer treatments. The aim of this study is to investigate the synergy of the different combinations of PARP