Hearing loss and vestibular schwannoma: new insights into Schwann cells implication

Autor: Tasnim Mohamed, Valentina Melfi, Alessandra Colciago, Valerio Magnaghi

Publikováno v: Cell Death and Disease, Vol 14, Iss 9, Pp 1-12 (2023)

Abstract Hearing loss (HL) is the most common and heterogeneous disorder of the sensory system, with a large morbidity in the worldwide population. Among cells of the acoustic nerve (VIII cranial nerve), in the cochlea are present the hair cells, the

Externí odkaz: https://doaj.org/article/8de2cd6bd2eb4e01b2b81fa2a24a0f5e

Protein kinase C epsilon activation regulates proliferation, migration, and epithelial to mesenchymal-like transition in rat Schwann cells

Autor: Tasnim Mohamed, Alessandra Colciago, Marina Montagnani Marelli, Roberta Manuela Moretti, Valerio Magnaghi

Publikováno v: Frontiers in Cellular Neuroscience, Vol 17 (2023)

IntroductionProtein kinase type C-ε (PKCε) plays an important role in the sensitization of primary afferent nociceptors, promoting mechanical hyperalgesia. In accordance, we showed that PKCε is present in sensory neurons of the peripheral nervous

Externí odkaz: https://doaj.org/article/a5d3f3d0386f4631b6db5fa17a966b4c

Transcriptomic Profile Reveals Deregulation of Hearing-Loss Related Genes in Vestibular Schwannoma Cells Following Electromagnetic Field Exposure

Autor: Valentina Melfi, Peter A. Greer, Adam J Reid, Valerio Magnaghi, Nico Mitro, Alessandra Colciago, Veronica Bonalume, Tasnim Mohamed, Alessandro Faroni, Matteo Audano

Publikováno v: Cells, Vol 10, Iss 1840, p 1840 (2021)
Cells
Volume 10
Issue 7
Colciago, A, Audano, M, Bonalume, V, Melfi, V, Mohamed, T, Reid, A J, Faroni, A, Greer, P A, Mitro, N & Magnaghi, V 2021, ' Transcriptomic Profile Reveals Deregulation of Hearing-Loss Related Genes in Vestibular Schwannoma Cells Following Electromagnetic Field Exposure ', Cells, vol. 10, no. 7, 1840 . https://doi.org/10.3390/cells10071840

Hearing loss (HL) is the most common sensory disorder in the world population. One common cause of HL is the presence of vestibular schwannoma (VS), a benign tumor of the VIII cranial nerve, arising from Schwann cell (SC) transformation. In the last

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a0cb440c36120d1a9d95398e2d30d7
https://doi.org/10.3390/cells10071840