Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tasnim Chakroun"'
Autor:
Elisabeth Findeiss, Sigrid C. Schwarz, Valentin Evsyukov, Thomas W. Rösler, Matthias Höllerhage, Tasnim Chakroun, Niko-Petteri Nykänen, Yimin Shen, Wolfgang Wurst, Michael Kohl, Jörg Tost, Günter U. Höglinger
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Growing evidence suggests that epigenetic mechanisms like microRNA-mediated transcriptional regulation contribute to the pathogenesis of parkinsonism. In order to study the influence of microRNAs (miRNAs), we analyzed the miRNome 2 days prior to majo
Externí odkaz:
https://doaj.org/article/5ea6ed3d0f4e48c1a2e0aa7a04f73b6a
Autor:
Matthias Höllerhage, Andreas Wolff, Tasnim Chakroun, Valentin Evsyukov, Linghan Duan, Oscar Wing-Ho Chua, Qilin Tang, Thomas Koeglsperger, Günter U. Höglinger
Publikováno v:
Molecular neurobiology 59, 3980-3995 (2022). doi:10.1007/s12035-022-02824-4
Spreading of alpha-synuclein (αSyn) may play an important role in Parkinson’s disease and related synucleinopathies. Passive immunization with anti-αSyn antibodies is a promising method to slow down the spreading process and thereby the progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::646a445dee8848bf00a0936d25d54201
https://doi.org/10.1007/s12035-022-02824-4
https://doi.org/10.1007/s12035-022-02824-4
Autor:
Elisabeth Findeiss, Sigrid C. Schwarz, Valentin Evsyukov, Thomas W. Rösler, Matthias Höllerhage, Tasnim Chakroun, Niko-Petteri Nykänen, Yimin Shen, Wolfgang Wurst, Michael Kohl, Jörg Tost, Günter U. Höglinger
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in cell and developmental biology 9, 561086 (2021). doi:10.3389/fcell.2021.561086
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in cell and developmental biology 9, 561086 (2021). doi:10.3389/fcell.2021.561086
Growing evidence suggests that epigenetic mechanisms like microRNA-mediated transcriptional regulation contribute to the pathogenesis of parkinsonism. In order to study the influence of microRNAs (miRNAs), we analyzed the miRNome 2 days prior to majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083a1fb7a8ecf36e999702f4ddcb3677
https://pubmed.ncbi.nlm.nih.gov/33748099
https://pubmed.ncbi.nlm.nih.gov/33748099
Autor:
Wolfgang Wurst, Frits Kamp, Günter U. Höglinger, Valentin Evsyukov, Viktoria Ruf, Tasnim Chakroun, Matthias Höllerhage, Thomas W. Rösler, Andreas Schmidt, Niko-Petteri Nykänen
Publikováno v:
Cell Death & Disease
Cell Death Dis. 11:84 (2020)
Cell death & disease 11(2), 84 (2020). doi:10.1038/s41419-020-2285-7
Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Cell Death Dis. 11:84 (2020)
Cell death & disease 11(2), 84 (2020). doi:10.1038/s41419-020-2285-7
Cell Death and Disease, Vol 11, Iss 2, Pp 1-16 (2020)
Aggregation of alpha-synuclein (αSyn) is a crucial event underlying the pathophysiology of synucleinopathies. The existence of various intracellular and extracellular αSyn species, including cleaved αSyn, complicates the quest for an appropriate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8e5ab334ca0ac21d68406a128f81050
http://europepmc.org/articles/PMC6997403
http://europepmc.org/articles/PMC6997403
Autor:
Carmelo Sgobio, Thomas Koeglsperger, Pan Gao, Felix Machleid, Thomas Arzberger, Kai Bötzel, Tasnim Chakroun, Jochen Herms, Mathias Höllerhage, Yi Tan, Jörg Tost, Elisabeth Findeis, Günter U. Höglinger, Qilin Tang
Publikováno v:
Acta neuropathologica 139(2), 319-345 (2020). doi:10.1007/s00401-019-02099-5
Parkinson's disease (PD) is the most common neurodegenerative movement disorder and is characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the gradual appearance of α-synuclein (α-syn)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e996d6de49f55b30ce9d8646c655e3f
Autor:
Matthias Höllerhage, P. Gao, Q. Tang, Günter U. Höglinger, Thomas Koeglsperger, Carmelo Sgobio, Thomas Arzberger, Kai Bötzel, Tasnim Chakroun, Jörg Tost, Jochen Herms, F. Machleid, E. Findeis, Y. Tan
Publikováno v:
Parkinsonism & Related Disorders. 79:e73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::404ad8c4f6eee69b25f97849e6e29206
https://doi.org/10.1016/j.parkreldis.2020.06.269
https://doi.org/10.1016/j.parkreldis.2020.06.269
Autor:
Niko-Petteri Nykänen, Christian Behrends, Tasnim Chakroun, Thomas W. Rösler, Günter U. Höglinger, Matthias Höllerhage, Wolfgang Wurst, Natascha Fussi, Thomas Koeglsperger
Publikováno v:
Cell Death & Disease
Cell death & disease 9(7), 757 (2018). doi:10.1038/s41419-018-0816-2
Cell Death Dis. 9:757 (2018)
Cell Death and Disease, Vol 9, Iss 7, Pp 1-14 (2018)
Cell death & disease 9(7), 757 (2018). doi:10.1038/s41419-018-0816-2
Cell Death Dis. 9:757 (2018)
Cell Death and Disease, Vol 9, Iss 7, Pp 1-14 (2018)
Accumulation of pathological α-synuclein aggregates plays a major role in Parkinson’s disease. Macroautophagy is a mechanism to degrade intracellular protein aggregates by wrapping them into autophagosomes, followed by fusion with lysosomes. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e67db4b35d781952b4f15ab3f031b9
http://europepmc.org/articles/PMC6037700
http://europepmc.org/articles/PMC6037700