Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Tasneem Zahir"'
Autor:
Xiaodong Guo, Tasneem Zahir, Andrea Mothe, Molly S. Shoichet, Cindi M. Morshead, Yusuke Katayama, Charles H. Tator Ph.D., M.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Adult central mammalian axons show minimal regeneration after spinal cord injury due to loss of oligodendrocytes, demyelination of surviving axons, absence of growth-promoting molecules, and inhibitors of axonal outgrowth. In the present study, we at
Externí odkaz:
https://doaj.org/article/10cd97e537bd4e3ea57fa38a787cd71d
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21744 (2011)
Neural stem/progenitor cells (NSPCs) have great potential as a cell replacement therapy for spinal cord injury. However, poor control over transplant cell differentiation and survival remain major obstacles. In this study, we asked whether dibutyryl
Externí odkaz:
https://doaj.org/article/72b97b40c42c40399d2a02bd82bd7fc4
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27079 (2011)
Neural stem/progenitor cell (NSPC) transplantation is a promising therapy for spinal cord injury (SCI). However, little is known about NSPC from the adult human spinal cord as a donor source. We demonstrate for the first time that multipotent and sel
Externí odkaz:
https://doaj.org/article/8645b001fef64509b23f8f802ab564e6
Autor:
Tasneem Zahir, Hiroshi Nomura, Xiao Dong Guo, Howard Kim, Charles Tator, Cindi Morshead, Molly Shoichet
Publikováno v:
Cell Transplantation, Vol 17 (2008)
The aim of this study was to understand the survival and differentiation of neural stem/progenitor cells (NSPCs) cultured on chitosan matrices in vivo in a complete transection model of spinal cord injury. NSPCs were isolated from the subependyma of
Externí odkaz:
https://doaj.org/article/b0b77117910b4ac4ba8b6f4e177cb405
Autor:
Andrea J. Mothe, Molly S. Shoichet, Howard Kim, Gokhan Bozkurt, Tasneem Zahir, Charles H. Tator
Publikováno v:
Neurosurgery. 67:1733-1744
OBJECTIVE: We evaluated the survival and differentiation capacity of neural stem/ progenitor cells (NSPCs) derived from the adult rat spinal cord and seeded on intramedullary chitosan channels that were implanted in a subacute rat spinal cord injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44f87358ae491b792d0543beb692137
https://doi.org/10.1227/neu.0b013e3181f9af35
https://doi.org/10.1227/neu.0b013e3181f9af35
Publikováno v:
Biomaterials. 29:4676-4683
Neural stem/progenitor cells (NSPCs) hold great promise in regenerative medicine; however, controlling their differentiation to a desired phenotype within a defined matrix is challenging. To guide the differentiation of NSPCs, we first created a cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d28c464ae56a96035a353ea0a7f4ba
https://doi.org/10.1016/j.biomaterials.2008.08.018
https://doi.org/10.1016/j.biomaterials.2008.08.018
Autor:
Tasneem Zahir, Molly S. Shoichet, Howard Kim, Yusuke Katayama, Charles H. Tator, Hiroshi Nomura, Iris Kulbatski, Cindi M. Morshead
Publikováno v:
Tissue Engineering Part A. 14:649-665
Transplantation of neural stem and progenitor cells (NSPCs) is a promising strategy for repair after spinal cord injury. However, the epicenter of the severely damaged spinal cord is a hostile environment that results in poor survival of the transpla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e64c16d46d151653fbe8994419f38833
https://doi.org/10.1089/tea.2007.0180
https://doi.org/10.1089/tea.2007.0180
Publikováno v:
Biomacromolecules. 9:166-174
Polymeric assemblies are used in many biomaterials applications, ranging from drug-bearing nanoparticles to macroscopic scaffolds. Control over their biodegradation rates is usually achieved through synthetic modification of their molecular structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f5eec33cd2335d280f11caf3b22ba9
https://doi.org/10.1021/bm7009416
https://doi.org/10.1021/bm7009416
Publikováno v:
Biomaterials. 34(15)
Traumatic injury to the spinal cord causes cell death, demyelination, axonal degeneration, and cavitation resulting in functional motor and sensory loss. Stem cell therapy is a promising approach for spinal cord injury (SCI); however, this strategy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d3d527da407069997f6987915032624
https://pubmed.ncbi.nlm.nih.gov/23465486
https://pubmed.ncbi.nlm.nih.gov/23465486
Autor:
Tasneem Zahir, Cindi M. Morshead, Xiaodong Guo, Andrea J. Mothe, Yusuke Katayama, Charles H. Tator, Molly S. Shoichet
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Adult central mammalian axons show minimal regeneration after spinal cord injury due to loss of oligodendrocytes, demyelination of surviving axons, absence of growth-promoting molecules, and inhibitors of axonal outgrowth. In the present study, we at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dca1bfde1d16a56af3b70a1d6dbdf36
https://doaj.org/article/10cd97e537bd4e3ea57fa38a787cd71d
https://doaj.org/article/10cd97e537bd4e3ea57fa38a787cd71d