Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Tasneem Bawa"'
Autor:
Maram Quttina, Kacie D. Waiters, Ashfia Fatima Khan, Samaneh Karami, Anthony S. Peidl, Mariam Funmi Babajide, Justus Pennington, Fatima A. Merchant, Tasneem Bawa-Khalfe
Publikováno v:
Cells, Vol 12, Iss 20, p 2495 (2023)
Long, noncoding RNAs (lncRNAs) are indispensable for normal cell physiology and, consequently, are tightly regulated in human cells. Yet, unlike mRNA, substantially less is known about the mechanisms for lncRNA degradation. It is important to delinea
Externí odkaz:
https://doaj.org/article/4f80b998c2a446d0b7c3e3f4306a9ce8
Autor:
Shaymaa Bahnassy, Hariprasad Thangavel, Maram Quttina, Ashfia Fatima Khan, Dhanya Dhanyalayam, Joan Ritho, Samaneh Karami, Jing Ren, Tasneem Bawa-Khalfe
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Abstract Background Hormone receptor positive (HR+) breast cancer (BCa) is the most frequently diagnosed subtype. Acquired and intrinsic resistance to conventional endocrine therapy (ET) commonly occurs and prompts incurable metastatic disease. Hence
Externí odkaz:
https://doaj.org/article/d4aaf94611524f299995bd2d53354d77
Autor:
Asitha Premaratne, Charles Ho, Shinjini Basu, Ashfia Fatima Khan, Tasneem Bawa-Khalfe, Chin-Yo Lin
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 345 (2023)
Liver X receptors (LXRs) are members of the nuclear receptor family of ligand-dependent transcription factors which regulate the expression of lipid and cholesterol metabolism genes. Moreover, LXRs and their ligands have been shown to inhibit tumor g
Externí odkaz:
https://doaj.org/article/2f8e6b7dfba94a36b1e587382e3d2b8f
Autor:
Muhammad S. Moolla, Arifa Parker, Mohammed A. Parker, Sthembiso Sithole, Leila Amien, Rubeena Chiecktey, Tasneem Bawa, Abdurasiet Mowlana
Publikováno v:
Southern African Journal of Infectious Diseases, Vol 36, Iss 1, Pp e1-e5 (2021)
Background: Healthcare workers are at increased risk of contracting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potentially causing institutional outbreaks. Staff testing is critical in identifying and isolating infected individu
Externí odkaz:
https://doaj.org/article/b7d24dd14724425d8a38eefb5d4fe8ea
Publikováno v:
Cell Reports, Vol 15, Iss 1, Pp 147-157 (2016)
Origin recognition complex 2 (ORC2), a subunit of the ORC, is essential for DNA replication initiation in eukaryotic cells. In addition to a role in DNA replication initiation at the G1/S phase, ORC2 has been shown to localize to the centromere durin
Externí odkaz:
https://doaj.org/article/3f900830780f4ed8bc000a451c3ee919
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 8, Pp 667-676 (2006)
SUMO is a novel ubiquitin-like protein that can covalently modify a large number of nuclear proteins. SUMO modification has emerged as an important regulatory mechanism for protein function and localization. Sumoylation is a dynamic process that is m
Externí odkaz:
https://doaj.org/article/3ec27d24b0984ecf97a0c924a9b9e2e7
Autor:
Sandra L. Grimm, Guowei Gu, Sarah K. Herzog, Thomas L. Gonzalez, Hangqing Lin, Amanda R. Beyer, Yassine Rechoum, Tasneem Bawa-Khalfe, Ashfia F. Khan, Lili Du, W. Fraser Symmans, Ralf Kittler, Cristian Coarfa, Suzanne A.W. Fuqua
Publikováno v:
Cancer Research. 82:PD1-07
Background: Acquired ESR1 mutations are a dominant driver of distant metastasis in metastatic breast cancer, inducing a basal-like phenotype that is relatively resistant to ER antagonists with decreased progression free survival. The majority of ER+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943b176fbd5f57b73ecf1d90e7f894aa
https://doi.org/10.1158/1538-7445.sabcs21-pd1-07
https://doi.org/10.1158/1538-7445.sabcs21-pd1-07
Autor:
Shaymaa Bahnassy, Tasneem Bawa-Khalfe, Dhanya Dhanyalayam, Samaneh Karami, Jing Ren, Ashfia Fatima Khan, Joan Ritho, Maram Quttina, Hariprasad Thangavel
Publikováno v:
Cancer Research. 81:PS17-33
Background: Conventional endocrine therapy is the first-line treatment for hormone receptor positive (HR+) breast cancer (BCa) subtype. Frequently, intrinsic and acquired ET resistance (ET-R) persists to support a disease with poor prognosis and limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18d9746f65417a71e7aa091c5888417d
https://doi.org/10.1158/1538-7445.sabcs20-ps17-33
https://doi.org/10.1158/1538-7445.sabcs20-ps17-33
Autor:
Hiroyuki Katayama, Alastair M. Thompson, Aysegul A. Sahin, Kazuharu Kai, Tasneem Bawa-Khalfe, Kwong Kwok Wong, Luisa M. Solis, CM Abbott, Ignacio I. Wistuba, W Tian, David H. Hawke, L Qin, Kaori Sasai, Roland Rad, Shiraj Sen, Warapen Treekitkarnmongkol, Jonathan M. Lee, Y Jltsumori
Publikováno v:
Cancer Research. 79:P1-05
The AURKA gene, encoding Aurora kinase-A (Aurora-A), is frequently amplified and overexpressed across multiple cancer types correlating with poor prognosis. Although the AURKA gene is frequently amplified in human cancers, underlying mechanism(s) for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::688f8c4579f20c63f7f8c655d2892654
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-05
https://doi.org/10.1158/1538-7445.sabcs18-p1-05-05
Autor:
Hariprasad Thangavel, Samaneh Karami, Dhanya Dhanyalayam, Tasneem Bawa-Khalfe, Jing Ren, Maram Quttina, Ashfia Fatima Khan, Shaymaa Bahnassy, Joan Ritho
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-11 (2020)
Background Hormone receptor positive (HR+) breast cancer (BCa) is the most frequently diagnosed subtype. Acquired and intrinsic resistance to conventional endocrine therapy (ET) commonly occurs and prompts incurable metastatic disease. Hence, ET-resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b723a8fffef16ab0bd0ecb1fcf72ebe7
https://doi.org/10.1186/s12964-020-00649-z
https://doi.org/10.1186/s12964-020-00649-z