Výsledky vyhledávání - "Tasmiyah Khan"

Imidazo[1,2-a]pyridin-3-amines as potential HIV-1 non-nucleoside reverse transcriptase inhibitors

Autor: Heinrich C. Hoppe, Simon Sana Moleele, Paul A. Steenkamp, David Gravestock, Lindiwe A. Nkabinde, Tasmiyah Khan, Stephen C. Pelly, Moira L. Bode, Christiaan W. van der Westhuyzen

Publikováno v: Bioorganic & Medicinal Chemistry. 19:4227-4237

During random screening of a small in-house library of compounds, certain substituted imidazo[1,2- a ]pyridines were found to be weak allosteric inhibitors of HIV-1 reverse transcriptase (RT). A library of these compounds was prepared using the Groeb

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b885cc886bd56959b7165a891038c50
https://doi.org/10.1016/j.bmc.2011.05.062

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ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum

Autor: Tasmiyah Khan, Christopher J. Parkinson, Heinrich C. Hoppe, Anna C van Brummelen

Publikováno v: Charles Sturt University
Malaria Journal, Vol 11, Iss 1, p 369 (2012)
Malaria Journal

Background Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely in vivo parasite clearance rates in order to sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d64ed2538868f8ec3b270d255f0239
https://doi.org/10.1186/1475-2875-11-369

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