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pro vyhledávání: '"Tashika Harris"'
Autor:
Xi Yang, Thomas Papoian, Matthew White, Qiangen Wu, James Greenhaw, Tashika Harris, Lijun Ren, Jun Zhang, Matthew Bryant, Qiang Shi, William B. Mattes
Publikováno v:
Toxicology Letters. 291:138-148
Of the 34 FDA approved oral small-molecule kinase inhibitors (KI), 23 (68%) have warnings for hepatotoxicity in product labeling. To better understand the mechanisms of KI hepatotoxicity and whether such effects can be predicted, we examined 34 KIs f