Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tasha L. Lin"'
Autor:
Amit Kumar Jaiswal, Hellen Truong, Tiffany M. Tran, Tasha L. Lin, David Casero, Michael O. Alberti, Dinesh S. Rao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Post-transcriptional gene regulation, including that by RNA binding proteins (RBPs), has recently been described as an important mechanism in cancer. We had previously identified a set of RBPs that were highly dysregulated in B-cell acute ly
Externí odkaz:
https://doaj.org/article/21414bf1581e42608d925e918106ab1e
Autor:
Tasha L. Lin, Tiffany M. Tran, David Casero, Dinesh S. Rao, Amit Kumar Jaiswal, Michael O. Alberti, Hellen Truong
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific reports, vol 11, iss 1
Post-transcriptional gene regulation, including that by RNA binding proteins (RBPs), has recently been described as an important mechanism in cancer. We had previously identified a set of RBPs that were highly dysregulated in B-cell acute lymphoblast
Autor:
Oscar Silva, J. King, May Paing, Julia Philipp, Dinesh S. Rao, Tasha L. Lin, Tiffany M. Tran, Jaspal Bassi, Sol Katzman, Jeremy R. Sanford, Amit Kumar Jaiswal, Jolene M. Draper, Neha Nibber, Jayanth Kumar Palanichamy
Publikováno v:
Leukemia, vol 36, iss 1
Leukemia
Leukemia
Despite recent advances in therapeutic approaches, patients with MLL-rearranged leukemia still have poor outcomes. Here, we find that the RNA-binding protein IGF2BP3, which is overexpressed in MLL-translocated leukemia, strongly amplifies MLL-Af4-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5597ab10bcdee8f0c9f1537a25fd07
https://escholarship.org/uc/item/5wr144fv
https://escholarship.org/uc/item/5wr144fv
Publikováno v:
Cancer Research. 72:3502-3502
Clinical trials of T cells genetically engineered to express chimeric antigen receptors (CAR) are currently underway for multiple malignancies with encouraging results. However, much work remains to be done to optimize CAR T cell therapy with a press