Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Tasha K. Ritchie"'
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
As the research into the organic anion transporting polypeptides (OATPs) continues to grow, it is important to ensure that the data generated are accurate and reproducible. In the in vitro evaluation of OATP1B1/1B3 inhibition, there are many variable
Externí odkaz:
https://doaj.org/article/c3c9836c44de46e1ae64bd2db604ee3c
Autor:
Savannah J. McFeely, Tasha K. Ritchie, Jingjing Yu, Anna Nordmark, René H. Levy, Isabelle Ragueneau‐Majlessi
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 4, Pp 379-387 (2019)
Organic anion transporting polypeptides (OATPs) 1B1 and 1B3 facilitate the uptake of drugs and endogenous compounds into the liver. In recent years, the impact of these transporters on drug–drug interactions (DDIs) has become a focus of research, a
Externí odkaz:
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
Autor:
Anna Nordmark, Tasha K. Ritchie, Isabelle Ragueneau-Majlessi, Eva Gil Berglund, Jingjing Yu, Savannah J. McFeely
Publikováno v:
Clinical and Translational Science, Vol 12, Iss 4, Pp 379-387 (2019)
Clinical and Translational Science
Clinical and Translational Science
Organic anion transporting polypeptides (OATPs) 1B1 and 1B3 facilitate the uptake of drugs and endogenous compounds into the liver. In recent years, the impact of these transporters on drug–drug interactions (DDIs) has become a focus of research, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e6014d4b0b76772f54805b319eb565
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
https://doaj.org/article/4ae2f0f225db460998f21e67cfee0c27
Publikováno v:
Pharmacology & Therapeutics. 196:204-215
The importance of uptake transporters in determining drug disposition is increasingly appreciated. While the focus of regulatory agencies worldwide has been on the hepatic organic anion transporting polypeptides (OATPs)—1B1 and—1B3, there is anot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed318ea358719cf83105760991882e2
https://doi.org/10.1016/j.pharmthera.2018.12.009
https://doi.org/10.1016/j.pharmthera.2018.12.009
Autor:
Tasha K. Ritchie, Savannah J. McFeely, Isabelle Ragueneau-Majlessi, René H. Levy, Anna Nordmark, Jingjing Yu, Eva Gil Berglund
Publikováno v:
Journal of clinical pharmacologyReferences. 60(8)
Organic anion-transporting polypeptides (OATPs) 1B1 and 1B3 are the primary hepatic transporters responsible for uptake of drugs into the liver and, as such, an area of growing research focus. Currently, evaluation of these transporters as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65139b6c336a9c76118af513add187de
https://pubmed.ncbi.nlm.nih.gov/32196692
https://pubmed.ncbi.nlm.nih.gov/32196692
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
Clinical and Translational Science, Vol 13, Iss 1, Pp 47-52 (2020)
As the research into the organic anion transporting polypeptides (OATPs) continues to grow, it is important to ensure that the data generated are accurate and reproducible. In the in vitro evaluation of OATP1B1/1B3 inhibition, there are many variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffdb61130348ce4caa2dfdde82e685d
https://pubmed.ncbi.nlm.nih.gov/31468718
https://pubmed.ncbi.nlm.nih.gov/31468718
Publikováno v:
Drug Metabolism and Disposition. 45:86-108
As a follow up to previous reviews, the aim of the present analysis was to systematically examine all drug metabolism, transport, pharmacokinetics (PK), and drug-drug interaction (DDI) data available in the 33 new drug applications (NDAs) approved by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0274e398f4e07dbf5f0f7aa11f0604de
https://doi.org/10.1124/dmd.116.073411
https://doi.org/10.1124/dmd.116.073411
Publikováno v:
Drug Metabolism and Pharmacokinetics. 35:S94
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff65558c566a68c850825b65bf729b44
https://doi.org/10.1016/j.dmpk.2020.04.238
https://doi.org/10.1016/j.dmpk.2020.04.238
Publikováno v:
Drug Metabolism and Disposition. 44:83-101
Regulatory approval documents contain valuable information, often not published, to assess the drug-drug interaction (DDI) profile of newly marketed drugs. This analysis aimed to systematically review all drug metabolism, transport, pharmacokinetics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fab51693d2a284d27dbd445a2a6c8e
https://doi.org/10.1124/dmd.115.066720
https://doi.org/10.1124/dmd.115.066720
Autor:
Harma Ellens, Mary F. Paine, Maciej J. Zamek-Gliszczynski, Jack Cook, Caroline A. Lee, Mitchell E. Taub, Tasha K. Ritchie, Joseph A. Ware, Bo Feng, Meeghan A O'Connor, Aleksandra Galetin, Isabelle Ragueneau-Majlessi, Joseph W. Polli
Publikováno v:
Drug Metabolism and Disposition. 43:490-509
Breast cancer resistance protein (BCRP; ABCG2) limits intestinal absorption of low-permeability substrate drugs and mediates biliary excretion of drugs and metabolites. Based on clinical evidence of BCRP-mediated drug-drug interactions (DDIs) and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a06f6950d0467683ba7779ef8a23e0
https://doi.org/10.1124/dmd.114.062174
https://doi.org/10.1124/dmd.114.062174