WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues

Autor: Gaertner, Florian, Reis-Rodrigues, Patricia, de Vries, Ingrid, Hons, Miroslav, Aguilera, Juan, Riedl, Michael, Leithner, Alexander, Tasciyan, Saren, Kopf, Aglaja, Merrin, Jack, Zheden, Vanessa, Kaufmann, Walter Anton, Hauschild, Robert, Sixt, Michael

Publikováno v: In Developmental Cell 10 January 2022 57(1):47-62

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The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection

Autor: Ebner, Florian, Sedlyarov, Vitaly, Tasciyan, Saren, Ivin, Masa, Kratochvill, Franz, Gratz, Nina, Kenner, Lukas, Villunger, Andreas, Sixt, Michael, Kovarik, Pavel

Protective responses against pathogens require a rapid mobilization of resting neutrophils and the timely removal of activated ones. Neutrophils are exceptionally short-lived leukocytes, yet it remains unclear whether the lifespan of pathogen-engaged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b9c8fd63ec3f37acf60120107e385a4f
https://europepmc.org/articles/PMC5451238/

The RNA-binding protein tristetraprolin schedules apoptosis of pathogen-engaged neutrophils during bacterial infection.

Autor: Ebner F; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria., Sedlyarov V; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria., Tasciyan S; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria., Ivin M; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria., Kratochvill F; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria., Gratz N; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria., Kenner L; Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria.; Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.; Unit of Pathology of Laboratory Animals (UPLA), University of Veterinary Medicine Vienna, Vienna, Austria., Villunger A; Medical University of Innsbruck, Division of Developmental Immunology, Innsbruck, Austria.; Tyrolean Cancer Research Institute, Innsbruck, Austria., Sixt M; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria., Kovarik P; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2017 Jun 01; Vol. 127 (6), pp. 2051-2065. Date of Electronic Publication: 2017 May 15.