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pro vyhledávání: '"Tasaduq H. Wani"'
Publikováno v:
Biomolecules, Vol 12, Iss 7, p 864 (2022)
Molecular chaperones such as Hsp70 and Hsp90 help fold and activate proteins in important signal transduction pathways that include DNA damage response (DDR). Previous studies have suggested that the levels of the mammalian APE2 exonuclease, a protei
Externí odkaz:
https://doaj.org/article/e5fc1fdeed1941f3ac2fb2a6a48dd9d8
Publikováno v:
Cell Stress Chaperones
The ER-resident Hsp70 paralog BiP is important in cellular homeostasis as well as in cancer cell progression. Although several BiP inhibitors have been developed, they have not succeeded in clinical trials due to toxicity issues. ER-resident co-chape