Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Taryn N. Green"'
Autor:
Christopher Puli'uvea, Tracey Immanuel, Taryn N. Green, Peter Tsai, Peter R. Shepherd, Maggie L. Kalev-Zylinska
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTObjectives: This study aimed to compile bioinformatic and experimental information for JAK2 missense variants previously reported in myeloproliferative neoplasms (MPN) and determine if germline JAK2-I724T, recently found to be common in New Z
Externí odkaz:
https://doaj.org/article/ce5b4c33076141b4ba8b6008985068fb
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Intracellular calcium signaling regulates diverse physiological and pathological processes. In solid tumors, changes to calcium channels and effectors via mutations or changes in expression affect all cancer hallmarks. Such changes often disrupt tran
Externí odkaz:
https://doaj.org/article/db30d79531af4374b2f3a147e31793bc
Autor:
Taryn N. Green, Justin R. Hamilton, Marie-Christine Morel-Kopp, Zhaohua Zheng, Ting-Yu T. Chen, James I. Hearn, Peng P. Sun, Jack U. Flanagan, Deborah Young, P. Alan Barber, Matthew J. During, Christopher M. Ward, Maggie L. Kalev-Zylinska
Publikováno v:
Platelets, Vol 28, Iss 8, Pp 799-811 (2017)
GluN1 is a mandatory component of N-methyl-D-aspartate receptors (NMDARs) best known for their roles in the brain, but with increasing evidence for relevance in peripheral tissues, including platelets. Certain anti-GluN1 antibodies reduce brain infar
Externí odkaz:
https://doaj.org/article/777a1eb7851b450190f5c33b151b9622
Autor:
Young Eun Park, Rushi Penumarthy, Paul P. Sun, Caroline Y. Kang, Marie-Christine Morel-Kopp, Jonathan Downing, Taryn N. Green, Tracey Immanuel, Christopher M. Ward, Deborah Young, Matthew J. During, P. Alan Barber, Maggie L. Kalev-Zylinska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8398 (2020)
Ischaemic brain damage induces autoimmune responses, including the production of autoantibodies with potential neuroprotective effects. Platelets share unexplained similarities with neurons, and the formation of anti-platelet antibodies has been docu
Externí odkaz:
https://doaj.org/article/d6fe794e0c7648f7bb8dab6be13af2c5
Autor:
James I. Hearn, Taryn N. Green, Colin L. Hisey, Markus Bender, Emma C. Josefsson, Nicholas Knowlton, Juliane Baumann, Raewyn C. Poulsen, Stefan K. Bohlander, Maggie L. Kalev-Zylinska
Publikováno v:
Blood. 139:2673-2690
The process of proplatelet formation (PPF) requires coordinated interaction between megakaryocytes (MKs) and the extracellular matrix (ECM), followed by a dynamic reorganization of the actin and microtubule cytoskeleton. Localized fluxes of intracell
Autor:
Valery Yizhuo Liu, Nicole Chien, Taryn N. Green, Chris Varghese, Maggie L. Kalev-Zylinska, Tracey Immanuel, Edward Theakston, George Chan
Publikováno v:
Hematology. 26:215-224
Ethnic differences in haematologic malignancies remain poorly elucidated, hence research in this area is important. This was a retrospective study into potential ethnic disparity in the presentation and outcomes of acute promyelocytic leukaemia (APL)
Autor:
Cherie Blenkiron, Stefan K. Bohlander, Maggie L. Kalev-Zylinska, Nicholas Knowlton, Taryn N. Green, Raewyn C. Poulsen, James I. Hearn, Yohanes Nursalim, Leandro Ladvanszky, Dean C. Singleton, Martin Chopra
Publikováno v:
Thrombosis and Haemostasis
The release of calcium ions (Ca2+) from the endoplasmic reticulum (ER) and related store-operated calcium entry (SOCE) regulate maturation of normal megakaryocytes. The N-methyl-D-aspartate (NMDA) receptor (NMDAR) provides an additional mechanism for
Autor:
George Chan, Nicole Chien, Peter Browett, Nicola Eaddy, Tim E. Hawkins, Edward Theakston, Richard Doocey, Taryn N. Green, Leanne Berkahn, Chris Varghese, Maggie L. Kalev-Zylinska
Publikováno v:
Leukemia research. 93
All-trans retinoic acid (ATRA) and arsenic trioxide (ATO) are effective induction therapy for acute promyelocytic leukaemia (APL). However, early thrombo-haemorrhagic complications and mortality remain high. We aimed to investigate how the timing of
Autor:
Hannah O Ajoge, Michelle L Gordon, Tulio de Oliveira, Taryn N Green, Sani Ibrahim, Oladapo S Shittu, Stephen O Olonitola, Aliyu A Ahmad, Thumbi Ndung'u
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17865 (2011)
HIV-1 CRF02_AG and subtype G (HIV-1G) account for most HIV infections in Nigeria, but their evolutionary trends have not been well documented. To better elucidate the dynamics of the epidemic in Nigeria we characterised the gag and env genes of North
Externí odkaz:
https://doaj.org/article/f1351e02aa434bbdb1b10344ad2ab711
Autor:
James I. Hearn, Marie-Christine Morel-Kopp, Tania Kamal, Taryn N. Green, Matthew J. During, Maggie L. Kalev-Zylinska, Chris Ward, Emma C. Josefsson
Publikováno v:
Research and Practice in Thrombosis and Haemostasis
Essentials Intracellular calcium pathways regulate megakaryopoiesis but details are unclear.We examined effects of NMDAR‐mediated calcium influx on normal and leukemic cells in culture.NMDARs facilitated differentiation of normal but proliferation