Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Taryn J. Earley"'
Publikováno v:
Neuron. 64:498-509
SummaryTransient receptor potential A1 (TRPA1) ion channel senses a variety of noxious stimuli and is involved in nociception. Many TRPA1 agonists covalently modify the channel, which can lead to desensitization. The fate of modified TRPA1 and the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a589f0e63f948b785f38ead9009d9b9
https://doi.org/10.1016/j.neuron.2009.09.030
https://doi.org/10.1016/j.neuron.2009.09.030
Publikováno v:
The Journal of Neuroscience. 28:566-575
Environmental stimuli such as temperature and pressure are sensed by dorsal root ganglion (DRG) neurons. DRG neurons are heterogeneous, but molecular markers that identify unique functional subpopulations are mainly lacking. ThermoTRPs are members of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218dbbcb8f55d833221818c2e6fb4d4a
https://doi.org/10.1523/jneurosci.3976-07.2008
https://doi.org/10.1523/jneurosci.3976-07.2008
Autor:
Michael Zhao, Clifford J. Woolf, Colby A. Cook, Donato del Camino, Matt Petrus, Christopher M. Fanger, Marc D'Amours, Ardem Patapoutian, Michael Costigan, Sarah Murphy, Melissa Heiry, Neil Hayward, Nate Deering, Magdalene M. Moran, Gary J. Brenner, Jayhong A. Chong, Lee Barrett, Taryn J. Earley
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 30(45)
TRPA1 is a nonselective cation channel expressed by nociceptors. Although it is widely accepted that TRPA1 serves as a broad irritancy receptor for a variety of reactive chemicals, its role in cold sensation remains controversial. Here, we demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47bbe6c4f5508850b8aee6ab9f1ea4b2
https://pubmed.ncbi.nlm.nih.gov/21068322
https://pubmed.ncbi.nlm.nih.gov/21068322
Autor:
Jayanti Mathur, Adrienne E. Dubin, Ardem Patapoutian, Manuela Schmidt, Sanjeev S. Ranade, Matt Petrus, Taryn J. Earley, Bertrand Coste
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2010, 330 (6000), pp.55-60. ⟨10.1126/science.1193270⟩
Science, 2010, 330 (6000), pp.55-60. ⟨10.1126/science.1193270⟩
Science, American Association for the Advancement of Science, 2010, 330 (6000), pp.55-60. ⟨10.1126/science.1193270⟩
Science, 2010, 330 (6000), pp.55-60. ⟨10.1126/science.1193270⟩
Mechanical Responders Identified Although many cells appear to respond to mechanical stimulation through increased conductance of ion channels in the plasma membrane, the actual channels that mediate these effects—which are important in diverse pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce2c84c873039ddcf0ce36fe3285273
https://hal-amu.archives-ouvertes.fr/hal-03464348
https://hal-amu.archives-ouvertes.fr/hal-03464348
Autor:
Ardem Patapoutian, Sun Wook Hwang, Matt J. Petrus, Amber N. Murray, Taryn J. Earley, Kathryn S. R. Spencer, Aziz Moqrich, Mary Andahazy, Gina M. Story
Publikováno v:
Science (New York, N.Y.). 307(5714)
Environmental temperature is thought to be directly sensed by neurons through their projections in the skin. A subset of the mammalian transient receptor potential (TRP) family of ion channels has been implicated in this process. These “thermoTRPs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8df57efb2da111190582070c6b1626
https://pubmed.ncbi.nlm.nih.gov/15746429
https://pubmed.ncbi.nlm.nih.gov/15746429
Autor:
Douglas E. Wright, Taryn J. Earley, Louis F. Reichardt, James Watson, Ardem Patapoutian, Dionisio Martin-Zanca, Mary Andahazy, Aziz Moqrich, Carey Backus
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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instname
El pdf del artículo es el manuscrito de autor.-- et al.
Tactile information is perceived by a heterogeneous population of specialized neurons. Neurotrophin receptors (the receptor tyrosine kinases, Trks) mark the major classes of these sensory
Tactile information is perceived by a heterogeneous population of specialized neurons. Neurotrophin receptors (the receptor tyrosine kinases, Trks) mark the major classes of these sensory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d84260320d038257b87331f525991fa7
https://pubmed.ncbi.nlm.nih.gov/15247919
https://pubmed.ncbi.nlm.nih.gov/15247919
Autor:
Andrea M. Peier, Alison J. Reeve, John B. Hogenesch, David Andersson, Peter McIntyre, Gina M. Story, Sian Colley, Ardem Patapoutian, Stuart Bevan, Taryn J. Earley, Anne C. Hergarden, Aziz Moqrich
Publikováno v:
Science (New York, N.Y.). 296(5575)
Mechanical and thermal cues stimulate a specialized group of sensory neurons that terminate in the skin. Three members of the transient receptor potential (TRP) family of channels are expressed in subsets of these neurons and are activated at distinc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57944d8c06824b184625014f1d63e469
https://pubmed.ncbi.nlm.nih.gov/12016205
https://pubmed.ncbi.nlm.nih.gov/12016205
Autor:
Ilaria Dragoni, Alison J. Reeve, Peter McIntyre, Andrea M. Peier, David Andersson, Ardem Patapoutian, Gina M. Story, Stuart Bevan, Anne C. Hergarden, Aziz Moqrich, Taryn J. Earley
Publikováno v:
Cell. 108(5)
A distinct subset of sensory neurons are thought to directly sense changes in thermal energy through their termini in the skin. Very little is known about the molecules that mediate thermoreception by these neurons. Vanilloid Receptor 1 (VR1), a memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695043496e1b8a6b6e290dbf70e9e0c9
https://pubmed.ncbi.nlm.nih.gov/11893340
https://pubmed.ncbi.nlm.nih.gov/11893340
Autor:
Gina M. Story, Samer R. Eid, Ardem Patapoutian, Veena Viswanath, Taryn J. Earley, Michael Bandell, Sun Wook Hwang, Matt Petrus
Publikováno v:
Neuron. (6):849-857
Six members of the mammalian transient receptor potential (TRP) ion channels respond to varied temperature thresholds. The natural compounds capsaicin and menthol activate noxious heat-sensitive TRPV1 and cold-sensitive TRPM8, respectively. The burni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8800346bd9733ee1a6cc8cf36d243364
Autor:
Samer R. Eid, Timothy Jegla, Taryn J. Earley, Andrea M. Peier, Anne C. Hergarden, Alison J. Reeve, Stuart Bevan, David Andersson, Peter McIntyre, Gina M. Story, Ardem Patapoutian, Sun Wook Hwang, Johannes Mosbacher, Todd R. Hricik
Publikováno v:
Cell. (6):819-829
Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been implicated in sensing heat, and one TRPM-class channel in sensing cold. The combined range of temperatures that activate these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de512d65f586f8746913d57e9efe6831