Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Taryn E. Mockus"'
Autor:
Shwetank, Elizabeth L. Frost, Taryn E. Mockus, Heather M. Ren, Mesut Toprak, Matthew D. Lauver, Colleen S. Netherby-Winslow, Ge Jin, Jennifer M. Cosby, Brian D. Evavold, Aron E. Lukacher
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Programmed cell death-1 (PD-1) receptor signaling dampens the functionality of T cells faced with repetitive antigenic stimulation from chronic infections or tumors. Using intracerebral (i.c.) inoculation with mouse polyomavirus (MuPyV), we have show
Externí odkaz:
https://doaj.org/article/2285a3c6a6f249b79551624c67d00b1d
Publikováno v:
Viruses, Vol 11, Iss 9, p 842 (2019)
CD8 T cells coordinate immune defenses against viral infections of the central nervous system (CNS). Virus-specific CD8 T cells infiltrate the CNS and differentiate into brain-resident memory CD8 T cells (CD8 bTRM). CD8 bTRM are characterized by a la
Externí odkaz:
https://doaj.org/article/ce15205c60b4473da2f18fb3c3f5398c
Autor:
Taryn E Mockus, Shwetank, Matthew D Lauver, Heather M Ren, Colleen S Netherby, Tarik Salameh, Yuka Imamura Kawasawa, Feng Yue, James R Broach, Aron E Lukacher
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007365 (2018)
Tissue-resident memory CD8 T (TRM) cells defend against microbial reinfections at mucosal barriers; determinants driving durable TRM cell responses in non-mucosal tissues, which often harbor opportunistic persistent pathogens, are unknown. JC polyoma
Externí odkaz:
https://doaj.org/article/cb8d4d6b30ac4975a39ef86c1ea04ee5
Publikováno v:
J Immunol
Multiple sclerosis (MS), a neuroinflammatory disease that affects millions worldwide, is widely thought to be autoimmune in etiology. Historically, research into MS pathogenesis has focused on autoreactive CD4 T cells because of their critical role i
Autor:
Nancy J. Olsen, Hannah M Atkins, Sathi Babu Chodisetti, Chelsea Corradetti, Adam J. Fike, Taryn E. Mockus, Zia Ur Rahman, Thomas Decker, Phillip P. Domeier, Nicholas M Choi, Stephanie L. Schell, Aron E. Lukacher, Roberto Caricchio, Baidong Hou
Publikováno v:
J Immunol
Although STAT1 tyrosine-701 phosphorylation (designated STAT1-pY701) is indispensable for STAT1 function, the requirement for STAT1 serine-727 phosphorylation (designated STAT1-pS727) during systemic autoimmune and antipathogen responses remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35cdd6b68199661ab1354b1d9833317
https://europepmc.org/articles/PMC9305983/
https://europepmc.org/articles/PMC9305983/
Autor:
Heather M. Ren, Ge Jin, Colleen S. Netherby-Winslow, Taryn E. Mockus, Hannah M Atkins, Matthew D. Lauver, Aron E. Lukacher
Publikováno v:
J Virol
JC polyomavirus (JCPyV), a human-specific virus, causes the aggressive brain-demyelinating disease progressive multifocal leukoencephalopathy (PML) in individuals with depressed immune status. The increasing incidence of PML in patients receiving imm
Autor:
Elizabeth L. Frost, Shwetank, Heather M. Schmitz, Taryn E. Mockus, Hossam A. Abdelsamed, Aron E. Lukacher, Ben Youngblood
Publikováno v:
Immunology and Cell Biology
Infection of the central nervous system (CNS) by murine polyomavirus (MuPyV), a persistent natural mouse pathogen, establishes brain-resident memory CD8 T cells (bTRM) that uniformly and chronically express programmed cell death protein 1 (PD-1) irre
Autor:
Colleen S. Netherby-Winslow, Mesut Toprak, Jennifer M. Cosby, Heather M. Ren, Taryn E. Mockus, Elizabeth L. Frost, Ge Jin, Brian D. Evavold, Matthew D. Lauver, Shwetank, Aron E. Lukacher
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
Programmed cell death-1 (PD-1) receptor signaling dampens the functionality of T cells faced with repetitive antigenic stimulation from chronic infections or tumors. Using intracerebral (i.c.) inoculation with mouse polyomavirus (MuPyV), we have show
Autor:
James R. Broach, Colleen S. Netherby, Taryn E. Mockus, Heather M. Ren, Aron E. Lukacher, Tarik J. Salameh, Yuka Imamura Kawasawa, Feng Yue, Matthew D. Lauver, Shwetank
Publikováno v:
PLoS Pathogens, Vol 14, Iss 10, p e1007365 (2018)
PLoS Pathogens
PLOS Pathogens
PLoS Pathogens
PLOS Pathogens
Tissue-resident memory CD8 T (TRM) cells defend against microbial reinfections at mucosal barriers; determinants driving durable TRM cell responses in non-mucosal tissues, which often harbor opportunistic persistent pathogens, are unknown. JC polyoma
Publikováno v:
The Journal of Immunology. 196:55.21-55.21
JC polyomavirus (JCV), a common member of the virome in healthy humans, can cause the frequently fatal brain demyelinating disease Progressive Multifocal Leukoencephalopathy (PML) in immunocompromised individuals. PML, a pre-HAART AIDS-defining disea