Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Taryn A, Miner"'
Autor:
Muluneh M. Fashe, Taryn A. Miner, John K. Fallon, Amanda P. Schauer, Craig Sykes, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Pregnancy increases the clearance of CYP3A4 substrate drugs and pregnancy-related hormones (PRHs) induce hepatic CYP3A4 expression and metabolism. However, it remains unclear to what extent the magnitude of PRH-evoked changes in hepatic
Externí odkaz:
https://doaj.org/article/5bf5aea07c3d46e3afd836d8b7b04fe3
Autor:
Olga G. Ovchinnikova, Logan P. Treat, Tanisha Teelucksingh, Bradley R. Clarke, Taryn A. Miner, Chris Whitfield, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, in
Externí odkaz:
https://doaj.org/article/8357e1b51d36462e839941a564b8e951
Autor:
Muluneh M. Fashe, John K. Fallon, Taryn A. Miner, Jacqueline B. Tiley, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pregnancy alters the disposition and exposure to multiple drugs indicated for pregnancy-related complications. Previous in vitro studies have shown that pregnancy-related hormones (PRHs) alter the expression and function of certain cytochrome P450s (
Externí odkaz:
https://doaj.org/article/1e6c5b0acbba40869e4315e3c168bd86
Autor:
Raju Khatri, John K. Fallon, Craig Sykes, Natasha Kulick, Rebecca J. B. Rementer, Taryn A. Miner, Amanda P. Schauer, Angela D. M. Kashuba, Kim A. Boggess, Kim L. R. Brouwer, Philip C. Smith, Craig R. Lee
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pregnancy-related hormones (PRH) are recognized as important regulators of hepatic cytochrome P450 enzyme expression and function. However, the impact of PRH on the hepatic expression and function of uridine diphosphate glucuronosyltransferases (UGTs
Externí odkaz:
https://doaj.org/article/4cac6828a3614bad9e8e1bd1b1e4fcc3
Autor:
Kimberly A. Walker, Taryn A. Miner, Michelle Palacios, Dominika Trzilova, Daniel R. Frederick, Christopher A. Broberg, Victoria E. Sepúlveda, Joshua D. Quinn, Virginia L. Miller
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The polysaccharide capsule is an essential virulence factor for Klebsiella pneumoniae in both community-acquired hypervirulent strains as well as health care-associated classical strains that are posing significant challenges due to multidru
Externí odkaz:
https://doaj.org/article/d253aa4c055244b39986388f75d67fdc
Autor:
Michelle Palacios, Taryn A. Miner, Daniel R. Frederick, Victoria E. Sepulveda, Joshua D. Quinn, Kimberly A. Walker, Virginia L. Miller
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Klebsiella pneumoniae is widely recognized as a pathogen with a propensity for acquiring antibiotic resistance. It is capable of causing a range of hospital-acquired infections (urinary tract infections [UTI], pneumonia, sepsis) and communit
Externí odkaz:
https://doaj.org/article/f39045d829a44c37afed7e39105cd7c3
Publikováno v:
Journal of Bacteriology. 201
PsaA, the subunit of the fimbria originally referred to as the “pH 6 antigen,” is required for full virulence of Yersinia pestis during bubonic plague. The expression of psaA is dependent upon specific environmental signals, and while the signals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9691f27f17daf6a0f4b2a03fceea2e18
https://doi.org/10.1128/jb.00217-19
https://doi.org/10.1128/jb.00217-19
Autor:
Daniel R. Frederick, Victoria E. Sepúlveda, Kimberly A. Walker, Michelle Palacios, Dominika Trzilova, Virginia L. Miller, Taryn A. Miner, Christopher A. Broberg, Joshua D. Quinn
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
mBio, Vol 10, Iss 2, p e00089-19 (2019)
mBio
mBio, Vol 10, Iss 2, p e00089-19 (2019)
mBio
Klebsiella pneumoniae continues to be a substantial public health threat due to its ability to cause health care-associated and community-acquired infections combined with its ability to acquire antibiotic resistance. Novel therapeutics are needed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec21908567541af4926c34fed3c03910
https://doi.org/10.1128/mbio.00089-19
https://doi.org/10.1128/mbio.00089-19
Publikováno v:
Journal of Bacteriology
Y. pestis is a Gram-negative bacterial pathogen that causes bubonic plague. As a vector-borne pathogen, Y. pestis fluctuates between an arthropod vector (flea) and mammalian host. As such, Y. pestis must recognize environmental signals encountered wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::55c6602f0c0e9e579d095cd23bb43fb8
https://pubmed.ncbi.nlm.nih.gov/31138630
https://pubmed.ncbi.nlm.nih.gov/31138630