Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Tarsis F. Gesteira"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Various techniques using fluorescent reporter probes have been developed, such as GFP transgenic mouse lines that are used to detect spatial–temporal expression levels of genes. Although GFP expression is largely considered non-toxic, rece
Externí odkaz:
https://doaj.org/article/a2dab7df0da4440b8c710ea357988976
Autor:
Winston W. Y. Kao, Jianhua Zhang, Jhuwala Venkatakrishnan, Shao-Hsuan Chang, Yong Yuan, Osamu Yamanaka, Ying Xia, Tarsis F. Gesteira, Sudhir Verma, Vivien J. Coulson-Thomas, Chia-Yang Liu
Publikováno v:
Cells, Vol 13, Iss 19, p 1599 (2024)
The synthetic peptide of lumican C-terminal 13 amino acids with the cysteine replaced by an alanine, hereafter referred to as lumikine (LumC13C-A: YEALRVANEVTLN), binds to TGFβ type I receptor/activin-like kinase5 (TBR1/ALK5) in the activated TGFβ
Externí odkaz:
https://doaj.org/article/edf81ec16f7c43ccb0e1b8e2f51c11a5
Publikováno v:
Cells, Vol 13, Iss 13, p 1105 (2024)
The cornea is continuously exposed to injuries, ranging from minor scratches to deep traumas. An effective healing mechanism is crucial for the cornea to restore its structure and function following major and minor insults. Transforming Growth Factor
Externí odkaz:
https://doaj.org/article/6d685a1590a34b4e8324862e30ae37b6
Autor:
Sudan Puri, Isabel Y. Moreno, Mingxia Sun, Sudhir Verma, Xiao Lin, Tarsis F. Gesteira, Vivien J. Coulson-Thomas
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-21 (2022)
Abstract Background Hyaluronan (HA) has previously been identified as an integral component of the limbal stem cell niche in vivo. In this study, we investigated whether a similar HA matrix is also expressed in vitro providing a niche supporting limb
Externí odkaz:
https://doaj.org/article/3f757711185c46278d523479d8d336ca
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1385 (2023)
A buildup of reactive oxygen species (ROS) occurs in virtually all pathological conditions. Hyaluronan (HA) is a major extracellular matrix component and is susceptible to oxidation by reactive oxygen species (ROS), yet the precise chemical structure
Externí odkaz:
https://doaj.org/article/6adcde4d5fb345f5b4f2414e08b9ab7b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/8b9319a6fe214a18aaa44170b037763a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The ocular surface, which forms the interface between the eye and the external environment, includes the cornea, corneoscleral limbus, the conjunctiva and the accessory glands that produce the tear film. Glycosaminoglycans (GAGs) and proteoglycans (P
Externí odkaz:
https://doaj.org/article/836a7bedea6b44d28b1ca6c793484d83
Autor:
Kazadi N. Mutoji, Mingxia Sun, Garrett Elliott, Isabel Y. Moreno, Clare Hughes, Tarsis F. Gesteira, Vivien J. Coulson-Thomas
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5708 (2021)
Corneal transparency relies on the precise arrangement and orientation of collagen fibrils, made of mostly Type I and V collagen fibrils and proteoglycans (PGs). PGs are essential for correct collagen fibrillogenesis and maintaining corneal homeostas
Externí odkaz:
https://doaj.org/article/a09bab986b0741d58aeb1be8c716bd00
Autor:
Sudhir Verma, Isabel Y. Moreno, Morgan E. Trapp, Luis Ramirez, Tarsis F. Gesteira, Vivien J. Coulson-Thomas
Publikováno v:
Differentiation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b58dc2582cea8b16657e1513a64d6ce9
https://doi.org/10.1016/j.diff.2023.04.005
https://doi.org/10.1016/j.diff.2023.04.005
Autor:
Xiao Lin, Taye Mekonnen, Sudhir Verma, Christian Zevallos-Delgado, Manmohan Singh, Salavat R. Aglyamov, Tarsis F. Gesteira, Kirill V. Larin, Vivien J. Coulson-Thomas
Publikováno v:
Investigative ophthalmologyvisual science. 63(13)
Hyaluronan (HA) is a major constituent of the extracellular matrix (ECM) that has high viscosity and is essential for maintaining tissue hydration. In the cornea, HA is enriched in the limbal region and is a key component of the limbal epithelial ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367f1613a58a0e7054672f35ec94bfdf
https://pubmed.ncbi.nlm.nih.gov/36478198
https://pubmed.ncbi.nlm.nih.gov/36478198