Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Tarsila G. Castro"'
Publikováno v:
Journal of Natural Fibers, Vol 20, Iss 1 (2023)
Commercial hair perming uses strong reducing agents and harms hair fiber’s quality even human health. In this study, tyrosine is adopted as a cross-linking agent between thiols and/or amines as the shape-changing of hair involves the breakage of di
Externí odkaz:
https://doaj.org/article/3970cee096034f94aed542c84b95a8dd
Autor:
Tarsila G. Castro, Manuel Melle-Franco, Cristina E. A. Sousa, Artur Cavaco-Paulo, João C. Marcos
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 981 (2023)
This review provides a fresh overview of non-canonical amino acids and their applications in the design of peptidomimetics. Non-canonical amino acids appear widely distributed in nature and are known to enhance the stability of specific secondary str
Externí odkaz:
https://doaj.org/article/332b1706db364d5c98cacec22c789940
Publikováno v:
Polymers, Vol 15, Iss 7, p 1703 (2023)
The phosphatidylinositol-3 kinase (PI3K) pathway is one of the most frequently activated pathogenic signalling cascades in a wide variety of cancers. In the last 15 years, there has been an increase in the search for selective inhibitors of the four
Externí odkaz:
https://doaj.org/article/69ae1ed0b63a4aba8e2d6e82f5876aa9
Publikováno v:
Polymers, Vol 15, Iss 4, p 796 (2023)
The world of cosmetics is an always-evolving field with constant updates on its formulation components. The current reality asks for an ever-increasing need for natural and sustainable replacements for synthetic compounds in all fields of modern cons
Externí odkaz:
https://doaj.org/article/03f6f69ff0b84b43b6e29e261b02f116
Autor:
Carlos B. P. Oliveira, Renato B. Pereira, David M. Pereira, Loic Hilliou, Tarsila G. Castro, José A. Martins, Peter J. Jervis, Paula M. T. Ferreira
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11811 (2022)
Employing amino acids and peptides as molecular building blocks provides unique opportunities for generating supramolecular hydrogels, owing to their inherent biological origin, bioactivity, biocompatibility, and biodegradability. However, they can s
Externí odkaz:
https://doaj.org/article/69557f2214c44dcc9d5210129b9fdc1e
Publikováno v:
Biomolecules, Vol 11, Iss 2, p 145 (2021)
The binding of known odorant molecules to the human odorant-binding protein (hOBP) was evaluated in silico. Docking experiments elucidate the preferable binding site and binding affinity of odorant molecules to hOBP. The physicochemical properties mo
Externí odkaz:
https://doaj.org/article/6b551048337f46cf919d073701f449d9
Publikováno v:
Biomolecules, Vol 9, Iss 3, p 116 (2019)
Tau is a microtubule-associated protein that promotes microtubule assembly and stability. This protein is implicated in several neurodegenerative diseases, including Alzheimer’s. To date, the three-dimensional (3D) structure of tau has not been ful
Externí odkaz:
https://doaj.org/article/648c557af99b49dba28f2b021dbff0cf
Autor:
David S. Freitas, Diana Rocha, Tarsila G. Castro, Jennifer Noro, Vânia I. B. Castro, Marta A. Teixeira, Rui L. Reis, Artur Cavaco-Paulo, Carla Silva
Publikováno v:
ACS Sustainable Chemistry & Engineering. 10:7974-7989
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd729f94cc086bf0b0e2736a24f79d9f
https://doi.org/10.1021/acssuschemeng.2c01422
https://doi.org/10.1021/acssuschemeng.2c01422
Autor:
Tarsila G. Castro, Tiago Ferreira, Teresa Matamá, Florentina-Daniela Munteanu, Artur Cavaco-Paulo
The microtubule-associated protein Tau has its normal function impaired when undergoing post-translational modifications. In this work, molecular modelling techniques were used to infer the effects of acetylation and phosphorylation in Tau's overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fbb5a27eda205f55573b0df1893975
https://hdl.handle.net/1822/80674
https://hdl.handle.net/1822/80674
The search for Golgi α-mannosidase II (GMII) potent and specific inhibitors has been a focus of many studies for the past three decades since this enzyme is a key target for cancer treatment. α-Mannosidases, such as those from Drosophila melanogast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb970b5fc3e9c9c876b4d94a2bee5a20