Intein Inhibitors as Novel Antimicrobials: Protein Splicing in Human Pathogens, Screening Methods, and Off-Target Considerations.

Autor: Wall DA; Department of Chemistry, College of the Holy Cross, Worcester, MA, United States., Tarrant SP; Department of Chemistry, College of the Holy Cross, Worcester, MA, United States., Wang C; Department of Biological Sciences, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States.; Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, United States., Mills KV; Department of Chemistry, College of the Holy Cross, Worcester, MA, United States., Lennon CW; Department of Biological Sciences, Murray State University, Murray, KY, United States.

Publikováno v: Frontiers in molecular biosciences [Front Mol Biosci] 2021 Oct 07; Vol. 8, pp. 752824. Date of Electronic Publication: 2021 Oct 07 (Print Publication: 2021).