Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Taro Shiraishi"'
Autor:
Genki Hibi, Taro Shiraishi, Tatsuki Umemura, Kenji Nemoto, Yusuke Ogura, Makoto Nishiyama, Tomohisa Kuzuyama
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Type II polyketide synthases (PKSs) normally synthesize polycyclic aromatic compounds in nature, and the potential to elaborate further diverse skeletons was recently revealed by the discovery of a polyene subgroup. Here, we show a type II P
Externí odkaz:
https://doaj.org/article/6be799ad3b484de7aee7bf12274d622b
Autor:
Satomi Sumikawa, Yoshihiro Yakushijin, Kenjiro Aogi, Takuya Yano, Hiroki, Hashimoto, Chiyuki Tsukui, Tadashi Noguchi, Taro Shiraishi, Yasuhiro Horikawa, Yasuo Yasuoka, Akihiro Tanaka, Noriaki Hidaka, Mamoru Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Occupational exposure of anticancer agents during their preparation has been recognized as a serious hazard. Closed system drug transfer devices (CSTDs) enable “safe” preparation of agents for medical personnel and ensure a safe hospital
Externí odkaz:
https://doaj.org/article/1c5d7bf0257448a49e665910b585b170
Autor:
Yuxun Zhu, Taro Shiraishi, Jianwen Lin, Keito Inaba, Atsuro Ito, Yusuke Ogura, Makoto Nishiyama, Tomohisa Kuzuyama
Publikováno v:
Journal of the American Chemical Society. 144(37)
Phosphonates often exhibit biological activities by mimicking the phosphates and carboxylates of biological molecules. The phosphonate phosphonothrixin (PTX), produced by the soil-dwelling bacterium
Autor:
Sumire Kurosawa, Kenichi Matsuda, Fumihito Hasebe, Makoto Nishiyama, Tomohisa Kuzuyama, Taro Shiraishi, Kazuo Shin-ya
Publikováno v:
Organic & Biomolecular Chemistry. 18:5137-5144
The 1-azabicyclo[3.1.0]hexane ring is a key moiety in natural products for biological activities against bacteria, fungi, and tumor through DNA alkylation. Ficellomycin is a dipeptide that consists of l-valine and a non-proteinogenic amino acid with
Autor:
Xiaofei Shao, Chang Zheng, Peng Xu, Taro Shiraishi, Tomohisa Kuzuyama, Antonio Molinaro, Alba Silipo, Biao Yu
A collective total synthesis of eight diastereoisomers associated with NMR analysis leads to a full stereochemistry assignment of the structurally unique nucleoside antibiotic A-94964, which features an octuronic acid uridine core decorated with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac0708d248ae0dca9b1a47b2583cea6
http://hdl.handle.net/11588/880157
http://hdl.handle.net/11588/880157
Publikováno v:
The Journal of antibiotics. 74(11)
The nucleoside antibiotic angustmycin, produced by some Streptomyces strains, is composed of adenine and C6 sugar and shows antibiotic and antitumor activities. In this study, we propose a biosynthetic pathway for angustmycin using a heterologous exp
Autor:
Taro Shiraishi, Tomohisa Kuzuyama
Publikováno v:
The Journal of Antibiotics. 72:913-923
Nucleoside antibiotics are a diverse class of natural products with promising biomedical activities. These compounds contain a saccharide core and a nucleobase. Despite the large number of nucleoside antibiotics that have been reported, biosynthetic
Autor:
Yasushi Ogasawara, Taro Shiraishi, Priscilla H. Liem, Hideo Ikeuchi, Yu-Hsuan Lee, Makoto Nishiyama, Geng-Min Lin, Tomohisa Kuzuyama, Yujie Geng, Tianlu Ma, Anthony J. Romo, Kazuo Shin-ya, Hung-wen Liu
Publikováno v:
Journal of the American Chemical Society. 141:14152-14159
Peptidyl nucleoside antibiotics (PNAs) are a diverse class of natural products with promising biomedical activities. These compounds have tripartite structures composed of a core saccharide, a nucleobase, and one or more amino acids. In particular, a
Publikováno v:
Organic & Biomolecular Chemistry. 17:461-466
The natural product A-94964 is a uridine-derived nucleoside antibiotic isolated from Streptomyces sp. SANK 60404. In this study, we propose a biosynthetic pathway for A-94964 using gene deletion experiments coupled with in silico analysis of the bios
Autor:
Yasuo Yasuoka, Tadashi Noguchi, Taro Shiraishi, Akihiro Tanaka, Mamoru Tanaka, Hiroki Hashimoto, Yoshihiro Yakushijin, Takuya Yano, Yasuhiro Horikawa, Chiyuki Tsukui, Kenjiro Aogi, Satomi Sumikawa, Noriaki Hidaka
Occupational exposure of anticancer agents during their preparation has been recognized as a serious hazard. Closed system drug transfer devices (CSTDs) enable “safe” preparation of agents for medical personnel and ensure a safe hospital environm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbe2b7f56c743b8fa493509a3e046dfa
https://doi.org/10.21203/rs.3.rs-418319/v1
https://doi.org/10.21203/rs.3.rs-418319/v1