Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Taro Kakuzaki"'
Autor:
Taro Kakuzaki, Hikaru Koga, Shuuki Takizawa, Shoichi Metsugi, Hirotake Shiraiwa, Zenjiro Sampei, Kenji Yoshida, Hiroyuki Tsunoda, Reiji Teramoto
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTAntibodies are one of the predominant treatment modalities for various diseases. To improve the characteristics of a lead antibody, such as antigen-binding affinity and stability, we conducted comprehensive substitutions and exhaustively expl
Externí odkaz:
https://doaj.org/article/464d1ce6486045f391b77c27fa515809
Autor:
Koichiro Saka, Taro Kakuzaki, Shoichi Metsugi, Daiki Kashiwagi, Kenji Yoshida, Manabu Wada, Hiroyuki Tsunoda, Reiji Teramoto
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Molecular evolution is an important step in the development of therapeutic antibodies. However, the current method of affinity maturation is overly costly and labor-intensive because of the repetitive mutation experiments needed to adequatel
Externí odkaz:
https://doaj.org/article/b637d0a8f2934168ad948f2310d11803
Autor:
Shoichi Metsugi, Reiji Teramoto, Hiroyuki Tsunoda, Koichiro Saka, Manabu Wada, Taro Kakuzaki, Daiki Kashiwagi, Kenji Yoshida
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Molecular evolution is an important step in the development of therapeutic antibodies. However, the current method of affinity maturation is overly costly and labor-intensive because of the repetitive mutation experiments needed to adequately explore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876e9eb78c3fa55d17a005c7a539f132
http://europepmc.org/articles/PMC7955064
http://europepmc.org/articles/PMC7955064