Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Taro Amagata"'
Autor:
Ten-Yang Yen, Stephanie R. Gee, Hana Martucci, Walter M. Bray, Trevor Gokey, Scott Campit, A. King Cada, Taro Amagata, Katsuhiko Minoura, Anton B. Guliaev, R. Scott Lokey
Publikováno v:
Journal of Natural Products. 80:684-691
HeLa cell-based cytological profiling (CP) was applied to an extract library of marine sediment-derived actinomycetes to discover new cytotoxic secondary metabolites. Among the hit strains, Streptomyces sp. CP26-58 was selected for further investigat
Publikováno v:
Tetrahedron Letters. 61:151778
Malonic acid monoanilides were obtained in excellent yield from the reaction of anilines with Meldrum’s acid under solvent-free conditions. The malonic acid monoanilide intermediates were then treated with methanesulfonic acid anhydride (MSAA) to p
Autor:
Reiko Tanaka, Yoshihide Usami, Kyoko Nakanishi, Taro Amagata, Katsuhiko Minoura, Atsushi Numata, Takeshi Yamada, Mitsunobu Doi
Publikováno v:
Tetrahedron. 69:4617-4623
Anthcolorins A–F were isolated from a strain of Aspergillus versicolor originally isolated from the sea urchin Anthocidaris crassispana, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and 2D
Autor:
Anton B. Guliaev, Trevor Gokey, Jing Xiao, Taro Amagata, Nicholas Holsopple, Katsuhiko Minoura, Yi-Pei Chen, Allen G. Oliver
Publikováno v:
Journal of Natural Products. 75:2193-2199
A histone deacetylase (HDAC)-based yeast assay employing a URA3 reporter gene was applied as a primary screen to evaluate a marine-derived actinomycete extract library and identify human class III HDAC (SIRT) inhibitors. Based on the bioassay-guided
Autor:
Brandon I. Morinaka, Sarah J. Robinson, Joseph Media, Phillip Crews, Katharine R. Watts, Taro Amagata, Walter M. Bray, Nadine C. Gassner, R. Scott Lokey, Karen Tenney, Frederick A. Valeriote
Publikováno v:
Journal of Natural Products. 74:341-351
The cyclodepsipeptide jasplakinolide (1) (a.k.a. jaspamide), isolated previously from the marine sponge Jaspis splendens, is a unique cytotoxin and molecular probe that operates through stabilization of filamentous actin (F-actin). We have recently d
Publikováno v:
Tetrahedron Letters. 54:5960-5962
A continuous investigation of secondary metabolites produced by the sponge-derived fungus, Gymnascella dankaliensis , has yielded a new polyketide tyrosine derivative, dankastatin C ( 3 ) and the known steroid, demethylincisterol A 3 ( 4 ), which was
Autor:
James H. McKerrow, Phillip Crews, Allen G. Oliver, Karen Tenney, Taro Amagata, Teatulohi Matainaho, Tyler A. Johnson, Koneni V. Sashidhara, Kenny K. H. Ang
Publikováno v:
Organic Letters. 11:1975-1978
A survey of individual specimens of northern Papua New Guinea derived Cacospongia mycofijiensis has yielded novel sesquiterpenes, aignopsanoic acid A (1), methyl aignopsanoate A (2), and isoaignopsanoic acid A (3). The structures and absolute configu
Autor:
Frederick A. Valeriote, Allen G. Oliver, Phillip Crews, Taro Amagata, Tyler A. Johnson, Karen Tenney
Publikováno v:
The Journal of Organic Chemistry. 73:7255-7259
A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431 (1). Its structure including absolute configuration as 8R,9R,10S,13S was established using NMR data, calculated
Publikováno v:
Journal of Natural Products. 71:340-345
Four new metabolites, gymnastatins Q ( 3) and R ( 4) and dankastatins A ( 5) and B ( 6), have been isolated from the mycelial MeOH extract of a fungal strain of Gymnascella dankaliensis separated from a Halichondria sponge. Their stereostructures hav
Autor:
Takao Yamori, Atsushi Numata, Katsuhiko Minoura, Hirofumi Ohishi, Taro Amagata, Takeshi Yamada, Mitsunobu Doi, Makoto Tanaka
Publikováno v:
Journal of Natural Products. 70:1731-1740
The Halichondria sponge-derived fungus, Gymnacella dankaliensis, was cultured in two different media conditions. A modified malt extract medium containing soluble starch instead of glucose resulted in two extremely unusual steroids, dankasterones A (