Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Taro, Okada"'
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The insulin-like growth factor II/mannose 6-phosphate (IGF-II/M6P) receptor is a multifunctional glycoprotein not only play roles in IGF-II degradation and pro-TGFβ activation but binding to and transport M6P-bearing lysosomal enzymes from
Externí odkaz:
https://doaj.org/article/ffdd742922a049158cafb4656a97caee
Autor:
Taro Okada, Susumu Nishida, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Tianyou Wang, Takeshi Ijuin, Taketoshi Kajimoto, Shun-Ichi Nakamura
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103351- (2021)
Summary: The importance of the G-protein βγ subunits in the regulation of cargo transport from the trans-Golgi network (TGN) to the plasma membrane (PM) is well accepted; however, the molecular mechanism underlying the G-protein activation at the T
Externí odkaz:
https://doaj.org/article/75eaec608d4b498a8de513a8224e8905
Autor:
Naoya Tsuboi, MD, Yukihiko Yoshida, MD, Matsumoto Masaya, MD, Takashi Yamamoto, MD, Yutaka Aoyama, MD, Makoto Ishikawa, MD, Yasuhiro Ogura, MD, Hirohiko Suzuki, MD, Kentaro Yamashita, MD, Takashi Muramatsu, MD, Mamoru Nanasato, MD, Haruo Hirayama, MD, Teruo Itoh, MD, Taro Okada, MD, Takumi Yamada, MD, Yoshimasa Murakami, MD, Takahisa Kondo, MD, Yasuya Inden, MD, Toyoaki Murohara, MD, Itsuo Kodama, MD, Junji Toyama, MD
Publikováno v:
Journal of Arrhythmia, Vol 22, Iss 4, Pp 225-233 (2006)
Electrical isolation of the pulmonary veins (PV) has become a curative treatment for patients with atrial fibrillation (AF). Recently, there have been many reports that circumferential PV isolation (CPI) on the atrial side has a better outcome than s
Externí odkaz:
https://doaj.org/article/b1f45bfbda9a40b384d71e103a92cf5f
Autor:
Hiroaki Nagase, Hikaru Kitahara, Takeshi Ninchoji, Yoshinori Araki, Ryojiro Tanaka, Toru Igarashi, Shinya Ishiko, Kazumoto Iijima, Kandai Nozu, Eri Okada, Koji Nagatani, Naoya Morisada, Kumiko Jinnouchi, Nana Sakakibara, Takeshi Ijuin, Shogo Minamikawa, Taro Okada, China Nagano, Toju Tanaka, Mari S Harada, Takeshi Matsuyama, Tomoko Horinouchi, Rini Rossanti, Yasufumi Ohtsuka, Koichi Kamei, Yuya Aoto, Shun-ichi Nakamura, Hiroyuki Awano, Masafumi Oka, Tomohiko Yamamura
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 37(2)
Background Although Lowe syndrome and Dent disease-2 are caused by Oculocerebrorenal syndrome of Lowe (OCRL) mutations, their clinical severities differ substantially and their molecular mechanisms remain unclear. Truncating mutations in OCRL exons 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ad5b6640f41e611604a6ae5e3331c1
https://pubmed.ncbi.nlm.nih.gov/34586410
https://pubmed.ncbi.nlm.nih.gov/34586410
Autor:
Shubi Ambwene, Matovelo, Lifang, Zhang, Nesma Nabil Ibrahim, Mohamed, Taketoshi, Kajimoto, Takeshi, Ijuin, Taro, Okada, Shun-Ichi, Nakamura
Publikováno v:
Kobe J Med Sci
Macropinocytosis is a highly conserved cellular process of endocytosis by which extracellular fluid and nutrients are taken up into cells through large, heterogeneous vesicles known as macropinosomes. Growth factors such as epidermal growth factor (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82454161f3fc2bcfb3cfce5d8ef72ce4
https://pubmed.ncbi.nlm.nih.gov/33431782
https://pubmed.ncbi.nlm.nih.gov/33431782
Publikováno v:
Journal of Insect Biotechnology & Sericology; 2022, Vol. 91 Issue 3, p33-39, 7p
Autor:
Taro Okada, Shaymaa Mohamed Mohamed Badawy, Taketoshi Kajimoto, Shun-ichi Nakamura, Shunsuke Nakamura, Shubi Ambwene Matovelo, Mitsuhiro Hirase, Takeshi Ijuin, Daisuke Yoshida
Publikováno v:
Journal of Biological Chemistry. 293(21):8208-8216
α-Synuclein (α-Syn)-positive intracytoplasmic inclusions, known as Lewy bodies, are thought to be involved in the pathogenesis of Lewy body diseases, such as Parkinson's disease (PD). Although growing evidence suggests that cell-to-cell transmissio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0151cec8b45c7b403228486846401768
https://hdl.handle.net/20.500.14094/90005588
https://hdl.handle.net/20.500.14094/90005588
Autor:
Shubi Ambwene Matovelo, Shun-ichi Nakamura, Nesma Nabil Ibrahim Mohamed, Mitsuhiro Hirase, Daisuke Yoshida, Takeshi Ijuin, Shaymaa Mohamed Mohamed Badawy, Taro Okada, Taketoshi Kajimoto, Shunsuke Nakamura
Publikováno v:
Journal of Biological Chemistry. 293(1):245-253
Exosomes play a critical role in cell-to-cell communication by delivering cargo molecules to recipient cells. However, the mechanism underlying the generation of the exosomal multivesicular endosome (MVE) is one of the mysteries in the field of endos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e813e86dae9b30e7ac16e241e3d0478
https://hdl.handle.net/20.500.14094/90005587
https://hdl.handle.net/20.500.14094/90005587
Autor:
Chise Tateno, Masakazu Kakuni, Masashi Uchida, Eri Sakurada, Yoriko Tajima, Taro Okada, Yutaka Kageyama, Ryoji Hayashi
Publikováno v:
Drug Metabolism and Disposition. 46:11-19
The influence of transporters on the pharmacokinetics of drugs is being increasingly recognized, and DDIs via transporters may be a risk factor for adverse events. Cyclosporine A, a strong OATP inhibitor, has been reported to increase the systemic ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025aae89cb898e8fbaeb97e5540e2ca7
https://doi.org/10.1124/dmd.117.075994
https://doi.org/10.1124/dmd.117.075994
Autor:
Caila A. Pilo, An-Angela N. Van, Taro Okada, Alisha D. Caliman, J. Andrew McCammon, Alexandra C. Newton, Taketoshi Kajimoto, Shun-ichi Nakamura, Irene S. Tobias
Publikováno v:
Science Signaling. 12
Atypical protein kinase C (aPKC) isozymes are unique in the PKC superfamily in that they are not regulated by the lipid second messenger diacylglycerol, which has led to speculation about whether a different second messenger acutely controls their fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc5ac0219d660752291cd448cfba160b
https://doi.org/10.1126/scisignal.aat6662
https://doi.org/10.1126/scisignal.aat6662