Uncovering the inhibitory potentials of Phyllanthus nivosus leaf and its bioactive compounds against Plasmodium lactate dehydrogenase for malaria therapy.

Autor: Johnson TO; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria.; Biotechnology Research Unit, Jaris Computational Biology Center, Jos, Nigeria., Adegboyega AE; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria.; Biotechnology Research Unit, Jaris Computational Biology Center, Jos, Nigeria., Johnson GI; Biotechnology Research Unit, Jaris Computational Biology Center, Jos, Nigeria.; College of Health Sciences, University of Jos, Jos, Nigeria., Umedum NL; Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria., Bamidele OD; Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria., Elekan AO; Department of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Nigeria., Tarkaa CT; Cell Biology and Genetics Unit, Department of Zoology, University of Ibadan, Ibadan, Nigeria., Mahe A; Department of Biochemistry, Federal University, Dutse, Jigawa State, Nigeria., Abdulrahman A; Department of Pharmacognosy and Drug Development, Ahmadu Bello University, Zaria, Nigeria., Adeyemi OE; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria., Okafor D; Department of Biochemistry, Faculty of Basic Medical Sciences, University of Jos, Jos, Nigeria., Yusuf AJ; Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria., Atewolara-Odule OC; Department of Chemical Sciences, Olabisi Onabanjo University, Ago-Iwoye, Nigeria., Ogunmoye AO; Department of Chemical Sciences, Olabisi Onabanjo University, Ago-Iwoye, Nigeria., Ishaya T; Department of Computer Science, University of Jos, Jos, Nigeria.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2023 Nov; Vol. 41 (19), pp. 9787-9796. Date of Electronic Publication: 2022 Nov 21.