Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Tarja Puumala"'
Publikováno v:
Epileptic Disorders. 16:191-195
New antiepileptic drug (AED) options for generalised seizure types have been adopted for use as treatment for Unverricht-Lundborg disease. Whether this has led to improved seizure control or functional outcome in ULD patients remains obscure. We retr
Autor:
Tiina Koskinen, Sirja Ruotsalainen, Jouni Sirviö, Pekka T. Männistö, Esa Koivisto, Raimo Lappalainen, Tarja Puumala
Publikováno v:
Neuropharmacology. 39:471-481
The present experiments investigated the effects of agents acting at serotonin (5-HT)-2 receptors on the performance of rats in a choice serial reaction time (5-CSRT) task in order to examine the role of 5-HT2 receptors in the modulation of attention
Autor:
Tarja Puumala, Jouni Sirviö, Kaisa Narinen, Paavo Riekkinen, Antti Haapalinna, Susanna Greijus
Publikováno v:
European Neuropsychopharmacology. 8:17-26
The present experiments were designed to examine the effects of alpha-1 adrenergic stimulation and inhibition on memory encoding and to investigate whether the alpha-1 adrenergic and muscarinic cholinergic systems interact in the regulation of spatia
Autor:
Sirja Ruotsalainen, Paavo Riekkinen, Pekka Jäkälä, Jouni Sirviö, Tarja Puumala, Ewen MacDonald
Publikováno v:
European Neuropsychopharmacology. 7:99-108
The effects of three different serotonin (5-HT) receptor antagonists (ketanserin, methysegide, methiothepin) in the modulation of attention, working memory and behavioural activity were investigated in this study by assessing the performance of rats
Autor:
Ewen MacDonald, Paavo Riekkinen, Jouni Sirviö, Sirja Ruotsalainen, Tarja Puumala, Riitta Miettinen
Publikováno v:
Psychopharmacology. 130:303-312
The role of serotonin (5-HT) and its interaction with the muscarinic or nicotinic receptor-mediated mechanisms in the modulation of working memory and motor activity was investigated by assessing the effects of 5-HT lesion and cholinergic receptor bl
Autor:
Tarja Puumala, Paavo Riekkinen, Pekka Jäkälä, Jouni Sirviö, Minna Riekkinen, Erkki Björk, Antti Haapalinna, Markus Björklund, Sirja Ruotsalainen
Publikováno v:
Brain Research Bulletin. 43:163-171
A five-choice serial reaction time (5-CSRT) task was used to assess attention in rats. In this behavioral paradigm, the rats are required to spatially discriminate a short visual stimulus that will occur randomly in one of five locations while mainta
Autor:
Tarja Puumala, Jouni Sirviö
Publikováno v:
Journal of Psychopharmacology. 11:45-51
The present study investigated the role of α1 adrenergic receptors in the modulation of working memory and behavioural activity by assessing the effects of α1 adrenergic receptor stimulation or blockade on the performance of rats in a delayed non-m
Publikováno v:
Pharmacology Biochemistry and Behavior. 55:107-115
The present experiments were designed to investigate whether the alpha-1 adrenergic and muscarinic cholinergic systems interact in the regulation of spatial navigation behavior in the Morris water maze test and passive avoidance performance. Pretrain
Publikováno v:
Neurobiology of learning and memory. 66(2)
Childhood hyperactivity (attention deficit hyperactivity disorder, ADHD) is a common behavior disorder among grade-school children. The characteristic symptoms are attentional problems and hyperkinesia. A number of animal models for ADHD syndrome hav
Autor:
Hakkarainen, Raimo Lappalainen, Tarja Puumala, Antti Haapalinna, Sirja Ruotsalainen, Minna Niittykoski, Jouni Sirviö
Publikováno v:
Behavioural Pharmacology. 8:465
The present study investigated whether an alpha 2-adrenoceptor antagonist (atipamezole) can influence hyperactivity induced by the systemic administration of scopolamine. In the water maze (WM) task, scopolamine (scop) 0.25 mg/kg treatment significan