Cardiovascular magnetic resonance measures of aortic stiffness in asymptomatic patients with type 2 diabetes: association with glycaemic control and clinical outcomes

Autor: Peter P. Swoboda, Bara Erhayiem, Rachel Kan, Adam K. McDiarmid, Pankaj Garg, Tarique A. Musa, Laura E. Dobson, Klaus K. Witte, Mark T. Kearney, Julian H. Barth, Ramzi Ajjan, John P. Greenwood, Sven Plein

Publikováno v: Cardiovascular Diabetology, Vol 17, Iss 1, Pp 1-9 (2018)

Abstract Background We aimed to investigate in patients with type 2 diabetes whether aortic stiffness is: (i) associated with glycaemic control, (ii) associated with adverse outcomes and (iii) can be reversed on treatment with RAAS inhibition. Method

Externí odkaz: https://doaj.org/article/f0e638cc9d5f4c4bb43edfcf7259f0f5

Diabetes Mellitus, Microalbuminuria, and Subclinical Cardiac Disease: Identification and Monitoring of Individuals at Risk of Heart Failure

Autor: Peter P. Swoboda, Adam K. McDiarmid, Bara Erhayiem, David P. Ripley, Laura E. Dobson, Pankaj Garg, Tarique A. Musa, Klaus K. Witte, Mark T. Kearney, Julian H. Barth, Ramzi Ajjan, John P. Greenwood, Sven Plein

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 7 (2017)

BackgroundPatients with type 2 diabetes mellitus and elevated urinary albumin:creatinine ratio (ACR) have increased risk of heart failure. We hypothesized this was because of cardiac tissue changes rather than silent coronary artery disease. Methods

Externí odkaz: https://doaj.org/article/20337c7f2fb64146850b5d12799a9f43

Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis

Autor: Gabriella Captur, Tobias Rheude, Taehoon Ko, Trisha Singh, Marzia Rigolli, João L. Cavalcante, Marie-Annick Clavel, Philippe Pibarot, Doyeon Hwang, David E. Newby, Marc R. Dweck, Shruti S Joshi, Sung-Ji Park, Rong Bing, Vanessa M Ferreira, Bernhard Gerber, Jeanette Schulz-Menger, Soongu Kwak, Sahmin Lee, Anvesha Singh, Heesun Lee, Tarique A Musa, Thomas A. Treibel, Gerry P McCann, Whal Lee, Martin Hadamitzky, Lionel Tastet, Calvin W. L. Chin, Miho Fukui, Michelle C. Williams, Russell J. Everett, Seokhun Yang, Erik B. Schelbert, Laura E Dobson, James C. Moon, Yong Jin Kim, John P Greenwood, Seung Pyo Lee, Stephanie Wiesemann, Saul G. Myerson

Publikováno v: Journal of the American College of Cardiology, Vol. 78, no.6, p. 545-558 (2021)
Kwak, S, Everett, R J, Treibel, T A, Yang, S, Hwang, D, Ko, T, Williams, M C, Bing, R, Singh, T, Joshi, S, Lee, H, Lee, W, Kim, Y-J, Chin, C W L, Fukui, M, Musa, T A, Rigolli, M, Singh, A, Tastet, L, Dobson, L E, Wiesemann, S, Ferreira, V M, Captur, G, Lee, S, Schulz-Menger, J, Schelbert, E B, Clavel, M-A, Park, S-J, Rheude, T, Hadamitzky, M, Gerber, B L, Newby, D E, Myerson, S G, Pibarot, P, Cavalcante, J L, McCann, G P, Greenwood, J P, Moon, J C, Dweck, M R & Lee, S-P 2021, ' Markers of Myocardial Damage Predict Mortality in Patients with Aortic Stenosis ', Journal of the American College of Cardiology . https://doi.org/10.1016/j.jacc.2021.05.047

Background Cardiovascular magnetic resonance (CMR) is increasingly used for risk stratification in aortic stenosis (AS). However, the relative prognostic power of CMR markers and their respective thresholds remains undefined. Objectives Using machine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa819de0988c4c6be3014303ae60af10
https://hdl.handle.net/2078.1/249928

Extracellular myocardial volume in patients with aortic stenosis

Autor: Laura E Dobson, Marzia Rigolli, Lionel Tastet, Marie-Annick Clavel, Gabriella Captur, John P Greenwood, David E. Newby, Russell J. Everett, Gerry P McCann, Stefan K. Piechnik, Miho Fukui, João L. Cavalcante, Phillipe Pibarot, Thomas A. Treibel, Vanessa M Ferreira, Heesun Lee, Sahmin Lee, Petra Bijsterveld, Anvesha Singh, Erik B. Schelbert, Marc R. Dweck, Sang Yong Om, Jeanette Schulz-Menger, Tarique A Musa, Calvin W. L. Chin, James C. Moon, Stephanie Wiesemann, Seung Pyo Lee, Saul G. Myerson

Publikováno v: Everett, R J, Treibel, T A, Fukui, M, Lee, H, Rigolli, M, Singh, A, Bijsterveld, P, Tastet, L, Musa, T A, Dobson, L, Chin, C, Captur, G, Yong Om, S, Wiesemann, S, Ferreira, V M, Piechnik, S K, Schulz-Menger, J, Schelbert, E B, Clavel, M-A, Newby, D E, Myerson, S G, Pibarot, P, Lee, S, Cavalcante, J L, Lee, S-P, McCann, G P, Greenwood, J P, Moon, J C & Dweck, M R 2020, ' Extracellular Myocardial Volume in Patients With Aortic Stenosis ', Journal of the American College of Cardiology, vol. 75, no. 3, pp. 304-316 . https://doi.org/10.1016/j.jacc.2019.11.032

Background:Myocardial fibrosis is a key mechanism of left ventricular decompensation in aortic stenosis and can be quantified using cardiovascular magnetic resonance (CMR) measures such as extracellular volume fraction (ECV%). Outcomes following aort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::746a58a12e77c2f408da6f54d77cf2fc
https://doi.org/10.1016/j.jacc.2019.11.032

CMR quantitation of change in mitral regurgitation following transcatheter aortic valve replacement (TAVR): impact on left ventricular reverse remodeling and outcome

Autor: Graham J. Fent, Tarique A Musa, James R. J. Foley, Laura E Dobson, Louise A. E. Brown, Sven Plein, John P Greenwood, Pankaj Garg, Pei G. Chew, Akhlaque Uddin, Sebastian Onciul, Timothy A. Fairbairn, Daniel J. Blackman, Peter P Swoboda

Publikováno v: The International Journal of Cardiovascular Imaging

Current echocardiographic data reporting the impact of concomitant mitral regurgitation (MR) on outcome in patients who undergo transcatheter aortic valve replacement (TAVR) are conflicting. Using cardiovascular magnetic resonance (CMR) imaging, this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238efbe2241607c24e6672e4697055e4
http://europepmc.org/articles/PMC6373302