Výsledky vyhledávání - "Tariq M, Haqqi"

Akademický článek

Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1β Stimulated Human Chondrocytes

Autor: Mohammad Y. Ansari, Nashrah Ahmad, Tariq M. Haqqi

Publikováno v: Cellular Physiology and Biochemistry, Vol 49, Iss 3, Pp 932-946 (2018)

Background/Aims: Butein (2’,3,4,4’-Tetrahydroxychalcone), a polyphenol produced by several plants including Butea monoserpma, has been reported to exert potent anti-inflammatory activity but the mechanism remains unknown. In the present work we i

Externí odkaz: https://doaj.org/article/dd070502c31848588f7043b5193b17f5

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Akademický článek

Dataset of effect of Wogonin, a natural flavonoid, on the viability and activation of NF-κB and MAPKs in IL-1β-stimulated human OA chondrocytes

Autor: Nazir M. Khan, Abdul Haseeb, Mohammad Y. Ansari, Pratap Devarapalli, Sara Haynie, Tariq M. Haqqi

Publikováno v: Data in Brief, Vol 12, Iss C, Pp 150-155 (2017)

This article contains data related to the article “Wogonin, a plant derived small molecule exerts potent anti-inflammatory and chondroprotective effects through activation of ROS/ERK/Nrf2 signaling pathways in human Osteoarthritis chondrocytes” (

Externí odkaz: https://doaj.org/article/31d3b29ce0fe45fd934b15844fc41c96

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tRNA-derived fragments (tRFs) regulate post-transcriptional gene expression via AGO-dependent mechanism in IL-1β stimulated chondrocytes

Autor: Jonathan A Green, Tariq M. Haqqi, Hope C. Ball, Mohammad Y. Ansari

Publikováno v: Osteoarthritis Cartilage

Summary Objectives Recent studies have shown that tRNA-derived RNA fragments (tRFs) are novel regulators of post-transcriptional gene expression. However, the expression profiles and their role in post-transcriptional gene regulation in chondrocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c925cafeb2acf499ca64b5bd6a99c4
https://doi.org/10.1016/j.joca.2020.04.014

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ERK1/2-Mediated Activation of DRP1 Regulates Mitochondrial Dynamics and Apoptosis in Chondrocytes

Autor: Mohammad Y. Ansari, Tariq M. Haqqi, Kimberly Novak

Publikováno v: Osteoarthritis Cartilage

To determine the Dynamin-related protein 1 (DRP1) regulation of mitochondrial fission in chondrocytes under pathological conditions, an area which is underexplored in osteoarthritis pathogenesis.DRP1 protein expression was determined by immunohistoch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc18fb70a37837381bc55a7a51a1440b
https://europepmc.org/articles/PMC8792336/

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Assessing Chondrocyte Status by Immunofluorescence-Mediated Localization of Parkin Relative to Mitochondria

Autor: Tariq M. Haqqi, Mohammad Y. Ansari

Publikováno v: Methods in Molecular Biology ISBN: 9781071611180

Immunofluorescence staining is a widely used and powerful tool for the visualization and colocalization of two or more proteins and/or cellular organelles. For colocalization studies in fixed cells, one target protein/organelle is immunostained and v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22f003a0188d6c45a4cf997551b365a3
https://doi.org/10.1007/978-1-0716-1119-7_15

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Assessing Chondrocyte Status by Immunofluorescence-Mediated Localization of Parkin Relative to Mitochondria

Autor: Mohammad Y, Ansari, Tariq M, Haqqi

Publikováno v: Methods in molecular biology (Clifton, N.J.). 2245

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ec69cb09d4600d1cb9588cf45f7879e
https://pubmed.ncbi.nlm.nih.gov/33315205

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Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols

Autor: Nashrah Ahmad, Tariq M. Haqqi, Mohammad Y. Ansari

Publikováno v: Biomedicine & Pharmacotherapy, Vol 129, Iss, Pp 110452-(2020)
Biomed Pharmacother

Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible structural and functional changes in the joint and is a major cause of disability and reduced life expectancy in ageing population. Despite the high prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd6752092562632aeaf96593b0543dc
http://www.sciencedirect.com/science/article/pii/S0753332220306454

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Small Non-Coding RNAome of Ageing Chondrocytes

Autor: Mandy J. Peffers, Xuan Liu, Philip Dyer, Yalda Ashraf Kharaz, Jonathan A Green, Tariq M. Haqqi, Yongxiang Fang, Panagiotis Balaskas, Tim J. M. Welting

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 5675, p 5675 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, 21(16):5675. Multidisciplinary Digital Publishing Institute (MDPI)

BackgroundAgeing is one of the leading risk factors predisposing cartilage to musculoskeletal diseases, including osteoarthritis. Cumulative evidence suggests that small non-coding RNAs play a role in cartilage-related pathological changes. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57313df151adf2552a365d5330be2b2d
https://www.mdpi.com/1422-0067/21/16/5675

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Imperatorin suppresses IL-1β-induced iNOS expression via inhibiting ERK-MAPK/AP1 signaling in primary human OA chondrocytes

Autor: Mohammad Y. Ansari, Nashrah Ahmad, Shabana Bano, Tariq M. Haqqi

Publikováno v: Int Immunopharmacol

Joint inflammation is a key player in the pathogenesis of osteoarthritis (OA). Imperatorin, a plant-derived small molecule has been reported to have anti-inflammatory properties; however, its effect on chondrocytes is not known. Here, we investigated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e5a1637445e0fd65bcd3ed28d8bbf2
https://europepmc.org/articles/PMC8418334/

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