Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Tariq A. Akhtar"'
Autor:
Mai N. Nguyen, Dibyendu Chakraborty, Sriganesh Ramachandra Rao, Agnieszka Onysk, Mariusz Radkiewicz, Liliana Surmacz, Ewa Swiezewska, Eric Soubeyrand, Tariq A. Akhtar, Timothy W. Kraft, David M. Sherry, Steven J. Fliesler, Steven J. Pittler
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-10 (2023)
Abstract Retinitis pigmentosa (RP) defines a group of hereditary progressive rod-cone degenerations that exhibit a common phenotype caused by variants in over 70 genes. While most variants in the dehydrodolichyl diphosphate synthase (DHDDS) gene resu
Externí odkaz:
https://doaj.org/article/fee4e4b88da74e74bbf913af60ede5b9
Autor:
Jennifer Holborn, Alicyia Walczyk-Mooradally, Colby Perrin, Begüm Alural, Cara Aitchison, Adina Borenstein, Nina Jones, Jibran Y. Khokhar, Tariq A. Akhtar, Jasmin Lalonde
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 1, Pp 100410- (2023)
Cannflavins A and B are flavonoids that accumulate in the Cannabis sativa plant. These specialized metabolites are uniquely prenylated and highly lipophilic, which may permit their interaction with membrane-bound enzymes and receptors. Although previ
Externí odkaz:
https://doaj.org/article/d89a6be415f545b79923195a134f6468
Autor:
Shoshana Buckhalter, Eric Soubeyrand, Sarah A.E. Ferrone, Duncan J. Rasmussen, Joshua D. Manduca, M. Sameer Al-Abdul-Wahid, Jude A. Frie, Jibran Y. Khokhar, Tariq A. Akhtar, Melissa L. Perreault
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mitragyna speciosa (“kratom”), employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America. Here, the dose-dependent effects of a purified alkaloid kratom extract on neuronal oscillator
Externí odkaz:
https://doaj.org/article/2d61d560aee74f479a787e91522443f3
Autor:
Jerry Vockley, Kristin J Hope, Kevin A Rea, Tariq A. Akhtar, Aaron D. Schimmer, Al-Walid Mohsen, Nawaz Ahmed, Paul A. Spagnuolo, Angelo D'Alessandro, Richard W. Smith, Matthew Tcheng, David A. Hess, Eric Bohrnsen, Mark D. Minden, Preethi Jayanth, Alessia Roma
Publikováno v:
Blood
Paediatrics Publications
Paediatrics Publications
Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for survival. To exploit this altered met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443da9fa36eecb0015e1eae59dab6e2e
https://doi.org/10.1182/blood.2020008551
https://doi.org/10.1182/blood.2020008551
Autor:
Tariq A Akhtar, Kevin A Rea, George A. O'Doherty, Richard W. Smith, Vitor L S Cunha, Xiaofan Liu, Angelo D'Alessandro, Paul A. Spagnuolo, Nawaz Ahmed, Todd L. Lowary, Mark D. Minden, Jerry Vockley, Matthew Tcheng
Publikováno v:
Food Funct
Avocado consumption is associated with numerous health benefits. Avocadyne is a terminally unsaturated, 17-carbon long acetogenin found almost exclusively within avocados with noted anti-leukemia and anti-viral properties. In this study, specific str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea98e502e28ac094460f5114aca5825
https://doi.org/10.1039/d1fo00693b
https://doi.org/10.1039/d1fo00693b
Autor:
Hoang V. Tang, David L. Berryman, Jorrel Mendoza, Jessica P. Yactayo‐Chang, Qin‐Bao Li, Shawn A. Christensen, Charles T. Hunter, Norman Best, Eric Soubeyrand, Tariq A. Akhtar, Gilles J. Basset, Anna K. Block
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 112(1)
Zea mays (maize) makes phytoalexins such as sesquiterpenoid zealexins, to combat invading pathogens. Zealexins are produced from farnesyl diphosphate in microgram per gram fresh weight quantities. As farnesyl diphosphate is also a precursor for many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e5a8ffe69aee348dc08b3d7c097c9a
https://pubmed.ncbi.nlm.nih.gov/35960639
https://pubmed.ncbi.nlm.nih.gov/35960639
Publikováno v:
Planta
Main conclusion A stable isotope-assisted mass spectrometry-based platform was utilized to demonstrate that the plant hormone, salicylic acid, is catabolized to catechol, a widespread secondary plant compound. Abstract The phytohormone salicylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d09d43a6566ded240ffecc15ddb47e
http://europepmc.org/articles/PMC7280317
http://europepmc.org/articles/PMC7280317
Autor:
Tariq A. Akhtar, Kristen Van Gelder, Jeremy Easlick, Jason A. McAlister, Lilia K.A. Virta, Nicholas Prudhomme, Jennifer Geddes-McAlister
Publikováno v:
Plant science : an international journal of experimental plant biology. 303
Dolichol is an essential polyisoprenoid within the endoplasmic reticulum of all eukaryotes. It serves as a membrane bound anchor onto which N-glycans are assembled prior to being transferred to nascent polypeptides, many of which enter the secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d19536609c4641f792ba22b996795aff
https://pubmed.ncbi.nlm.nih.gov/33487357
https://pubmed.ncbi.nlm.nih.gov/33487357
Autor:
Melissa L. Perreault, Rachel-Karson Thériault, Joshua D. Manduca, Jibran Y. Khokhar, Tariq A. Akhtar, Colin R Blight
Publikováno v:
Journal of psychopharmacology (Oxford, England). 34(7)
Background:Mitragynine is the major alkaloid of Mitragyna speciosa (kratom) with potential as a therapeutic in pain management and in depression. There has been debate over the potential side effects of the drug including addiction risk and cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c059d722f2c54c54f5d8e0f9ced5e919
https://pubmed.ncbi.nlm.nih.gov/32248751
https://pubmed.ncbi.nlm.nih.gov/32248751
Autor:
Katarzyna Gawarecka, Kevin A Rea, Witold Danikiewicz, Hanna Siekierska, Lilia K.A. Virta, Liliana Surmacz, Maritza Vatta, Daniel Buszewicz, Ewa Swiezewska, Kristen Van Gelder, Magdalena Kania, Tariq A. Akhtar, Przemyslaw Surowiecki, Jacek Wójcik
Publikováno v:
The Plant Cell. 29:1709-1725
Plants accumulate a family of hydrophobic polymers known as polyprenols, yet how they are synthesized, where they reside in the cell, and what role they serve is largely unknown. Using Arabidopsis thaliana as a model, we present evidence for the invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9aba7752fbeec70f0d289f80815cf6e
https://doi.org/10.1105/tpc.16.00796
https://doi.org/10.1105/tpc.16.00796