Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Tariq A, Akhtar"'
Autor:
Mai N. Nguyen, Dibyendu Chakraborty, Sriganesh Ramachandra Rao, Agnieszka Onysk, Mariusz Radkiewicz, Liliana Surmacz, Ewa Swiezewska, Eric Soubeyrand, Tariq A. Akhtar, Timothy W. Kraft, David M. Sherry, Steven J. Fliesler, Steven J. Pittler
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-10 (2023)
Abstract Retinitis pigmentosa (RP) defines a group of hereditary progressive rod-cone degenerations that exhibit a common phenotype caused by variants in over 70 genes. While most variants in the dehydrodolichyl diphosphate synthase (DHDDS) gene resu
Externí odkaz:
https://doaj.org/article/fee4e4b88da74e74bbf913af60ede5b9
Autor:
Jennifer Holborn, Alicyia Walczyk-Mooradally, Colby Perrin, Begüm Alural, Cara Aitchison, Adina Borenstein, Nina Jones, Jibran Y. Khokhar, Tariq A. Akhtar, Jasmin Lalonde
Publikováno v:
Phytomedicine Plus, Vol 3, Iss 1, Pp 100410- (2023)
Cannflavins A and B are flavonoids that accumulate in the Cannabis sativa plant. These specialized metabolites are uniquely prenylated and highly lipophilic, which may permit their interaction with membrane-bound enzymes and receptors. Although previ
Externí odkaz:
https://doaj.org/article/d89a6be415f545b79923195a134f6468
Autor:
Shoshana Buckhalter, Eric Soubeyrand, Sarah A.E. Ferrone, Duncan J. Rasmussen, Joshua D. Manduca, M. Sameer Al-Abdul-Wahid, Jude A. Frie, Jibran Y. Khokhar, Tariq A. Akhtar, Melissa L. Perreault
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Mitragyna speciosa (“kratom”), employed as a traditional medicine to improve mood and relieve pain, has shown increased use in Europe and North America. Here, the dose-dependent effects of a purified alkaloid kratom extract on neuronal oscillator
Externí odkaz:
https://doaj.org/article/2d61d560aee74f479a787e91522443f3
Autor:
Jerry Vockley, Kristin J Hope, Kevin A Rea, Tariq A. Akhtar, Aaron D. Schimmer, Al-Walid Mohsen, Nawaz Ahmed, Paul A. Spagnuolo, Angelo D'Alessandro, Richard W. Smith, Matthew Tcheng, David A. Hess, Eric Bohrnsen, Mark D. Minden, Preethi Jayanth, Alessia Roma
Publikováno v:
Blood
Paediatrics Publications
Paediatrics Publications
Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for survival. To exploit this altered met
Autor:
Tariq A Akhtar, Kevin A Rea, George A. O'Doherty, Richard W. Smith, Vitor L S Cunha, Xiaofan Liu, Angelo D'Alessandro, Paul A. Spagnuolo, Nawaz Ahmed, Todd L. Lowary, Mark D. Minden, Jerry Vockley, Matthew Tcheng
Publikováno v:
Food Funct
Avocado consumption is associated with numerous health benefits. Avocadyne is a terminally unsaturated, 17-carbon long acetogenin found almost exclusively within avocados with noted anti-leukemia and anti-viral properties. In this study, specific str
Autor:
Hoang V. Tang, David L. Berryman, Jorrel Mendoza, Jessica P. Yactayo‐Chang, Qin‐Bao Li, Shawn A. Christensen, Charles T. Hunter, Norman Best, Eric Soubeyrand, Tariq A. Akhtar, Gilles J. Basset, Anna K. Block
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 112(1)
Zea mays (maize) makes phytoalexins such as sesquiterpenoid zealexins, to combat invading pathogens. Zealexins are produced from farnesyl diphosphate in microgram per gram fresh weight quantities. As farnesyl diphosphate is also a precursor for many
Autor:
Jennifer Holborn, Alicyia Walczyk-Mooradally, Colby Perrin, Begüm Alural, Cara Aitchison, Adina Borenstein, Jibran Y. Khokar, Tariq A. Akhtar, Jasmin Lalonde
Cannflavins A and B are flavonoids that accumulate in the Cannabis sativa plant. These specialized metabolites are uniquely prenylated and highly lipophilic, which, a priori, may permit their interaction with membrane-bound enzymes and receptors. Alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6974283a791d7321b9afb37481b5eca
https://doi.org/10.1101/2022.02.03.478734
https://doi.org/10.1101/2022.02.03.478734
Autor:
Gale G. Bozzo, Cameron Parry, Eric Soubeyrand, Taylor J B Forrester, Jakob Magolan, Matthew S. Kimber, Tariq A. Akhtar, Steven J. Rothstein, M. Sameer Al-Abdul-Wahid, Nicholas G. Jentsch, Colby Perrin, Kelly F. Boddington, Kristen Van Gelder, José A. Casaretto
Publikováno v:
The Plant journal : for cell and molecular biologyREFERENCES. 109(3)
This study focuses on the biosynthesis of a suite of specialized metabolites from Cannabis that are known as the 'bibenzyls'. In planta, bibenzyls accumulate in response to fungal infection and various other biotic stressors; however, it is their wid
Autor:
José A. Casaretto, Kevin A Rea, Jennifer Geddes-McAlister, Arjun Sukumaran, Tariq A. Akhtar, M. Sameer Al-Abdul-Wahid, Steven J. Rothstein
Publikováno v:
Phytochemistry. 164:162-171
In addition to the psychoactive constituents that are typically associated with Cannabis sativa L., there exist numerous other specialized metabolites in this plant that are believed to contribute to its medicinal versatility. This study focused on t
Publikováno v:
Planta
Main conclusion A stable isotope-assisted mass spectrometry-based platform was utilized to demonstrate that the plant hormone, salicylic acid, is catabolized to catechol, a widespread secondary plant compound. Abstract The phytohormone salicylic acid