Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Tariq, Enver"'
Autor:
Sijia Cui, Nicholas McGranahan, Jing Gao, Peng Chen, Wei Jiang, Lingrong Yang, Li Ma, Junfang Liao, Tian Xie, Congying Xie, Tariq Enver, Shixiu Wu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
It is essential to understand heterogeneity and evolution at different omics levels in oesophageal squamous cell carcinoma (ESCC). Here, the authors use multi-omics to analyse heterogeneity and evolution in ESCC patient samples, and characterise the
Externí odkaz:
https://doaj.org/article/ccf44dedac09434bae96f709ca375839
Publikováno v:
HemaSphere, Vol 7, p e4596119 (2023)
Externí odkaz:
https://doaj.org/article/9a700c674c2f4385996f7bbe6a54286d
Autor:
Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The ETV6-RUNX1 chimeric- and native RUNX1-responsive regulomes in paediatric B-acute lymphoblastic leukemia (B-ALL) remain to be characterized. Here, the authors reveal functional antagonism between the two transcription factors predominantly for the
Externí odkaz:
https://doaj.org/article/57a324404a3a49c69acb08a4d571d807
Autor:
Ifat Geron, Angela Maria Savino, Hila Fishman, Noa Tal, John Brown, Virginia A. Turati, Chela James, Jolanda Sarno, Michal Hameiri-Grossman, Yu Nee Lee, Avigail Rein, Hillary Maniriho, Yehudit Birger, Anna Zemlyansky, Inna Muler, Kara L. Davis, Victoria Marcu-Malina, Nicole Mattson, Oren Parnas, Rabea Wagener, Ute Fischer, João T. Barata, Catriona H. M. Jamieson, Markus Müschen, Chun-Wei Chen, Arndt Borkhardt, Ilan Richard Kirsch, Arnon Nagler, Tariq Enver, Shai Izraeli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Activating mutations in Interleukin-7 receptor alpha (IL7Ra) have been reported in B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) but its role in leukaemogenesis is not clear. Here, the authors show that activation of IL7Ra in primary human
Externí odkaz:
https://doaj.org/article/38d90d34ce264d24b343a4ddcc158487
Autor:
Xiaoyan Zhang, Ling Yang, Wanjun Lei, Qiang Hou, Ming Huang, Rongjing Zhou, Tariq Enver, Shixiu Wu
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104125- (2022)
Summary: Background: Tumor heterogeneity of human colorectal cancer (CRC)-initiating cells (CRCICs) in cancer tissues often represents aggressive features of cancer progression. For high-resolution examination of CRCICs, we performed single-cell whol
Externí odkaz:
https://doaj.org/article/08ccd04ab14d463fa1b83348fc7105e2
Autor:
Dylan Stavish, Charlotta Böiers, Christopher Price, Thomas J. R. Frith, Jason Halliwell, Ingrid Saldaña-Guerrero, Jason Wray, John Brown, Jonathon Carr, Chela James, Ivana Barbaric, Peter W. Andrews, Tariq Enver
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Application of pluripotent cells in regenerative medicine requires an understanding of how they exit pluripotency. Here the authors demonstrate support for the idea that pluripotency exit involves pluripotent intermediates that exhibit lineage bias b
Externí odkaz:
https://doaj.org/article/49cf589d5cb741e6a087de76d2e33465
Publikováno v:
International Journal of Infectious Diseases, Vol 99, Iss , Pp 381-385 (2020)
Background: The reasons why some patients with COVID-19 develop pneumonia and others do not are unclear. To better understand this, we used multiparameter flow cytometry to profile circulating leukocytes from non-immunocompromised adult patients with
Externí odkaz:
https://doaj.org/article/bf8e82b95f2e4db1bfd754107aa03b24
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Retinoids are involved in a wide range of cellular functions; as such, delivery systems for retinoids are of significant clinical interest. Here the authors review the advances in preclinical and clinical testing regarding retinoid formulations in th
Externí odkaz:
https://doaj.org/article/1e0417eeae784ebbb9edeff05e12069a
Autor:
Emanuele Azzoni, Vincent Frontera, Giorgio Anselmi, Christina Rode, Chela James, Elitza M. Deltcheva, Atanasiu S. Demian, John Brown, Cristiana Barone, Arianna Patelli, Joe R. Harman, Matthew Nicholls, Simon J. Conway, Edward Morrissey, Sten Eirik W. Jacobsen, Duncan B. Sparrow, Adrian L. Harris, Tariq Enver, Marella F.T.R. de Bruijn
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110103- (2021)
Summary: Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it
Externí odkaz:
https://doaj.org/article/a6a8f0b3c598425e993d2ab25bd647c9
Autor:
Guillermo Rodríguez-Hernández, Ana Casado-García, Marta Isidro-Hernández, Daniel Picard, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alberto Orfao, Oscar Blanco, Susana Riesco, Pablo Prieto-Matos, Francisco Javier García Criado, María Begoña García Cenador, Hanno Hock, Tariq Enver, Isidro Sanchez-Garcia, Carolina Vicente-Dueñas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ETV6-RUNX1 is almost exclusively associated with childhood B-cell acute lymphoblastic leukemia (B-ALL), but the consequences of ETV6-RUNX1 expression on cell lineage decisions during B-cell leukemogenesis are completely unknown. Clinically silent ETV
Externí odkaz:
https://doaj.org/article/b30e171f55164cd082c50a7a24ed634f