Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Tarik Smani"'
Autor:
Isaac Jardin, Sandra Alvarado, Vanesa Jimenez-Velarde, Joel Nieto-Felipe, Jose J. Lopez, Gines M. Salido, Tarik Smani, Juan A. Rosado
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Orai1 is the pore-forming subunit of the Ca2+-release activated Ca2+ channels that mediate store-operated Ca2+ entry (SOCE) in excitable and non-excitable cells. Two Orai1 forms have been identified in mammalian cells, the full-length varian
Externí odkaz:
https://doaj.org/article/4a884d7be0ba43d1933291b346da0f88
Autor:
Simon Pernot, Mercedes Tomé, Isabel Galeano-Otero, Serge Evrard, Iker Badiola, Frederic Delom, Delphine Fessart, Tarik Smani, Geraldine Siegfried, Bruno O. Villoutreix, Abdel-Majid Khatib
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
The overexpression of the immunoinhibitory receptor programmed death-1 (PD1) on T-cells is involved in immune evasion in cancer. The use of anti-PD-1/PDL-1 strategy has deeply changed the therapies of cancers and patient survival. However, their effi
Externí odkaz:
https://doaj.org/article/90571bd8e03445089bd4c69afb1017e6
Autor:
Isabel Mayoral-González, Eva M. Calderón-Sánchez, Isabel Galeano-Otero, Marta Martín-Bórnez, Encarnación Gutiérrez-Carretero, María Fernández-Velasco, Nieves Domenech, María Generosa Crespo-Leiro, Ana María Gómez, Antonio Ordóñez-Fernández, Abdelkrim Hmadcha, Tarik Smani
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 838-853 (2022)
Urocortin-2 (Ucn-2) has demonstrated cardioprotective actions against myocardial ischemia-reperfusion (I/R) injuries. Herein, we explored the protective role of Ucn-2 through microRNAs (miRNAs) post-transcriptional regulation of apoptotic and pro-fib
Externí odkaz:
https://doaj.org/article/80b1b6ec2ec24c92bf07651ea1856b7a
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
An adequate supply of oxygen (O2) is essential for most life forms on earth, making the delivery of appropriate levels of O2 to tissues a fundamental physiological challenge. When O2 levels in the alveoli and/or blood are low, compensatory adaptive r
Externí odkaz:
https://doaj.org/article/4feae3ec74e7488fa6a89e9ec83aef00
Autor:
Alejandro Berna-Erro, Jose Sanchez-Collado, Joel Nieto-Felipe, Alvaro Macias-Diaz, Pedro C. Redondo, Tarik Smani, Jose J. Lopez, Isaac Jardin, Juan A. Rosado
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1284 (2023)
The STIM family of proteins plays a crucial role in a plethora of cellular functions through the regulation of store-operated Ca2+ entry (SOCE) and, thus, intracellular calcium homeostasis. The two members of the mammalian STIM family, STIM1 and STIM
Externí odkaz:
https://doaj.org/article/d338353c87b3474ea2249b251936eedf
Autor:
Isabel Mayoral, Elisa Bevilacqua, Gorka Gómez, Abdelkrim Hmadcha, Ignacio González-Loscertales, Esther Reina, Julio Sotelo, Antonia Domínguez, Pedro Pérez-Alcántara, Younes Smani, Patricia González-Puertas, Ana Mendez, Sergio Uribe, Tarik Smani, Antonio Ordoñez, Israel Valverde
Publikováno v:
Materials Today Bio, Vol 14, Iss , Pp 100252- (2022)
Three-dimensional (3D) engineered cardiovascular tissues have shown great promise to replace damaged structures. Specifically, tissue engineering vascular grafts (TEVG) have the potential to replace biological and synthetic grafts. We aimed to design
Externí odkaz:
https://doaj.org/article/442e641e63dc4304a42882b0e2fda4e1
Autor:
Raquel Del Toro, Isabel Galeano-Otero, Elisa Bevilacqua, Francisco Guerrero-Márquez, Debora Falcon, Agustín Guisado-Rasco, Luis Díaz-de la Llera, Gonzalo Barón-Esquivias, Tarik Smani, Antonio Ordóñez-Fernández
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundPrimary percutaneous coronary intervention (PPCI) in patients with ST-segment elevation myocardial infarction (STEMI) improves the survival of patients; nevertheless, some patients develop left ventricular adverse remodeling (LVAR) a few mo
Externí odkaz:
https://doaj.org/article/5e30ad1f82bb4e24a0a420338eb91d56
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/870f4615b79b48669d17b06e52eb119e
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/ec721d4316ad40f7bf186abab398831c
Autor:
Isabel Galeano-Otero, Raquel del-Toro, Abdel-Majid Khatib, Juan Antonio Rosado, Antonio Ordóñez-Fernández, Tarik Smani
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/0439388c52f94a6f84f374e41ac69c70