Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Tarik Issad"'
Autor:
Paula Ortega-Prieto, Lucia Parlati, Fadila Benhamed, Marion Regnier, Isadora Cavalcante, Mélanie Montabord, Rachel Onifarasoaniaina, Maryline Favier, Natasa Pavlovic, Julie Magusto, Michèle Cauzac, Patrick Pagesy, Jérémie Gautheron, Chantal Desdouets, Sandra Guilmeau, Tarik Issad, Catherine Postic
Publikováno v:
JHEP Reports, Vol 6, Iss 6, Pp 101076- (2024)
Externí odkaz:
https://doaj.org/article/9628daeea97646db92182c02acc0c9bb
Autor:
Paula Ortega-Prieto, Lucia Parlati, Fadila Benhamed, Marion Regnier, Isadora Cavalcante, Mélanie Montabord, Rachel Onifarasoaniaina, Maryline Favier, Natasa Pavlovic, Julie Magusto, Michèle Cauzac, Patrick Pagesy, Jérémie Gautheron, Chantal Desdouets, Sandra Guilmeau, Tarik Issad, Catherine Postic
Publikováno v:
JHEP Reports, Vol 6, Iss 2, Pp 100878- (2024)
Background & Aims: O-GlcNAcylation is a reversible post-translational modification controlled by the activity of two enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). In the liver, O-GlcNAcylation has emerged as an important regulatory mecha
Externí odkaz:
https://doaj.org/article/6bfa0a4c47ff4e52b71882bb7a2bdb3e
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-15 (2022)
Abstract O-GlcNAcylation corresponds to the addition of N-Acetylglucosamine (GlcNAc) on serine or threonine residues of cytosolic, nuclear and mitochondrial proteins. This reversible modification is catalysed by a unique couple of enzymes, O-GlcNAc t
Externí odkaz:
https://doaj.org/article/f3d752a8191c4da1875d8a1319575557
Autor:
Victoria Jiménez-Castillo, Daniela Illescas-Barbosa, Edgar Zenteno, Beatriz Xóchitl Ávila-Curiel, Maria Cristina Castañeda-Patlán, Martha Robles-Flores, Daniel Montante-Montes De Oca, Eduardo Pérez-Campos, Anayetzin Torres-Rivera, Abdelouhab Bouaboud, Patrick Pagesy, Carlos Josué Solórzano-Mata, Tarik Issad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) is a reversible post-translational modification on serine and threonine residues of cytosolic, nuclear and mitochondrial proteins. O-GlcNAcylation level is regulated by OGT (O-GlcNAc tr
Externí odkaz:
https://doaj.org/article/5e0dde4c5d1f4e13a998f05ec6e9eace
Publikováno v:
Cells, Vol 11, Iss 11, p 1827 (2022)
O-GlcNAcylation is a reversible post-translational modification involved in the regulation of cytosolic, nuclear, and mitochondrial proteins. Only two enzymes, OGT (O-GlcNAc transferase) and OGA (O-GlcNAcase), control the attachment and removal of O-
Externí odkaz:
https://doaj.org/article/1f8373514ef44a6eab967381f9b05fbd
Autor:
Benedicte Noblet, Fadila Benhamed, InSug O-Sullivan, Wenwei Zhang, Gaëlle Filhoulaud, Alexandra Montagner, Arnaud Polizzi, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Tarik Issad, Hervé Guillou, Catherine Bernard, Terry Unterman, Catherine Postic
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102218- (2021)
Summary: TxNIP (Thioredoxin-interacting protein) is considered as a potential drug target for type 2 diabetes. Although TxNIP expression is correlated with hyperglycemia and glucotoxicity in pancreatic β cells, its regulation in liver cells has been
Externí odkaz:
https://doaj.org/article/54c26cec1c3f4bb594dcc0aa898781ca
Autor:
Tarik Issad, Tony Lefebvre
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/da2f57fc33f44123b319d4652a1b84dc
Autor:
Anne Fougerat, Xuefang Pan, Victoria Smutova, Nikolaus Heveker, Christopher W. Cairo, Tarik Issad, Bruno Larrivée, Jeffrey A. Medin, Alexey V. Pshezhetsky
Publikováno v:
Molecular Metabolism, Vol 12, Iss , Pp 76-88 (2018)
Objectives: Neuraminidase 1 (NEU1) cleaves terminal sialic acids of glycoconjugates during lysosomal catabolism. It also modulates the structure and activity of cellular surface receptors affecting diverse pathways. Previously we demonstrated that NE
Externí odkaz:
https://doaj.org/article/541e8d755b704d37851988c197c97c88
Autor:
Gaelle Filhoulaud, Fadila Benhamed, Patrick Pagesy, Caroline Bonner, Yann Fardini, Anissa Ilias, Jamileh Movassat, Anne-Françoise Burnol, Sandra Guilmeau, Julie Kerr-Conte, François Pattou, Tarik Issad, Catherine Postic
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Thioredoxin interacting protein (TxNIP), which strongly responds to glucose, has emerged as a central mediator of glucotoxicity in pancreatic β cells. TxNIP is a scaffold protein interacting with target proteins to inhibit or stimulate their activit
Externí odkaz:
https://doaj.org/article/9c5a66758ef54b9384f0c41f8fdc18bd