Zobrazeno 1 - 10
of 1 774
pro vyhledávání: '"Targeted treatment"'
Autor:
Dilara Akhoundova, Stefanie Fischer, Joanna Triscott, Marika Lehner, Phillip Thienger, Sina Maletti, Muriel Jacquet, Dinda S.H. Lubis, Lukas Bubendorf, Wolfram Jochum, Mark A. Rubin
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Catenin (Cadherin-Associated Protein), Beta 1 (CTNNB1) genomic alterations are rare in prostate cancer (PCa). Gain-of-function mutations lead to overexpression of β-catenin, with consequent hyperactivation of the Wnt/β-catenin s
Externí odkaz:
https://doaj.org/article/ab8d7da124964dd89f2c5fdc280d36be
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Highlights To summarize the mechanisms and pathophysiological features of ALI after burn. To classify the targets for the treatment of ALI. Describe the types of nanomedicines used to treat ALI. These findings suggest the prospects and outlook for na
Externí odkaz:
https://doaj.org/article/4b7daa758da040339fd198699e849f11
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 2, Pp 261-280 (2024)
Lung cancer has surpassed other types of cancer to become the primary cause of cancer-related deaths. Surgery stands as the foremost clinical treatment strategy available for tackling this condition, but it receives a low efficiency for most patients
Externí odkaz:
https://doaj.org/article/db28725b69194c7eb81390672756824a
Autor:
Emmanuella Amoako, Setor Amuzu, Emmanuel Owusu Ofori, Harry Sefoga Akligoh, Randy Tackie, Barikisu Anna Ibrahim, Emmanuel Kofi Quaye, Patrick Kafui Akakpo, Luke Adagrah Aniakwo, Bashiro Jimah, Kofi Ulzen-Appiah, David Hutchful, Aida Manu, Joyce M Ngoi, Lily Paemka, Yakubu Alhassan, Ernest Amo Obeng, Nicole Lim, Lisa Rajah, Michelle Pek, Jack Challis, Ganiyu Adebisi Rahman, Min-Han Tan, Yaw Bediako
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102100- (2024)
Purpose: Breast cancer is a major cause of cancer-related mortality among African women. The adoption of molecular genomic technologies in the management of cancer cases is limited in Africa. To provide much-needed insights on the feasibility and uti
Externí odkaz:
https://doaj.org/article/6c9ad930e71b4823ac09b9f9e44f04a4
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
PurposeEndometrial cancer (EMCA) is the most common gynecologic malignancy, and new diagnoses are increasing in the United States. Black patients are more likely to present with advanced stage, be diagnosed with high-risk uterine serous carcinoma (US
Externí odkaz:
https://doaj.org/article/057bc2e20e354f4b96dbf685ce4cc5f2
Publikováno v:
Materials Today Bio, Vol 28, Iss , Pp 101229- (2024)
Glaucoma presents a significant global health concern and affects millions of individuals worldwide and predicted a high increase in prevalence of about 111 million by 2040. The current standard treatment involves hypotensive eye drops; however, chal
Externí odkaz:
https://doaj.org/article/94b8fb13384c4a90bb0e14134a3a329a
Autor:
Mari Kyllesø Halle, Erlend Hodneland, Kari S. Wagner-Larsen, Njål G. Lura, Kristine E. Fasmer, Hege F. Berg, Tomasz Stokowy, Aashish Srivastava, David Forsse, Erling A. Hoivik, Kathrine Woie, Bjørn I. Bertelsen, Camilla Krakstad, Ingfrid S. Haldorsen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Cervical cancer (CC) is a major global health problem with 570,000 new cases and 266,000 deaths annually. Prognosis is poor for advanced stage disease, and few effective treatments exist. Preoperative diagnostic imaging is common in high-inc
Externí odkaz:
https://doaj.org/article/066bbc2abc5b4063b07e4593018e8c6a
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The Precision Oncology Platform (POP) trial represents the effort of the Portuguese Oncology Institute of Porto (IPO Porto) for joining other leading European institutions in both ‘Personalised Cancer Medicine for all EU cit
Externí odkaz:
https://doaj.org/article/5032910dc9e843a785a1d4c043032499
Autor:
Małgorzata Satora, Krzysztof Kułak, Bartłomiej Zaremba, Arkadiusz Grunwald, Paulina Świechowska-Starek, Rafał Tarkowski
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Unfortunately, ovarian cancer is still diagnosed most often only in an advanced stage and is also the most lethal gynecological cancer. Another problem is the fact that treated patients have a high risk of disease recurrence. Moreover, ovarian cancer
Externí odkaz:
https://doaj.org/article/2cf485fff507452cbdbfcdb1827d3781
Publikováno v:
Biotechnologia Acta, Vol 17, Iss 2, Pp 64-66 (2024)
Recent studies have shown that cross reacting material (CRM197), a nontoxic variant of diphtheria toxin, may play an important role in treating cancers with poor prognoses. Doxorubicin-hydrochloride (DOX) is an antineoplastic prescription medicine fo
Externí odkaz:
https://doaj.org/article/0cb81c933a0e4ccd92b5c9e5255a0aeb