Zobrazeno 1 - 10
of 10 309
pro vyhledávání: '"Targeted therapies"'
Publikováno v:
Case Reports in Oncology, Vol 17, Iss 1, Pp 1124-1130 (2024)
Introduction: Clear cell renal cell carcinoma (ccRCC), the most common type of kidney cancer in adults, presents significant challenges owing to its resistance to conventional therapies. Standard treatment primarily revolves around surgical methods,
Externí odkaz:
https://doaj.org/article/076105e65efc4472a9fc223c00e0aef4
Publikováno v:
Journal of Indian Academy of Oral Medicine and Radiology, Vol 36, Iss 3, Pp 254-258 (2024)
Background: Oral mucositis (OM) is an acute debilitating side effects of chemoradiotherapy (CRT) in head and neck cancer (HNC) patients. Salivary biomarkers are noninvasive and aid in early diagnosis and disease prevention. Objective: This study anal
Externí odkaz:
https://doaj.org/article/a8d59a1537ae41339e5189d7261c86df
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-4 (2024)
Abstract Multiple classes of therapies targeting claudin-18 isoform 2 (CLDN18.2) are under development for the treatment of advanced gastroesophageal adenocarcinoma and other solid tumors. At the 2024 American Society of Clinical Oncology (ASCO) Annu
Externí odkaz:
https://doaj.org/article/7c852dae49844599adeca9f938191bc2
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Vol 7, Iss 3, Pp 159-167 (2024)
Introduction: In targeted therapies and immunotherapies, the occurrence of low-grade (e.g., grade 1–2) toxicities (LGT) is common, while dose-limiting toxicities (DLT) are relatively rare. As a result, conventional phase I trial designs, solely bas
Externí odkaz:
https://doaj.org/article/a95808ca83c7417cbe37e7c86e72bee8
Publikováno v:
Bioelectronic Medicine, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract Bioelectronic Medicine (BEM), which uses implantable electronic medical devices to interface with electrically active tissues, aspires to revolutionize the way we understand and fight disease. By leveraging knowledge from microelectronics, m
Externí odkaz:
https://doaj.org/article/5cf0ed57b8a84a2fb38424fa944704b6
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Mitochondria are crucial organelles responsible for energy generation in eukaryotic cells. Oxidative stress, calcium disorders, and mitochondrial DNA abnormalities can all cause mitochondrial dysfunction. It is now well documented that mitoc
Externí odkaz:
https://doaj.org/article/a60bbc4222c145028c4dde0b66f16be5
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-19 (2024)
Abstract Helicobacter pylori infection is involved in gastric diseases such as peptic ulcer and adenocarcinoma. Approved antibiotherapies still fail in 10 to 40% of the infected patients and, in this scenario, targeted nanotherapeutics emerged as pow
Externí odkaz:
https://doaj.org/article/1b23ba4f22d048b1a69a3053f682d34f
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 11, Pp 1495-1505 (2024)
Jianming Yang,1,* Yu Zhang,2,* Yewu Chen,1,* Yang Yang,1,3 Yinan Deng1 1Department of Hepatic Surgery and Liver Transplantation Center, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People’s Republic of China; 2Dep
Externí odkaz:
https://doaj.org/article/8909b1f52f3842ec89802bf0fd20d819
Autor:
Lei Cao, Wencong Tian, Yongjie Zhao, Peng Song, Jia Zhao, Chuntao Wang, Yanhong Liu, Hong Fang, Xingqiang Liu
Publikováno v:
Global Medical Genetics, Vol 11, Iss 04, Pp 251-262 (2024)
Although gastrointestinal stromal tumors (GISTs) has been reported in patients of all ages, its diagnosis is more common in elders. The two most common types of mutation, receptor tyrosine kinase (KIT) and platelet-derived growth factor receptor a (P
Externí odkaz:
https://doaj.org/article/27a45c5ff0d545c584eec6ddde3be173
Autor:
Esther Redin, Harsha Sridhar, Yingqian A. Zhan, Barbara Pereira Mello, Hong Zhong, Vidushi Durani, Amin Sabet, Parvathy Manoj, Irina Linkov, Juan Qiu, Richard P. Koche, Elisa de Stanchina, Maider Astorkia, Doron Betel, Álvaro Quintanal-Villalonga, Charles M. Rudin
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-19 (2024)
Abstract Introduction Small Cell Lung Cancer (SCLC) can be classified into transcriptional subtypes with distinct degrees of neuroendocrine (NE) differentiation. Recent evidence supports plasticity among subtypes with a bias toward adoption of low-NE
Externí odkaz:
https://doaj.org/article/863d3755b2ea4eb2a85f6bb551cf6172