Zobrazeno 1 - 10
of 482
pro vyhledávání: '"Targeted drug delivery system"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Two strategies were employed to modify the performance of the nano-niosome drug delivery system. Initially, the surface of the nano-niosomes underwent modification through the inclusion of polyethylene glycol, thereby altering its properties
Externí odkaz:
https://doaj.org/article/f32bc461d7484bce82e112943bf80127
Autor:
Huating Huang, Aqian Chang, Hulinyue Peng, Jing Liu, Aina Yao, Yidan Ruan, Pingzhi Zhang, Tieshan Wang, Changhai Qu, Xingbin Yin, Jian Ni, Xiaoxv Dong
Publikováno v:
Journal of Science: Advanced Materials and Devices, Vol 9, Iss 3, Pp 100755- (2024)
Polyphyllin II (PPII) has been proven to have significant anti-liver cancer activity, but its application is limited by poor solubility, low bioavailability, and systemic toxicity caused by non-selectivity. To address the above problem, PPII was enca
Externí odkaz:
https://doaj.org/article/63e95eb5453b43f6a25185755dfd1102
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100943- (2024)
Inflammatory bowel diseases (IBD) significantly contribute to high mortality globally and negatively affect patients' qualifications of life. The gastrointestinal tract has unique anatomical characteristics and physiological environment limitations.
Externí odkaz:
https://doaj.org/article/0f5feeb60ca8486ead6befa37a29342a
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 4275-4311 (2023)
Mian Huang,1 Bing-Tao Zhai,1,2 Yu Fan,3 Jing Sun,1 Ya-Jun Shi,1 Xiao-Fei Zhang,1 Jun-Bo Zou,1 Jia-Wen Wang,1 Dong-Yan Guo1,4 1School of Pharmacy, Shaanxi University of Chinese Medicine, Xi’an, 712046, People’s Republic of China; 2State Key Labora
Externí odkaz:
https://doaj.org/article/49d244ab04d34b2d8a9715ea2641e250
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 2, Pp 101333- (2024)
Inflammatory bowel disease (IBD), marked by chronic gastrointestinal tract inflammation, poses a significant global medical challenge. Current treatments for IBD, including corticosteroids, immunomodulators, and biologics, often require frequent syst
Externí odkaz:
https://doaj.org/article/56940ac35571497a94cb506fbc073163
Publikováno v:
MedComm – Biomaterials and Applications, Vol 2, Iss 4, Pp n/a-n/a (2023)
Abstract The growing need for innovative drug delivery systems has led to extensive research to address the limitations associated with conventional dosage forms. Lipid nanoparticles have become prominent as frontline nanocarriers for the delivery of
Externí odkaz:
https://doaj.org/article/730bb52e60724a0b92a25f09bb6b41a6
Publikováno v:
Bioactive Materials, Vol 23, Iss , Pp 69-79 (2023)
Background: Immunosuppressive M2 macrophages in the tumor microenvironment (TME) can mediate the therapeutic resistance of tumors, and seriously affect the clinical efficacy and prognosis of tumor patients. This study aims to develop a novel drug del
Externí odkaz:
https://doaj.org/article/880ef50a0373461fb0c77c70c69e2ee6
Publikováno v:
Nanomaterials, Vol 14, Iss 7, p 557 (2024)
Colorectal cancer (CRC) is a common malignant tumor, and traditional treatments include surgical resection and radiotherapy. However, local recurrence, distal metastasis, and intestinal obstruction are significant problems. Oral nano-formulation is a
Externí odkaz:
https://doaj.org/article/1f1a23b74d10406b8dffb0f34b7f5564
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115331- (2023)
Elemene (ELE) is a group of broad-spectrum anticancer active ingredients with low toxicity extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and Curcuma Radix, which can exert antitumour activities by regulating various si
Externí odkaz:
https://doaj.org/article/0667bf6e4ead4bc8bc4d39d0a5d0a48a
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e20280- (2023)
Notoginsenoside R1 (R1), which originated from the rhizomes and roots of Panax notoginseng, is classified as a Biopharmaceutical Classification System class III drug with good solubility but poor oral absorption. Although R1 can alleviate the inflamm
Externí odkaz:
https://doaj.org/article/f1a94835329f49dc92f43d3911c7a8e0