Zobrazeno 1 - 10
of 579
pro vyhledávání: '"Target delivery"'
Autor:
Jing Rong, Tongtong Liu, Xiujuan Yin, Min Shao, Kun Zhu, Bin Li, Shiqi Wang, Yujie Zhu, Saisai Zhang, Likang Yin, Qi Liu, Xiao Wang, Lei Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background Camptothecin (CPT) is one of the frequently used small chemotherapy drugs for treating hepatocellular carcinoma (HCC), but its clinical application is limited due to severe toxicities and acquired resistance. Combined chemo-gene t
Externí odkaz:
https://doaj.org/article/00973d5bdfdf4dbcb02ff1a80e8aad77
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Oral cancer is the most common malignant tumor of the head and neck, and 90% of cases are oral squamous cell carcinoma (OSCC). Chemotherapy is an important component of comprehensive treatment for OSCC. However, the clinical treat
Externí odkaz:
https://doaj.org/article/67fa1fc10fd44e5cb882aead6a03e38b
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The morbidity and mortality of gastrointestinal tumours remain high worldwide. Surgical resection is currently the most critical radical therapeutic schedule, while postoperative complications and sentinel lymph node (SLN) identification are
Externí odkaz:
https://doaj.org/article/3a9d2ad2cb704d90be4749d2df09bdbe
Publikováno v:
Frontiers in Robotics and AI, Vol 11 (2024)
Oral administration is a convenient drug delivery method in our daily lives. However, it remains a challenge to achieve precise target delivery and ensure the efficacy of medications in extreme environments within the digestive system with complex en
Externí odkaz:
https://doaj.org/article/986ca5074c294abaa3e3a0e5f5d8d740
Autor:
Asifa Saif, Laiba Anjum, Zargham Faisal, Noor Akram, Yasir Abbas Shah, Rushba Irfan, Farhan Saeed, Muhammad Afzaal, Mohd Asif Shah
Publikováno v:
International Journal of Food Properties, Vol 26, Iss 2, Pp 2866-2880 (2023)
ABSTRACTThe target delivery of sensitive ingredients is affected by various factors including hostile processing, and environmental and storage conditions. These factors are significant challenges in the target delivery and stability of bioactive com
Externí odkaz:
https://doaj.org/article/181dab340c2f4358aff431412b88b49b
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-24 (2023)
Abstract Background Methotrexate (MTX) is a common chemotherapeutic drug that inhibits DNA synthesis and induces apoptosis. Treatment with MTX increased CD73 expression, which leads to higher levels of extracellular adenosine. Adenosine levels are al
Externí odkaz:
https://doaj.org/article/7b669a87c6804390b2f31be14ea70ca3
Publikováno v:
Marine Drugs, Vol 22, Iss 7, p 314 (2024)
α-Conotoxins, as selective nAChR antagonists, can be valuable tools for targeted drug delivery and fluorescent labeling, while conotoxin-drug or conotoxin-fluorescent conjugates through the disulfide bond are rarely reported. Herein, we demonstrate
Externí odkaz:
https://doaj.org/article/307e7a732faf41aa9897cb8ef3eb34a6
Autor:
Li Zhu, Hongjiao Li, Jiyu Li, Yuan Zhong, Shuai Wu, Meng Yan, Sheng Ni, Kun Zhang, Guixue Wang, Kai Qu, Deqin Yang, Xian Qin, Wei Wu
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-22 (2023)
Abstract A disorder of cholesterol homeostasis is one of the main initiating factors in the progression of atherosclerosis (AS). Metabolism and removal of excess cholesterol facilitates the prevention of foam cell formation. However, the failure of t
Externí odkaz:
https://doaj.org/article/0240787e5ef94c2db06cb70884c7bf11
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 1, Pp 200788- (2024)
Lung cancer’s intractability is enhanced by its frequent resistance to (chemo)therapy and often high relapse rates that make it the leading cause of cancer death worldwide. Improvement of therapy efficacy is a crucial issue that might lead to a sig
Externí odkaz:
https://doaj.org/article/5afb62fadfc04be6ac738d2d20d12f03
Autor:
Qingzhi Ji, Huimin Zhu, Yuting Qin, Ruiya Zhang, Lei Wang, Erhao Zhang, Xiaorong Zhou, Run Meng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Albumin is derived from human or animal blood, and its ability to bind to a large number of endogenous or exogenous biomolecules makes it an ideal drug carrier. As a result, albumin-based drug delivery systems are increasingly being studied. With the
Externí odkaz:
https://doaj.org/article/b7c906bb72c641cd849a29e5c7580ea5