Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Tareq Hameduh"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5443-5454 (2021)
Cancer cells can escape the effects of chemotherapy through mutations and upregulation of a tyrosine kinase protein called the epidermal growth factor receptor (EGFR). In the past two decades, four generations of tyrosine kinase inhibitors targeting
Externí odkaz:
https://doaj.org/article/1dff5357db5b4cefbee8db849a4fe23d
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 3494-3506 (2020)
Homology modeling is a method for building protein 3D structures using protein primary sequence and utilizing prior knowledge gained from structural similarities with other proteins. The homology modeling process is done in sequential steps where seq
Externí odkaz:
https://doaj.org/article/e66a15d115e346a7b0b42efec95f2789
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 5443-5454 (2021)
Computational and Structural Biotechnology Journal. 2021, vol. 19, issue 1, p. 5443-5454.
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal. 2021, vol. 19, issue 1, p. 5443-5454.
Computational and Structural Biotechnology Journal
Graphical abstract
Highlights • EGFR kinase C-helix moves relate to side chain rotamers of 43 residues. • Rotamer changes formed several clusters as part of two major information relays. • Relay-IN identifies rotamers in active C-helix-IN/
Highlights • EGFR kinase C-helix moves relate to side chain rotamers of 43 residues. • Rotamer changes formed several clusters as part of two major information relays. • Relay-IN identifies rotamers in active C-helix-IN/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6db4cc9de9d355e6c774cb0c19b9da6
https://doi.org/10.1016/j.csbj.2021.09.026
https://doi.org/10.1016/j.csbj.2021.09.026
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 23(10)
Lysine-specific demethylase is a demethylase enzyme that can remove methyl groups from histones H3K4me1/2 and H3K9me1/2. It is expressed in many cancers, where it impedes differentiation and contributes to cancer cell proliferation, cell metastasis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c73c15ae2d4f9ba55d731e15309a2321
https://pubmed.ncbi.nlm.nih.gov/36308380
https://pubmed.ncbi.nlm.nih.gov/36308380
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3494-3506 (2020)
Computational and Structural Biotechnology Journal. 2021, vol. 18, issue 1, p. 3494-3506.
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 3494-3506 (2020)
Computational and Structural Biotechnology Journal. 2021, vol. 18, issue 1, p. 3494-3506.
Homology modeling is a method for building protein 3D structures using protein primary sequence and utilizing prior knowledge gained from structural similarities with other proteins. The homology modeling process is done in sequential steps where seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7227f5d3a5b165e05be9e7cc63be32
https://doi.org/10.1016/j.csbj.2020.11.007
https://doi.org/10.1016/j.csbj.2020.11.007
Autor:
Sara AlBayyari, Malek Zihlif, Hiba Zalloum, Tareq Hameduh, Bashaer Abu-Irmaileh, Waleed A. Zalloum, Mohammad S. Mubarak, Tuka AbuThiab
Publikováno v:
Breast cancer (Tokyo, Japan). 27(2)
Breast cancer is one of the most lethal types of cancer in women worldwide. The human epidermal growth factor receptor 2 (HER2) is considered as a validated target in breast cancer therapy. Previously, we have used quantitative structure activity rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30162dca2e6913fbfd1746f85b495727
https://pubmed.ncbi.nlm.nih.gov/31559601
https://pubmed.ncbi.nlm.nih.gov/31559601
Autor:
'Tareq Hameduh
Publikováno v:
Michal Mokry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::f621a7825382bf113e49f6ed5a14ef5e