Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Tarek Sammakia"'
Publikováno v:
Encyclopedia of Reagents for Organic Synthesis. :1-12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3355c1a6fbccdd15e54e2dde6f1b6bd
https://doi.org/10.1002/047084289x.rd017.pub2
https://doi.org/10.1002/047084289x.rd017.pub2
Insulin has been commonly adopted as a peptide drug to treat diabetes given its ability to facilitate the uptake of glucose from the blood. The development of oral insulin remains elusive over decades owing to its susceptibility to the enzymes in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c5421463dc4a34b6a2778feea492bb
https://doi.org/10.26434/chemrxiv-2021-l2zd5-v2
https://doi.org/10.26434/chemrxiv-2021-l2zd5-v2
A rigid tetracene dimer with a substantial interchromophore distance has been prepared through the application of the recently developed catalytic arene-norbornene annulation (CANAL) reaction. An iterative cycloaddition route was found to be unsucces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e1c6f0bdc04c71a7ba5a7181635bc64
https://doi.org/10.26434/chemrxiv.14412200.v1
https://doi.org/10.26434/chemrxiv.14412200.v1
Publikováno v:
Organic Letters. 20:457-460
An improved, modular synthesis of rigid, geometrically well-defined, alkyne-substituted tetracene (1) and pentacene (2) dimers is reported. The synthesis is rooted in sequential Diels-Alder reactions of a norbornyl tetraene with triisopropylsilylacet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4914cd9793417c34ec232fffdb1bb174
https://doi.org/10.1021/acs.orglett.7b03817
https://doi.org/10.1021/acs.orglett.7b03817
Publikováno v:
The Journal of Organic Chemistry. 82:4866-4874
We report the first synthesis of norbornyl-bridged acene dimers (2 and 3) with well-defined and controlled spatial relationships between the acene chromophore subunits. We employ a modular 2-D strategy wherein the central module, common to all our co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ebd265fd652b87ccca617a950828d01
https://doi.org/10.1021/acs.joc.7b00602
https://doi.org/10.1021/acs.joc.7b00602
Autor:
Tarek Sammakia, Jacob A. Greenberg
Publikováno v:
The Journal of Organic Chemistry. 82:3245-3251
The reaction of tert-butyl esters with SOCl2 at room temperature provides acid chlorides in unpurified yields of 89% or greater. Benzyl, methyl, ethyl, and isopropyl esters are essentially unreactive under these conditions, allowing for the selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b188f45b3d09b7da2d9dff94a082c797
https://doi.org/10.1021/acs.joc.6b02931
https://doi.org/10.1021/acs.joc.6b02931
Structurally well-defined TIPS-acetylene substituted tetracene (TIPS BT1') and pentacene (TIPS BP1') dimers utilizing a [2.2.1] bicyclic norbornyl bridge have been studied -primarily using time-resolved spectroscopic methods - to uncover mechanistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3539fda70c86889efa208fcf7bdddafe
Publikováno v:
Organic Letters. 17:5196-5199
The selective alkyl lithium-induced ring opening of 1,3-di-isopropylsilylenes is described. The reaction affords a differentially substituted 1,3-diol bearing a silane that resides at the oxygen in the more sterically demanding position. The reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4229c4e6bf40998d4e88b6d21f48afd7
https://doi.org/10.1021/acs.orglett.5b02529
https://doi.org/10.1021/acs.orglett.5b02529
Autor:
Tarek Sammakia, William T. Hartwig
Publikováno v:
The Journal of organic chemistry. 82(1)
The use of bulky Lewis acids, aluminum tris(2,6-diphenylphenoxide) (ATPH) and aluminum tris(2,6-di-2-naphthylphenoxide) (ATNP), in the doubly vinylogous aldol reaction between methyl-5-methyl-2-furoate and aldehydes or ketones is described. These rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0720f4bbc320bcc8594ff93f9ce1337e
https://pubmed.ncbi.nlm.nih.gov/27966966
https://pubmed.ncbi.nlm.nih.gov/27966966
Publikováno v:
ChemInform. 47
The selective alkyl lithium-induced ring opening of 1,3-di-isopropylsilylenes is described. The reaction affords a differentially substituted 1,3-diol bearing a silane that resides at the oxygen in the more sterically demanding position. The reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1914f96d4458dd797911bbd9a698e8e9
https://doi.org/10.1002/chin.201613038
https://doi.org/10.1002/chin.201613038