Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Tarek M. Fahmy"'
Autor:
David A. Horwitz, Aijing Liu, Sean Bickerton, Giuseppe Castaldo, Giuseppe Matarese, Tarek M. Fahmy, Antonio La Cava
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We recently reported that the treatment with nanoparticles (NPs) loaded with tolerogenic cytokines suppressed the manifestations of lupus-like disease induced by the transfer of donor CD4+ T cells from DBA/2 mice into (C57BL/6 × DBA/2)F1 (BDF1) mice
Externí odkaz:
https://doaj.org/article/8c0395ecdfc14b81aad71aee7f2c88ad
Autor:
Jing-Wei Zhao, Sean C. Dyson, Christina Kriegel, Pam Tyers, Xiaoling He, Tarek M. Fahmy, Su M. Metcalfe, Roger A. Barker
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 10, Pp 1193-1203 (2014)
The endogenous reparative capacity of the adult human brain is low, and chronic neurodegenerative disorders of the central nervous system represent one of the greatest areas of unmet clinical need in the developing world. Novel therapeutic strategies
Externí odkaz:
https://doaj.org/article/cd5c7eae99284186a78ab9fa4c49232b
Publikováno v:
International Journal of Biomaterials, Vol 2009 (2009)
Current efforts in surface functionalization have not produced a robust technique capable of creating specific two-dimensional microscale geometrical arrays composed of multiple proteins. Such a capability is desirable for engineering substrates in s
Externí odkaz:
https://doaj.org/article/6f92fbf3d01441eab9ae766dc74f78b7
Autor:
Ryosuke Taniguchi, Yuichi Ohashi, Jung Seok Lee, Haidi Hu, Luis Gonzalez, Weichang Zhang, John Langford, Yutaka Matsubara, Bogdan Yatsula, George Tellides, Tarek M. Fahmy, Katsuyuki Hoshina, Alan Dardik
Publikováno v:
Arterioscler Thromb Vasc Biol
Background: Arteriovenous fistulae (AVF) are the gold standard for vascular access for hemodialysis. Although the vein must thicken and dilate for successful hemodialysis, excessive wall thickness leads to stenosis causing AVF failure. Since TGF-β (
Autor:
Michael D McHugh, Tarek M. Fahmy, Sean Bickerton, Jung Seok Lee, Ragy Ragheb, Rabib Chaudhury, David A. Horwitz, Shihan N. Khan, Alyssa Siefert, Robert M. Samstein, Karlo Perica, José M. Carballido, Gerald Rea, Dongin Kim, Hyun Bong Park, Jason M. Criscione, Patrick Han
Publikováno v:
Nature Biomedical Engineering. 5:983-997
Oral formulations of insulin are typically designed to improve its intestinal absorption and increase its blood bioavailability. Here we show that polymerized ursodeoxycholic acid, selected from a panel of bile-acid polymers and formulated into nanop
Autor:
Tarek M. Fahmy, Shari Yosinski, Rabib Chaudhury, Mark A. Reed, Zachary Kobos, Jung Seok Lee, Patrick Han
Publikováno v:
ACS Nano. 14:8646-8657
The sensitivity and speed with which the immune system reacts to host disruption is unrivaled by any detection method for pathogenic biomarkers or infectious signatures. Engagement of cellular immunity in response to infections or cancer is contingen
Publikováno v:
Trends Immunol
During homeostasis, interactions between tolerogenic dendritic cells (DCs), self-reactive T cells, and T regulatory cells (Tregs) contribute to maintaining mammalian immune tolerance. In response to infection, immunogenic DCs promote the generation o
Publikováno v:
Arthritis & Rheumatology. 71:632-640
Objective To develop a nanoparticle (NP) platform that can expand both CD4+ and CD8+ Treg cells in vivo for the suppression of autoimmune responses in systemic lupus erythematosus (SLE). Methods Poly(lactic-co-glycolic acid) (PLGA) NPs encapsulating
Autor:
Tarek M. Fahmy, Jong Hoon Choi, Byul Hur, Jung Seok Lee, Steve Vuong, Eunsoo Yoo, Patrick Han, Ngoc Ha Hoang, Dongin Kim, Kyung Taek Oh
Publikováno v:
ACS Applied Bio Materials. 1:1927-1941
Oncothermia, a special form of hyperthermia for oncological purposes, has been widely shown to be an effective mode of cancer therapy. However, its adoption among standard therapeutic practices has been limited by constraints in delivering sufficient
Autor:
Daniel P. Petrylak, Tarek M. Fahmy, Peter G. Schulam, Darryl T. Martin, Jung Seok Lee, Peter A. Humphrey, Gigi Galiana, Preston C. Sprenkle, Robert M. Weiss, Jeffery C. Weinreb, Qiang Liu
Publikováno v:
Nanomedicine : nanotechnology, biology, and medicine. 40
Magnetic resonance is a key imaging tool for the detection of prostate cancer; however, better tools focusing on cancer specificity are required to distinguish benign from cancerous regions. We found higher expression of claudin-3 (CLDN-3) and -4 (CL