Výsledky vyhledávání - "Tarek El-Hamoly"

Akademický článek

Development and bioevaluation of controlled release 5-aminoisoquinoline nanocomposite: a synergistic anticancer activity against human colon cancer

Autor: Alaa AL-Rahman Gamal, El-Sayed Mahmoud El-Sayed, Tarek El-Hamoly, Heba Kahil

Publikováno v: AIMS Biophysics, Vol 9, Iss 1, Pp 21-41 (2022)

The current study presents a bimodal therapeutic platform for cancer treatment. Bimodal implies that the presented drug loaded core-shell structure is capable of elevating the tumor tissue temperature (hyperthermia) through the superparamagnetic iron

Externí odkaz: https://doaj.org/article/d4890fbf0a364085827c956b2a66c82f

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Akademický článek

OGG1 Inhibition Reduces Acinar Cell Injury in a Mouse Model of Acute Pancreatitis

Autor: Zoltán Hajnády, Máté Nagy-Pénzes, Máté A. Demény, Katalin Kovács, Tarek El-Hamoly, József Maléth, Péter Hegyi, Zsuzsanna Polgár, Csaba Hegedűs, László Virág

Publikováno v: Biomedicines, Vol 10, Iss 10, p 2543 (2022)

Acute pancreatitis (AP) is a potentially life-threatening gastrointestinal disease with a complex pathology including oxidative stress. Oxidative stress triggers oxidative DNA lesions such as formation of 7,8-dihydro-8-oxo-2′-oxoguanine (8-oxoG) an

Externí odkaz: https://doaj.org/article/748ab7fdedcd4f0b9af3c659885fb2b5

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Akademický článek

Tricetin Reduces Inflammation and Acinar Cell Injury in Cerulein-Induced Acute Pancreatitis: The Role of Oxidative Stress-Induced DNA Damage Signaling

Autor: Máté Nagy-Pénzes, Zoltán Hajnády, Zsolt Regdon, Máté Á. Demény, Katalin Kovács, Tarek El-Hamoly, József Maléth, Péter Hegyi, Csaba Hegedűs, László Virág

Publikováno v: Biomedicines, Vol 10, Iss 6, p 1371 (2022)

Acute pancreatitis (AP) poses a worldwide challenge due to the growing incidence and its potentially life-threatening course and complications. Specific targeted therapies are not available, prompting the identification of new pathways and novel ther

Externí odkaz: https://doaj.org/article/97333ce3f604486d964281b5d7a01d58

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Akademický článek

Potential effects of ursodeoxycholic acid on accelerating cutaneous wound healing.

Autor: Tarek El-Hamoly, Sahar S Abd El-Rahman, Megahed Al-Abyad

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0226748 (2019)

Among the initial responses to skin injury, triggering inflammatory mediators and modifying oxidative status provide the necessary temple for the subsequent output of a new functional barrier, fibroplasia and collagen deposition, modulated by NF-κB

Externí odkaz: https://doaj.org/article/f27c005206964bfe8899f5608f1beb3d

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Akademický článek

L-thyroxine modifies nephrotoxicity by regulating the apoptotic pathway: The possible role of CD38/ADP-ribosyl cyclase-mediated calcium mobilization.

Autor: Tarek El-Hamoly, Dina M El-Sharawy, Marwa S El Refaye, Sahar S Abd El-Rahman

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184157 (2017)

Thyroid hormones are well-established as a key regulator of many cellular metabolic pathways developed in various pathogeneses. Here, we dedicated the current work to investigate the role of thyroid hormone analogue (L-thyroxine, L-TH) in regulating

Externí odkaz: https://doaj.org/article/f06ec078d37c445a870de53ddddf24eb

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