Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Taras Velychko"'
Autor:
Iga K. Mieczkowska, Garyfallia Pantelaiou-Prokaki, Evangelos Prokakis, Geske E. Schmidt, Lukas C. Müller-Kirschbaum, Marcel Werner, Madhobi Sen, Taras Velychko, Katharina Jannasch, Christian Dullin, Joanna Napp, Klaus Pantel, Harriet Wikman, Maria Wiese, Christof M. Kramm, Frauke Alves, Florian Wegwitz
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Abstract Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the ba
Externí odkaz:
https://doaj.org/article/20c0c3f49a9e491b86d9b16315f3a86d
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Le Xiong, Erik A Tolen, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife, Vol 11 (2022)
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Externí odkaz:
https://doaj.org/article/1d5965331e63415ea1891c5a5bf6e818
Autor:
Julio Abril-Garrido, Christian Dienemann, Frauke Grabbe, Taras Velychko, Michael Lidschreiber, Haibo Wang, Patrick Cramer
Publikováno v:
Molecular Cell.
Autor:
Caitlin M. MacCarthy, Vikas Malik, Guangming Wu, Taras Velychko, Gal Keshet, Ralf Jauch, Vlad Cojocaru, Hans R. Schöler, Sergiy Velychko
The discovery of induced pluripotent stem cell (iPSC) technology by Shinya Yamanaka has truly enabled the stem cell field. After 16 years of intense research, the delivery methods and culture media have improved but the original factors—Oct4, Sox2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c34ea177b5561bcfb4addc8cf372d0e0
https://doi.org/10.1101/2022.09.23.509242
https://doi.org/10.1101/2022.09.23.509242
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca9e19f99e30a5e867714e090f2dbfe3
https://doi.org/10.7554/elife.71533.sa2
https://doi.org/10.7554/elife.71533.sa2
Autor:
Livia Caizzi, Patrick Cramer, Takayuki Nojima, Shona Murphy, Justyna Zaborowska, Michael Tellier, Daniel Blears, Björn Schwalb, Eusra Mohammad, Ivan Ferrer-Vicens, Taras Velychko
Publikováno v:
Nucleic Acids Research
Cyclin-dependent kinase 12 (CDK12) phosphorylates the carboxyl-terminal domain (CTD) of RNA polymerase II (pol II) but its roles in transcription beyond the expression of DNA damage response genes remain unclear. Here, we have used TT-seq and mNET-se
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
Autor:
Erik A Tolen, Le Xiong, Jinmi Choi, Sergiy Velychko, Livia Caizzi, Taras Velychko, Kenjiro Adachi, Caitlin M MacCarthy, Michael Lidschreiber, Patrick Cramer, Hans R Schöler
Publikováno v:
eLife.
eLife
eLife
The transcription factor Oct4 is essential for the maintenance and induction of stem cell pluripotency, but its functional roles are not fully understood. Here, we investigate the functions of Oct4 by depleting and subsequently recovering it in mouse
Autor:
Garyfallia Pantelaiou-Prokaki, Taras Velychko, Maria Wiese, Christian Dullin, Iga K Mieczkowska, Florian Wegwitz, Katharina Jannasch, Geske Schmidt, Joanna Napp, Klaus Pantel, Frauke Alves, Harriet Wikman, Marcel Werner, Madhobi Sen, Lukas C Müller-Kirschbaum, Evangelos Prokakis, Christof M. Kramm
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development of targeted therapies have greatly improved the survival rate of BC patients. However, the basal-like
Autor:
Damien J. Downes, Alastair L. Smith, Magdalena A. Karpinska, Taras Velychko, Kevin Rue-Albrecht, David Sims, Thomas A. Milne, James O. J. Davies, A. Marieke Oudelaar, Jim R. Hughes
Chromosome conformation capture (3C) methods measure the spatial proximity between DNA elements in the cell nucleus. Many methods have been developed to sample 3C material, including the Capture-C family of protocols. Capture-C methods use oligonucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7690bf66642b46af4fad476955e337ca
https://ora.ox.ac.uk/objects/uuid:a4c28a0c-f88b-41ba-a110-3a119c2a9c3c
https://ora.ox.ac.uk/objects/uuid:a4c28a0c-f88b-41ba-a110-3a119c2a9c3c
Autor:
Damien J, Downes, Alastair L, Smith, Magdalena A, Karpinska, Taras, Velychko, Kevin, Rue-Albrecht, David, Sims, Thomas A, Milne, James O J, Davies, A Marieke, Oudelaar, Jim R, Hughes
Publikováno v:
Nature protocols. 17(2)
Chromosome conformation capture (3C) methods measure the spatial proximity between DNA elements in the cell nucleus. Many methods have been developed to sample 3C material, including the Capture-C family of protocols. Capture-C methods use oligonucle