Výsledky vyhledávání - "Taras Tuczewycz"

Akademický článek

Optimization of dose and route of administration of the P‐glycoprotein inhibitor, valspodar (PSC‐833) and the P‐glycoprotein and breast cancer resistance protein dual‐inhibitor, elacridar (GF120918) as dual infusion in rats

Autor: Christopher Rowbottom, Alicia Pietrasiewicz, Taras Tuczewycz, Richard Grater, Daniel Qiu, Sudarshan Kapadnis, Patrick Trapa

Publikováno v: Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)

Abstract Transporters can play a key role in the absorption, distribution, metabolism, and excretion of drugs. Understanding these contributions early in drug discovery allows for more accurate projection of the clinical pharmacokinetics. One method

Externí odkaz: https://doaj.org/article/103f00bec9d940f988399c1ce77485f6

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Autor: Sudarshan Kapadnis, Patrick Trapa, Richard Grater, Daniel Qiu, Taras Tuczewycz, Christopher Rowbottom, Alicia Pietrasiewicz

Publikováno v: Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 9, Iss 2, Pp n/a-n/a (2021)

Transporters can play a key role in the absorption, distribution, metabolism, and excretion of drugs. Understanding these contributions early in drug discovery allows for more accurate projection of the clinical pharmacokinetics. One method to assess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a2ee10faed30def67aa2b2127bd820
http://europepmc.org/articles/PMC7931226

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