Genetic analyses involving interactions between the ergosterol biosynthetic enzymes, lanosterol synthase (Erg7p) and 3-ketoreductase (Erg27p), in the yeast Saccharomyces cerevisiae

Autor: Teske, B., Taramino, S., Bhuiyan, M.S.A., Kumaraswami, N.S., Randall, S.K., Barbuch, R., Eckstein, J., Balliano, G., Bard, M.

Publikováno v: In BBA - Molecular and Cell Biology of Lipids 2008 1781(8):359-366

4-Methylzymosterone and Other Intermediates of Sterol Biosynthesis from Yeast Mutants Engineered in the ERG27 Gene Encoding 3-Ketosteroid Reductase.

Autor: Ferrante T; Department of Science and Drug Technology, University of Torino, Via P. Giuria 9, 10125, Turin, Italy., Barge A; Department of Science and Drug Technology, University of Torino, Via P. Giuria 9, 10125, Turin, Italy., Taramino S; Department of Science and Drug Technology, University of Torino, Via P. Giuria 9, 10125, Turin, Italy., Oliaro-Bosso S; Department of Science and Drug Technology, University of Torino, Via P. Giuria 9, 10125, Turin, Italy. simona.oliaro@unito.it., Balliano G; Department of Science and Drug Technology, University of Torino, Via P. Giuria 9, 10125, Turin, Italy. gianni.balliano@unito.it.

Publikováno v: Lipids [Lipids] 2016 Sep; Vol. 51 (9), pp. 1103-13. Date of Electronic Publication: 2016 Jul 15.

Characterization of a mutation that results in independence of oxidosqualene cyclase (Erg7) activity from the downstream 3-ketoreductase (Erg27) in the yeast ergosterol biosynthetic pathway.

Autor: Layer JV; Biology Department, Indiana University-Purdue University, Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202, USA., Barnes BM, Yamasaki Y, Barbuch R, Li L, Taramino S, Balliano G, Bard M

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2013 Feb; Vol. 1831 (2), pp. 361-9. Date of Electronic Publication: 2012 Sep 27.

Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts.

Autor: Taramino S; Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, Via Pietro Giuria 9, Torino, Italy., Teske B, Oliaro-Bosso S, Bard M, Balliano G

Publikováno v: Biochimica et biophysica acta [Biochim Biophys Acta] 2010 Nov; Vol. 1801 (11), pp. 1232-7. Date of Electronic Publication: 2010 Jul 24.

Oxidosqualene cyclase from Saccharomyces cerevisiae, Trypanosoma cruzi, Pneumocystis carinii and Arabidopsis thaliana expressed in yeast: a model for the development of novel antiparasitic agents.

Autor: Balliano G; Dipartimento di Scienza e Tecnologia del Farmaco, Università di Torino, via P. Giuria 9, 10125 Torino, Italy. gianni.balliano@unito.it, Dehmlow H, Oliaro-Bosso S, Scaldaferri M, Taramino S, Viola F, Caron G, Aebi J, Ackermann J

Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Feb 01; Vol. 19 (3), pp. 718-23. Date of Electronic Publication: 2008 Dec 14.