Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Taraknath Mandal"'
Autor:
Puspangana Singh, Purba Pahari, Srija Mukherjee, Sharmistha Karmakar, Markus Hoffmann, Taraknath Mandal, Dibyendu Kumar Das
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is the fusion machine for host cell entry. Still, the mechanism by which spike protein interacts with the target lipid membrane to facilitate membrane fusion during entry is
Externí odkaz:
https://doaj.org/article/3f8d6371e091477c8713e7f953d20985
Autor:
Kevin C. Courtney, Taraknath Mandal, Nikunj Mehta, Lanxi Wu, Yueqi Li, Debasis Das, Qiang Cui, Edwin R. Chapman
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Synaptotagmin-1 and synaptotagmin-7 are two prominent calcium sensors that regulate exocytosis in neuronal and neuroendocrine cells. Upon binding calcium, both proteins partially penetrate lipid bilayers that bear anionic phospholipids, but
Externí odkaz:
https://doaj.org/article/19831dd6a1864aca958736b4e5832fce
Autor:
Jie Hui, Pu‐Ting Dong, Lijia Liang, Taraknath Mandal, Junjie Li, Erlinda R. Ulloa, Yuewei Zhan, Sebastian Jusuf, Cheng Zong, Mohamed N. Seleem, George Y. Liu, Qiang Cui, Ji‐Xin Cheng
Publikováno v:
Advanced Science, Vol 7, Iss 6, Pp n/a-n/a (2020)
Abstract Confronted with the rapid evolution and dissemination of antibiotic resistance, there is an urgent need to develop alternative treatment strategies for drug‐resistant pathogens. Here, an unconventional approach is presented to restore the
Externí odkaz:
https://doaj.org/article/dbcd162e93024c129ffe703948da2d75
Autor:
Shivam Gupta, Taraknath Mandal
Publikováno v:
Physical Chemistry Chemical Physics. 24:18133-18143
Recent experimental studies revealed that functional membrane microdomains (FMMs) are formed in prokaryotic cells which are structurally and functionally similar to the lipid rafts formed in eukaryotic cells. In this study, we employ coarse-grained m
Publikováno v:
Biophys J
Using the endosomal sorting complex required for transport (ESCRT)-III membrane remodeling complex as an example, we analyze three popular coarse-grained models (the regular MARTINI, polarizable MARTINI (POL-MARTINI), and big multipole water MARTINI
Autor:
Kevin C. Courtney, Taraknath Mandal, Yueqi Li, Nikunj Mehta, Debasis Das, Qiang Cui, Edwin R. Chapman
Ca2+-triggered exocytosis is a crucial aspect of neuronal and neuroendocrine cell function, yet many of the underlying molecular mechanisms that regulate these processes are unknown. Here, we contrast the biophysical properties of two prominent neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bfd87ccf6f91564cb88a3c7f5485ce
https://doi.org/10.1101/2022.07.07.499215
https://doi.org/10.1101/2022.07.07.499215
Autor:
Taraknath Mandal
Publikováno v:
Soft matter. 18(8)
We employ coarse-grained (CG) molecular dynamics simulations (MD) to investigate the effects of the molecular structure of additives on the scission energy and morphology of charged micelles. Considering sodium dodecyl sulfate (SDS) as a representati
Autor:
Kevin C. Courtney, Lanxi Wu, Taraknath Mandal, Mark Swift, Zhao Zhang, Mohammad Alaghemandi, Zhenyong Wu, Mazdak M. Bradberry, Claire Deo, Luke D. Lavis, Niels Volkmann, Dorit Hanein, Qiang Cui, Huan Bao, Edwin R. Chapman
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, 2022, 29 (2), pp.97-107. ⟨10.1038/s41594-021-00716-0⟩
Nat Struct Mol Biol
Nature Structural and Molecular Biology, 2022, 29 (2), pp.97-107. ⟨10.1038/s41594-021-00716-0⟩
Nat Struct Mol Biol
International audience; Neurotransmitter release is mediated by proteins that drive synaptic vesicle fusion with the presynaptic plasma membrane. While soluble N-ethylmaleimide sensitive factor attachment protein receptors (SNAREs) form the core of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fec339b9d0b0a4c70e875f89447ebfb
https://hal.science/hal-04133469
https://hal.science/hal-04133469
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 563:84-94
The influence of a poly(vinyl alcohol) (PVA) molecule on the air/water interfacial structure of adsorbed sodium lauryl ether sulfate with one polyethylene oxide group (SLE1S) was investigated using molecular dynamics simulations. Increasing SLE1S sur
Publikováno v:
J Mol Biol
HIV-1 entry into cells is mediated by the fusion protein gp41. Cholesterol plays an important role in this virus-cell fusion, but molecular structural information about cholesterol-gp41 interaction is so far absent. Here, we present experimental and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e17ad68f777dc0a929e0779c03d636
https://europepmc.org/articles/PMC7781112/
https://europepmc.org/articles/PMC7781112/