Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Taracad K, Venkatachalam"'
Autor:
Kim Frisch, Rajiv Bhalla, Gregory K. Pierens, Damion H.R. Stimson, Taracad K. Venkatachalam, David C. Reutens
Publikováno v:
Venkatachalam, T K, Stimson, D H R, Frisch, K, Pierens, G K, Bhalla, R & Reutens, D C 2019, ' Radiolabeling of protected tryptophan with [ 18 F]fluoromethyl tosylate : Formation of [ 18 F]fluoromethyl ester of tryptophan instead of 1-N-[ 18 F]fluoromethyl tryptophan methylester. ', Applied Radiation and Isotopes, vol. 152, no. October, pp. 172-179 . https://doi.org/10.1016/j.apradiso.2019.06.039
The reaction of [18F]fluoromethyl tosylate with methyl(tert-butoxycarbonyl)-L-tryptophanate results in formation the O-alkylated ester of the tryptophan instead of alkylation of the indole nitrogen of tryptophan as initially anticipated. Treatment of
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:588-595
Our recent investigations for the radiosynthesis of [18 F]fluoromethyl tosylate have highlighted that choice of quaternary methyl ammonium (QMA) cartridge used during the radiosynthesis can significantly impact the radiochemical yields. Often the det
Autor:
Paul V. Bernhardt, Taracad K. Venkatachalam, Damion H.R. Stimson, David C. Reutens, Karine Mardon, Rajiv Bhalla
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 62:321-331
18 F-radiolabeled diphenyl gallium thiosemicarbazone was prepared by [18 F] fluoride exchange of a nitrato anion under mild conditions. The diphenyl gallium thiosemicarbazone chloride is easily prepared in gram quantities and can be used at room temp
Publikováno v:
Journal of Chemical Crystallography. 49:131-138
Gallium complexes of bis-thiosemicarbazones were prepared and characterized using NMR and X-ray crystallography. Formation of a gallium nitrate complex was proven by NMR spectroscopy. Surprisingly, this complex was found to convert on standing to a n
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The repurposing of FDA-approved Bruton’s tyrosine kinase (BTK) inhibitors as therapeutic agents for solid tumors may offer renewed hope for chemotherapy-resistant cancer patients. Here we review the emerging evidence regarding the clinical potentia
Autor:
Rajiv Bhalla, Taracad K. Venkatachalam, Damion H.R. Stimson, David C. Reutens, Gregory K. Pierens
Publikováno v:
Applied Radiation and Isotopes. 131:41-48
[18F]Fluoroethyl tosylate was synthesized using an automated “Synthra” module using ethylene di-tosylate and [18F]fluoride/K222/K2CO3 in acetonitrile. [18F]Fluoroethyl tosylate was purified by semi-preparative HPLC followed by reformulation using
Publikováno v:
Journal of Chemical Crystallography. 47:30-39
NMR and single crystal X-ray structure data for four structurally similar semicarbazones and thiosemicarbazones were compared. In solution, proton NMR showed considerable variation in their chemical shift values especially for the NH2 protons. In the
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 62(9)
Our recent investigations for the radiosynthesis of [
Autor:
Taracad K, Venkatachalam, Damion H R, Stimson, Rajiv, Bhalla, Karine, Mardon, Paul V, Bernhardt, David C, Reutens
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 62(7)
Publikováno v:
Magnetic Resonance in Chemistry. 54:941-946
Two- and three-bond coupling constants (2 JHC and 3 JHC ) were determined for a series of 12 substituted cinnamic acids using a selective 2D inphase/antiphase (IPAP)-single quantum multiple bond correlation (HSQMBC) and 1D proton coupled 13 C NMR exp