Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tara X Metcalfe"'
Autor:
Shruthi Sriramkumar, Tara X Metcalfe, Tim Lai, Xingyue Zong, Fang Fang, Heather M O'Hagan, Kenneth P Nephew
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0271584 (2022)
Ovarian cancer (OC) is a lethal gynecological malignancy with a five-year survival rate of only 46%. Development of resistance to platinum-based chemotherapy is a common cause of high mortality rates among OC patients. Tumor and transcriptomic hetero
Externí odkaz:
https://doaj.org/article/24b51e4e96a748f1b856bef82aac4f3c
Autor:
Shruthi Sriramkumar, Riddhi Sood, Thomas D. Huntington, Ahmed H. Ghobashi, Truc T. Vuong, Tara X. Metcalfe, Weini Wang, Kenneth P. Nephew, Heather M. O’Hagan
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Platinum based agents—cisplatin and carboplatin in combination with taxanes are used for the treatment of ovarian cancer (OC) patients. However, the majority of OC patients develop recurrent, platinum resistant disease that is u
Externí odkaz:
https://doaj.org/article/85d7608e424a4ee082a8b2bdd7825bec
Autor:
Vaishnavi Muralikrishnan, Fang Fang, Tyler C. Given, Ram Podicheti, Mikhail Chtcherbinine, Tara X. Metcalfe, Shruthi Sriramkumar, Heather M. O’Hagan, Thomas D. Hurley, Kenneth P. Nephew
Publikováno v:
Cancers; Volume 14; Issue 14; Pages: 3437
Ovarian cancer is a deadly disease attributed to late-stage detection as well as recurrence and the development of chemoresistance. Ovarian cancer stem cells (OCSCs) are hypothesized to be largely responsible for the emergence of chemoresistant tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4447dea889eb3723012c0b5f9cfa5df7
Publikováno v:
Cancer Research. 83:5804-5804
Ovarian cancer (OC) is one of the deadliest gynecologic cancers in US. Platinum (Pt)-based chemotherapy can reprogram cancer cells to ovarian cancer stem cells (OCSCs) and contribute to incurable recurrence. We have previously shown that Pt-containin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f2dcb60125a06ce865221ab91892cd
https://doi.org/10.1158/1538-7445.am2023-5804
https://doi.org/10.1158/1538-7445.am2023-5804