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pro vyhledávání: '"Tara Sarmiento"'
Autor:
Wenchao Gu, Sijin Luozhong, Simian Cai, Ketaki Londhe, Nadine Elkasri, Robert Hawkins, Zhefan Yuan, Kai Su-Greene, Margaret Cruz, Yu-Wei Chang, Patrick McMullen, Chunyan Wu, Changwoo Seo, Akash Guru, Wenting Gao, Tara Sarmiento, Chris Schaffer, Nozomi Nishimura, Richard Cerione, Melissa Warden, Robert Langer, Shaoyi Jiang
Systemic delivery of mRNAs into disease neurons is first limited by the blood-brain-barrier (BBB). Leukocyte-derived extracellular vesicles (EVs) can cross the BBB at inflammatory sites, emerging as promising carriers to target the disease brain. How
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d704adad513c8f674f9615a7cb69a9b8
https://doi.org/10.1101/2022.12.07.518870
https://doi.org/10.1101/2022.12.07.518870
Autor:
Sijin Luozhong, Zhefan Yuan, Tara Sarmiento, Yu Chen, Wenchao Gu, Caleb McCurdy, Wenting Gao, Ruoxin Li, Stephan Wilkens, Shaoyi Jiang
Publikováno v:
Nano letters. 22(20)
Secondary lymphoid organs (SLOs) are an important target for mRNA delivery in various applications. While the current delivery method relies on the drainage of nanoparticles to lymph nodes by intramuscular (IM) or subcutaneous (SC) injections, an eff