Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Tara R St Amand"'
Autor:
David E. Gutstein, Tara R St Amand, Fangyu Liu, Jonathan A. Epstein, Amanda Schneider, Shasha Liu
Publikováno v:
Development. 133:2063-2073
Connexin 43 (Cx43) is expressed in the embryonic heart, cardiac neural crest (CNC) and neural tube, and germline knockout (KO) of Cx43 results in aberrant cardiac outflow tract (OFT) formation and abnormal coronary deployment. Prior studies suggest a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd4e35b6929fdfae3c7aa8ffd5c1ebc
https://doi.org/10.1242/dev.02374
https://doi.org/10.1242/dev.02374
Autor:
Hanying Chen, Sylvain Pradervand, Sylvia M. Evans, Siew Yen Ho, James R. Feramisco, Mohammad Pashmforoush, Jonathan T. Lu, Wayne R. Giles, Weinian Shou, Michael Silberbach, Tara R St Amand, Bob Clark, Kenneth R. Chien, D. Woodrow Benson, Richard P. Kondo
Publikováno v:
Cell. 117(3):373-386
Human mutations in Nkx2-5 lead to progressive cardiomyopathy and conduction defects via unknown mechanisms. To define these pathways, we generated mice with a ventricular-restricted knockout of Nkx2-5, which display no structural defects but have pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8330b918a12f825b24e8b3c6faed89e2
Autor:
YiPing Chen, Weihong Jiang, Tara R. St. Amand, Igor Kostetskii, Maija H. Zile, Saying Yuan, Ekaterina Kostetskaia
Publikováno v:
Developmental Biology. 223(2):323-338
Vitamin A-deficient (VAD) quail embryos have severe abnormalities, including a high incidence of reversed cardiac situs. Using this model we examined in vivo the physiological function of vitamin A in the left/right (L/R) cardiac asymmetry pathway. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa51ccb1d0bb5a92df3755884d49e38
Autor:
YiPing Chen, Xiang Zhao, Yueping Hu, Tara R. St. Amand, Lan K. Nguyen, Elena V. Semina, Jeffrey C. Murray, Yanding Zhang
Publikováno v:
Developmental Biology. 217:323-332
Members of the Pitx/RIEG family of homeodomain-containing transcription factors have been implicated in vertebrate organogenesis. In this study, we examined the expression and regulation of Pitx1 and Pitx2 during mouse tooth development. Pitx1 expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4cd0e97b9c5b02d70612ef7ebbb535
https://doi.org/10.1006/dbio.1999.9547
https://doi.org/10.1006/dbio.1999.9547
Autor:
Tara R. St. Amand, YiPing Chen, Rajee Ramamurthy, Mengsheng Qiu, Yanding Zhang, Xiang Zhao, Meifeng Zhang, Yueping Hu
Publikováno v:
Developmental Dynamics. 215:45-53
We have used the mouse developing tooth germ as a model system to explore the transmission of Sonic hedgehog (Shh) signal in the induction of Patched (Ptc). In the early developing molar tooth germ, Shh is expressed in the dental epithelium, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14bde59d3066c1490e23cc4724254c20
https://doi.org/10.1002/(sici)1097-0177(199905)215:1<45::aid-dvdy5>3.0.co
https://doi.org/10.1002/(sici)1097-0177(199905)215:1<45::aid-dvdy5>3.0.co
Autor:
YiPing Chen, Jin Ra, Syed I. Baber, Tara R. St. Amand, Yanding Zhang, Yueping Hu, Mengsheng Qiu
Publikováno v:
Biochemical and Biophysical Research Communications. 247:100-105
Asymmetry along the left-right axis of the embryo is a vital feature of vertebrate embryogenesis. In this study, we report the isolation and characterization of a bicoid -related homeobox gene, cPitx2, which displays left-right asymmetric expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fc7dc72108f693305008dae937e2ff
https://doi.org/10.1006/bbrc.1998.8740
https://doi.org/10.1006/bbrc.1998.8740
Publikováno v:
Development of the Cardiac Conduction System: Novartis Foundation Symposium 250
To unravel the complex disease phenotype of heart failure, we are utilizing an integrative approach employing genomics, physiology, and mouse genetics to identify nodal pathways for specific physiological end points such as myocyte stretch activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6d559cc83172bc77d8c133064b643d
https://doi.org/10.1002/0470868066.ch16
https://doi.org/10.1002/0470868066.ch16
Autor:
Jonathan T. Lu, Yusu Gu, Masahiko Hoshijima, Tara R St Amand, John J. Ross, Pilar Ruiz-Lozano, Monica Zamora, Janelle Stricker, Jonathan A. Epstein, Kenneth R. Chien
Publikováno v:
Developmental biology. 291(2)
The heterogeneous cell types of the cardiac conduction system are responsible for coordinating and maintaining rhythmic contractions of the heart. While it has been shown that the cells of the conduction system are derived from myocytes, additional c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e81a3e59d0d0f3d37e3420fd8b169e
https://pubmed.ncbi.nlm.nih.gov/16430881
https://pubmed.ncbi.nlm.nih.gov/16430881
Autor:
Haihong Guo, Hulian Yin, Guangyu Li, Mengsheng Qiu, Tara R. St. Amand, Jun Cai, YiPing Chen, Yanding Zhang
Publikováno v:
Scopus-Elsevier
Rapid accumulating evidence has suggested that the homeodomain transcription factors of the Nkx family play important roles in controlling vertebrate organ patterning and differentiation. In this study, we report the cloning, expression and regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83505ba6f8724af17ef56f2b76a1f5c3
https://pubmed.ncbi.nlm.nih.gov/15672537
https://pubmed.ncbi.nlm.nih.gov/15672537
Autor:
Tomoyuki Nakamura, Mitsuo Iwatate, Toshitaka Yajima, Olivier Muller, Harald Kjekshus, Thierry Pedrazzini, Kenneth R. Chien, Hervé Duplain, Tara R St Amand, Kiyoyuki Matsumura, Sarah Woodard, Sylvain Pradervand, Bernard C. Rossier, Dmitri Firsov, Hideo Yasukawa, John Ross, Masahiko Hoshijima
Publikováno v:
The EMBO journal. 23(22)
The interleukin-6 cytokines, acting via gp130 receptor pathways, play a pivotal role in the reduction of cardiac injury induced by mechanical stress or ischemia and in promoting subsequent adaptive remodeling of the heart. We have now identified the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bff31b270496f53017bd024ea03d230d
https://pubmed.ncbi.nlm.nih.gov/15510217
https://pubmed.ncbi.nlm.nih.gov/15510217