Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Tara McKeown"'
Autor:
Craig Erker, Magimairajan Issai Vanan, Valérie Larouche, Liana Nobre, Chantel Cacciotti, Stéphanie Vairy, Shayna Zelcer, Adam Fleming, Eric Bouffet, Nada Jabado, Geneviève Legault, Samuele Renzi, Tara McKeown, Bruce Crooks, Nirav Thacker, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Sylvia Cheng, Juliette Hukin, Seth Andrew Climans, Mary Jane Lim-Fat, Sarah McKillop, Sarah Lapointe, Mélanie Alves, Julie Bennett, Uri Tabori, Sébastien Perreault
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 4022-4029 (2024)
Background: The treatment of BRAF V600E gliomas with BRAF inhibitors (BRAFis) and MEK inhibitors (MEKis) has been increasingly integrated into clinical practice for pediatric low-grade gliomas (PLGGs) and pediatric high-grade gliomas (HGGs). However,
Externí odkaz:
https://doaj.org/article/18a6d0e5930647838048e65c909b0585
Autor:
Liana Nobre, Michal Zapotocky, Sara Khan, Kohei Fukuoka, Adriana Fonseca, Tara McKeown, David Sumerauer, Ales Vicha, Wieslawa A. Grajkowska, Joanna Trubicka, Kay Ka Wai Li, Ho-Keung Ng, Luca Massimi, Ji Yeoun Lee, Seung-Ki Kim, Shayna Zelcer, Alexandre Vasiljevic, Cécile Faure-Conter, Peter Hauser, Boleslaw Lach, Marie-Lise van Veelen-Vincent, Pim J. French, Erwin G. Van Meir, William A. Weiss, Nalin Gupta, Ian F. Pollack, Ronald L. Hamilton, Amulya A. Nageswara Rao, Caterina Giannini, Joshua B. Rubin, Andrew S. Moore, Lola B. Chambless, Rajeev Vibhakar, Young Shin Ra, Maura Massimino, Roger E. McLendon, Helen Wheeler, Massimo Zollo, Veronica Ferruci, Toshihiro Kumabe, Claudia C. Faria, Jaroslav Sterba, Shin Jung, Enrique López-Aguilar, Jaume Mora, Carlos G. Carlotti, James M. Olson, Sarah Leary, Jason Cain, Lenka Krskova, Josef Zamecnik, Cynthia E. Hawkins, Uri Tabori, Annie Huang, Ute Bartels, Paul A. Northcott, Michael D. Taylor, Stephen Yip, Jordan R. Hansford, Eric Bouffet, Vijay Ramaswamy
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 3, Pp 100038- (2020)
Summary: Over the past decade, wingless-activated (WNT) medulloblastoma has been identified as a candidate for therapy de-escalation based on excellent survival; however, a paucity of relapses has precluded additional analyses of markers of relapse.
Externí odkaz:
https://doaj.org/article/fe064d5dfe04450eab73d80ac7fe7dce
Autor:
Jen Chun Foo, Inci Yaman Bajin, Oksana Marushchak, Tara McKeown, Eric Bouffet, Derek S. Tsang, Norman Laperriere, Peter Dirks, James Drake, Birgit Ertl-Wagner, Ute Bartels
Publikováno v:
Journal of Neuro-Oncology. 162:443-448
Purpose: To determine long-term outcomes of a cohort of children with germinoma treated with chemotherapy and radiation therapy without primary tumor boost even in the absence of complete response to chemotherapy. Methods: This retrospective study an
Publikováno v:
Artificial Intelligence and Online Engineering ISBN: 9783031170904
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::948d78a2dc18dfbf5c20e437c20fd845
https://doi.org/10.1007/978-3-031-17091-1_36
https://doi.org/10.1007/978-3-031-17091-1_36
Autor:
Dorsa Sadat Kiaei, Valerie Larouche, Jean-Claude Décarie, Uri Tabori, Cynthia Hawkins, Sarah Lippe, Benjamin Ellezam, Luis H Ospina, Yves Theoret, Leandra Desjardins, Marie-Elaine Metras, Serge Sultan, Edith Cantin, Marie-Eve Routhier, Chantal Mailloux, Marie-claude Bertrand, Maxime Caru, Tara McKeown, Stephanie Vairy, Geneviève Legault, Eric Bouffet, Vijay Ramaswamy, Hallie Coltin, Lucie Lafay-Cousin, Juliette Hukin, Craig Erker, Nada Jabado, Mathieu Dehaes, Sébastien Perreault
Publikováno v:
Neuro-Oncology. 24:vii70-vii70
BACKGROUND Plexiform neurofibromas (PN) are observed in up to 50% of patients with neurofibromatosis type 1 (NF1). Trametinib has been used widely to treat PN but limited data has been reported on its efficacy within a clinical trial. METHODS This on
Publikováno v:
DeSE
The use of technology and Artificial Intelligence is becoming much more apparent in our lives, especially, in the many working environments that there are; FinTech, Medicine, Education, and more recently, Legal Tech. The paper provides the background
Publikováno v:
Pediatric bloodcancerREFERENCES. 67(12)
Clinical trials of MEK inhibitors are underway in pediatric low-grade glioma (PLGG) with BRAF oncogene mutations and recurrent/refractory disease. Cognitive and behavioral impacts of MEK inhibitors, such as trametinib, are unknown as these outcomes h
Autor:
Cynthia Hawkins, Josef Zamecnik, David D. Eisenstat, Andres Morales La Madrid, Didier Frappaz, Adela Cañete, Valerie Larouche, Liana Nobre, Sarah Leary, Murali Chintagumpala, Lili-Naz Hazrati, Valentina Iurilli, Normand Laperriere, Peter Hauser, Scott L. Coven, Lenka Krskova, Jonathan L. Finlay, Jordan R. Hansford, Vijay Ramaswamy, Giovanni Morana, Julia Balaguer Guill, Palma Solano, Samantha Mascelli, Gurcharanjeet Kaur, Helen Toledano, Peter B. Dirks, Olaf Witt, Ute Bartels, Bev Wilson, Uri Tabori, Cornelis M. van Tilburg, Sarah Injac, Eduardo Quiroga-Cantero, Cecile Faure Conter, Ira J. Dunkel, Jaroslav Sterba, Duarte Salgado, Magnus Sabel, Diana S Osorio, Till Milde, Matthias A. Karajannis, Inga Harting, Zdenek Pavelka, Tara McKeown, Naureen Mushtaq, Daniel Alderete, Michal Zapotocky, Julie Bennett, Ofelia Cruz, Scott Ryall, Abhishek Bavle, James T. Rutka, Frank Lin, Elizabeth Finch, Frank van Landeghem, Anne Grete Bechensteen, Maria Luisa Garrè, Michael D. Taylor, Alvaro Lassaletta, Derek S. Tsang, Karen Gauvain, Daniel R. Boue, Jack Su, David Sumerauer, Sonika Dahiya, Helena Mörse, Annie Huang, Roger J. Packer, Lorena V Baroni, Martin Kyncl, Miriam Bornhorst, Eric Bouffet, Mariana Fernandes
Publikováno v:
JCO Precis Oncol
Jco Precision Oncology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Jco Precision Oncology
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
PURPOSE Children with pediatric gliomas harboring a BRAF V600E mutation have poor outcomes with current chemoradiotherapy strategies. Our aim was to study the role of targeted BRAF inhibition in these tumors. PATIENTS AND METHODS We collected clinica
Autor:
Tara McKeown, Eric Bouffet, Seung-Ki Kim, Amulya A. Nageswara Rao, Liana Nobre, Andrew S. Moore, Joshua B. Rubin, Toshihiro Kumabe, Maura Massimino, James M. Olson, Sara Khan, Rajeev Vibhakar, Ales Vicha, Ho Keung Ng, Lenka Krskova, Wiesława Grajkowska, Jason E. Cain, Joanna Trubicka, Enrique López-Aguilar, Shayna Zelcer, Marie Lise van Veelen-Vincent, Ji Yeoun Lee, Alexandre Vasiljevic, Young Shin Ra, Ian F. Pollack, Massimo Zollo, Kohei Fukuoka, Boleslaw Lach, Carlos Gilberto Carlotti, Claudia C. Faria, Jordan R. Hansford, Shin Jung, David Sumerauer, Paul A. Northcott, Roger E. McLendon, Kay Ka Wai Li, Michal Zapotocky, Annie Huang, Peter Hauser, William A. Weiss, Lola B. Chambless, Josef Zamecnik, Ronald L. Hamilton, Cécile Faure-Conter, Sarah Leary, Vijay Ramaswamy, Helen Wheeler, Jaume Mora, Pim J. French, Erwin G. Van Meir, Ute Bartels, Adriana Fonseca, Luca Massimi, Stephen Yip, Jaroslav Sterba, Caterina Giannini, Michael D. Taylor, Nalin Gupta, Uri Tabori, Cynthia Hawkins, Veronica Ferruci
Publikováno v:
Cell reports. Medicine, vol 1, iss 3
Cell Reports Medicine, Vol 1, Iss 3, Pp 100038-(2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Reports Medicine, 1(3):100038. Cell Press
Cell reports. Medicine
Cell Reports Medicine, Vol 1, Iss 3, Pp 100038-(2020)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cell Reports Medicine, 1(3):100038. Cell Press
Cell reports. Medicine
SUMMARY Over the past decade, wingless-activated (WNT) medulloblastoma has been identified as a candidate for therapy de-escalation based on excellent survival; however, a paucity of relapses has precluded additional analyses of markers of relapse. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65edca0ea6affe6d717079bfc90a0b95
http://hdl.handle.net/11588/829322
http://hdl.handle.net/11588/829322
Publikováno v:
Neuro-Oncology
BACKGROUND The recent advancement in treating pediatric low grade glioma has led to upfront use of MEK and BRAF (MAPK) inhibitor therapy. At the Hospital for Sick Children we are the National leaders in treating pediatric oncology diagnosis with MAPK