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Autor:
Lauren M. Adams, Caroline J. DeHart, Bryon S. Drown, Lissa C. Anderson, William Bocik, Emily S. Boja, Tara M. Hiltke, Christopher L. Hendrickson, Henry Rodriguez, Michael Caldwell, Reza Vafabakhsh, Neil L. Kelleher
Publikováno v:
The Journal of biological chemistry. 299(1)
The KRAS gene is one of the most frequently mutated oncogenes in human cancer and gives rise to two isoforms, KRAS4A and KRAS4B. KRAS post-translational modifications (PTMs) have the potential to influence downstream signaling. However, the relations