Výsledky vyhledávání - "Tara M. Engeman"

Intraallograft Chemokine RNA and Protein During Rejection of MHC-Matched/Multiple Minor Histocompatibility-Disparate Skin Grafts

Autor: Thomas A. Hamilton, Tara M. Engeman, Shoji Koga, David R. Paolone, Charles S. Tannenbaum, Robert L. Fairchild, Yoshihiko Watarai

Publikováno v: The Journal of Immunology. 164:6027-6033

Chemokines direct leukocyte recruitment into sites of tissue inflammation and may facilitate recruitment of leukocytes into allografts following transplantation. Although the expression of chemokines during rejection of MHC-disparate allografts has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354a06c3d135bd036adf057f750cf168
https://doi.org/10.4049/jimmunol.164.11.6027

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Inhibition of Functional T Cell Priming and Contact Hypersensitivity Responses by Treatment with Anti-Secondary Lymphoid Chemokine Antibody During Hapten Sensitization

Autor: Robert L. Fairchild, Anton V. Gorbachev, Ronald P. Gladue, Tara M. Engeman, Peter S. Heeger

Publikováno v: The Journal of Immunology. 164:5207-5214

Recent studies have suggested a pivotal role for secondary lymphoid chemokine (SLC) in directing dendritic cell trafficking from peripheral to lymphoid tissues. As an extension of these studies, we examined the consequences of anti-SLC Ab treatment d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ad118a01c3907dbbf51bacd968824b
https://doi.org/10.4049/jimmunol.164.10.5207

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EARLY EXPRESSION OF INTERFERON-?? INDUCIBLE PROTEIN 10 AND MONOKINE INDUCED BY INTERFERON-?? IN CARDIAC ALLOGRAFTS IS MEDIATED BY CD8+ T CELLS1

Autor: Anil Kapoor, Robert L. Fairchild, Tara M. Engeman, Michael G. Hobart, Shoji Koga, Ken Morita, Evan M. Vapnek

Publikováno v: Transplantation. 69:1147-1155

BACKGROUND Our goal was to test the intragraft mRNA expression and production of two chemokines that are potent chemoattractants for antigen-primed T cells, interferon-gamma inducible protein 10 (IP-10) and monokine-induced by IFN-gamma, (Mig), in al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1c9b345ffdfdb84f1c39be472e53995
https://doi.org/10.1097/00007890-200003270-00020

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T Cell Infiltration into Class II MHC-Disparate Allografts and Acute Rejection Is Dependent on the IFN-γ-Induced Chemokine Mig

Autor: Shoji Koga, Michael B. Auerbach, Tara M. Engeman, Andrew C. Novick, Hiroshi Toma, Robert L. Fairchild

Publikováno v: The Journal of Immunology. 163:4878-4885

Direct evidence that cytokines with chemoattractant properties for leukocytes, chemokines, recruit alloantigen-primed T cells into transplanted allografts has been lacking. We present evidence that neutralization of a single chemokine inhibits T cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::725b0726ffc1230683bd3886b1811923
https://doi.org/10.4049/jimmunol.163.9.4878

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Groα-mediated recruitment of neutrophils is required for elicitation of contact hypersensitivity

Autor: Thomas A. Hamilton, Charles S. Tannenbaum, Robert L. Fairchild, David A. Armstrong, Tara M. Engeman, Nancy A. Dilulio

Publikováno v: European Journal of Immunology. 29:3485-3495

The factors mediating recruitment of immune T cells to challenge sites during contact hypersensitivity (CHS) responses remain unclear. To investigate the role of chemokines during elicitation of CHS, the temporal expression of chemokine genes in hapt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::52447839c7aebc3243247d9dd9393a08
https://doi.org/10.1002/(sici)1521-4141(199911)29:11<3485::aid-immu3485>3.0.co

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Early chemokine cascades in murine cardiac grafts regulate T cell recruitment and progression of acute allograft rejection

Autor: Daniel G. Remick, Tara M. Engeman, Masayoshi Miura, David R. Paolone, Anil Kapoor, Ken Morita, Robert L. Fairchild

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 167(5)

The identification of early inflammatory events after transplant in solid tissue organ grafts that may direct T cell recruitment and promote acute allograft rejection remain largely unknown. To better understand temporal aspects of early inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d5513e78bbfee265bf91dfe94d26f8
https://pubmed.ncbi.nlm.nih.gov/11509648

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Negative Regulation of CD8+ T Cell Function by the IFN-Induced and Double-Stranded RNA-Activated Kinase PKR

Autor: Robert L. Fairchild, Tara M. Engeman, Bryan R.G. Williams, Yi-Li Yang, Hui Xu, Suzanne Kadereit

The IFN-induced and dsRNA-activated kinase (PKR) mediates the antiviral and antiproliferative effects of IFN-α and IFN-γ. Despite these findings, Pkr−/− mice have no overt immunological phenotype. Here we tested the role of PKR in cellular immu

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